摘要:

AbstractTextbook accounts of this subject are inadequate. This review considers the work of Cooper and Salmon and reproduces some of their figures. Applications in the diagnosis and treatment of cancer are discussed. The largest mammary arteries are the lateral (from the axillary) and the anterior medial and posterior medial (from the internal thoracic). The branches of these arteries do not follow the duct system, but instead form a plexus in the anterior fat layer. Normally there are no hypervascular or hypovascular areas. The contribution of the mammary branches of the posterior (aortic) intercostal arteries is minor. There are superficial and deep sets of veins, the latter associated with arteries. Mammary vessels of living women are demonstrated by infrared photography, thermography, and mammography. In the diagnostic use of these methods there is a tendency to rely upon the concept of normal vascular symmetry, but this is a fallacy.

ISSN:0022-4790    

DOI:10.1002/jso.2930090112

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1977

数据来源: WILEY

摘要:

AbstractPapillary tumors of the skin of the land invertebrate Lehmannia poirieri (a gastropod) could not be induced by using a potent vertebrate carcinogen. With the same agent 7,12‐dimethylbenz (a) anthracene papillary tumors can readily be induced in mice. The resistance of this invertebrate to a known vertebrate carcinogen is discussed and the ramifications are conjecture

ISSN:0022-4790    

DOI:10.1002/jso.2930090113

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1977

数据来源: WILEY

摘要:

AbstractTwenty‐nine histologically verified cases of Paget's disease of the breast treated at the Hadassah University Hospital in the years 1949–1972 were followed up and analyzed. Dividing this material into two groups according to the presence or absence of a palpable breast tumor revealed significant difference in behavior and survival. Patients with a breast mass (34%) had a 50% axillary lymph node involvement and behaved as with any other ordinary breast cancer, with a 5‐year survival rate of 40% and a 10‐year survival rate of 33%. Patients with no palpable breast mass (66%) had only a 10.5% lymph node involvement, the 5‐year survival rate being 94% and the 10‐year survival rate being 91%. Delay in diagnosis seems to play no significant factor in survival rates and outcome. We believe radical mastectomy to be the treatment of choice in all cases of Paget's disease of

ISSN:0022-4790    

DOI:10.1002/jso.2930090114

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1977

数据来源: WILEY

摘要:

AbstractThree hundred and seventy‐one mice of the C3H/St inbreds bearing spontaneous tumors of mammary gland origin have been used in this experiment. All mice studied were lineal descendents of a tumorbearing mouse which had been injected with a liver extract. In this descent there appears to be a transmissible entity presumably induced by the injection of the liver extract.Following 15 generations of inbreeding after the appearance of a transmissible entity, a second sudden reversal of effect on cancer growth in mice has been indicated.This change has progressively altered the growth of cancer from a very low effect to a maximal effect, i.e., to a complete regression of a high percentage of the tumor.The maximal effect of the transmissible entity is the complete suppression of the growth of cancer during, at least, through the 25th period of observation, thus producing negative values of tumor growth.All these effects of the growth and fate of spontaneous tumors of mammary gland origin in mice have been obtained in a single lineal descent of C3H/St inbreds without resorting to any outcros

ISSN:0022-4790    

DOI:10.1002/jso.2930090115

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1977

数据来源: WILEY

ISSN:0022-4790    

DOI:10.1002/jso.2930090116

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1977

数据来源: WILEY

ISSN:0022-4790    

DOI:10.1002/jso.2930090101

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1977

数据来源: WILEY