摘要:

AbstractA male patient with advanced breast cancer had no response to orchiectomy but subsequently enjoyed a 17‐month partial response to tamoxifen 10 mg B.I.D. His tumor estrogen receptor (ER) protein was 555 fmol protein/ml cytosol. The potential role of ER determinations in the selection of therapy for advanced male breast cancer is discusse

ISSN:0022-4790    

DOI:10.1002/jso.2930250112

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

摘要:

AbstractA 75‐year‐old man developed neurilemmoma of the left eighth cranial nerve, adenomatous polyp of the sigmoid colon, adenocarcinoma of the prostate, mixed cell type lymphoma of the right neck, and infiltrating ductal carcinoma of the right breast metachronously during a period of 38 years. The cancer of the right breast occurred 7 years after the long‐term stilbesterol treatment of prostatic carcinoma, which suggests a causal relationship between the hormonal therapy and development of breast carc

ISSN:0022-4790    

DOI:10.1002/jso.2930250113

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

摘要:

AbstractWe report on a 56‐year‐old man who had two distinct and separate primary tumors of the bladder simultaneously: one mucin‐producing adenocarcinoma and the other a transitional cell carcinoma. Despite local extension of the adenocarcinoma beyond the bladder wall, surgical resection has resulted in a 6‐year recurrence‐free survival of th

ISSN:0022-4790    

DOI:10.1002/jso.2930250114

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

摘要:

AbstractPatients with large advanced tumors of the head and neck that are resectable may be reconstructed by using the combination of an ipsilateral pectoralis major myocutaneous flap and an ipsilateral deltopectoral flap. Preoperative planning is necessary. The PM flap must be elevated and care taken not to interfere with the internal mammary perforating arteries. The lateral chest incision must be made low enough to provide adequate skin and soft tissue in the DP flap. These two flaps provide adequate tissue with a reliable blood supply to reconstruct these large defects.

ISSN:0022-4790    

DOI:10.1002/jso.2930250115

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

摘要:

AbstractHuman large bowel neoplasia seems to be caused by environmental carcinogens. The experimental carcinogen, 1,2‐dimethylhydrazine (DMH), must be oxidized in the body to have effect. The antioxidants, butylated hydroxyanisole (BHA) and ascorbic acid, were tested for efficacy in prevention of experimental large bowel neoplasia.Carcinogenesis was induced in female CF‐1 mice by administering DMH, 20 mg/kg, sq for 24 weekly doses. Test animals received varying doses of ascorbic acid, BHA, or both agents together. Animals were sacrificed when moribund or at 35 weeks. All colons were totally embedded and analyzed histologically.Ascorbic acid demonstrated no effects on incidence or density of large bowel tumors. Ascorbic acid did increase the ratio of adenomas to adenocarcinomas. BHA decreased the incidence and density of large bowel tumors. The lowest incidence was obtained in the group receiving both agents combined.It is concluded that BHA is effective in the chemoprevention of DMH‐induced large bowel neoplasms. Ascorbic acid demonstrates only modest effect. The greatest effect on tumor incidence is seen when ascorbic acid and BHA are administered tog

ISSN:0022-4790    

DOI:10.1002/jso.2930250116

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

摘要:

AbstractA rare case of squamous carcinoma of the thymus is described and the literature is reviewed. This type of thymic carcinoma is surgically curable even in the presence of local invasion. It also appears radiosensitive with apparent cure by radiotherapy alone observed. Its prognosis is better than squamous carcinoma of the lung with mediastinal involvement, and lymphoepithelioma‐like thymic carcinom

ISSN:0022-4790    

DOI:10.1002/jso.2930250117

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

摘要:

AbstractAn intraspinal epidermoid cyst occurring in the lumbo‐sacral region of a 38–year old man with congenital spina bifida occulta is described. Relevant literature on the subject is revie

ISSN:0022-4790    

DOI:10.1002/jso.2930250118

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

摘要:

AbstractA case of a large localized fibrous mesothelioma of pleura is described and the literature is reviewed. The histogenesis of this rare tumor is discussed.

ISSN:0022-4790    

DOI:10.1002/jso.2930250119

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

摘要:

AbstractThe survival of nonprivate and private patients following orchiectomy for stage D adenocarcinoma of the prostate was studied. While the private patients enjoyed a longer survival, their improved survival was found to be a function of an earlier presentation. Examination of the survival statistics with linear regression analysis suggested that survival following orchiectomy is a function of the age at the time of orchiectomy.

ISSN:0022-4790    

DOI:10.1002/jso.2930250120

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

ISSN:0022-4790    

DOI:10.1002/jso.2930250101

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY