摘要:

AbstractMalignant mesothelioma presenting in the pleura and peritoneum is described in a middle‐aged man. The patient lacked significant asbestos exposure which is not unexpected from both the clinical literature and animal inhalation tumor data. Computerized axial tomographic correlation is provided. Partial remission was achieved with the administration of adriamycin and DTI

ISSN:0022-4790    

DOI:10.1002/jso.2930110302

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

摘要:

AbstractInformation on metastases from carcinoma of the mammary gland in an autopsy study of 707 cases occurring in white women over a 15‐year period are presented and tabulated.Multiple primary cancers occurred in 19% of the cases. Of the 137 cases that exhibit more than one neoplastic malignancy, 31 (23%) were present in the contralateral mammary gland. Seventy patients had no metastasis from the mammary cancer at the time of death, and 55 of these patients had another cancer.Additional information has been added concerning the frequency of metastasis in parathyroid and thymus. When a parathyroid contains a metastasis, extensive metastases were noted in many organs and thus represents a late stage of the cance

ISSN:0022-4790    

DOI:10.1002/jso.2930110303

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

摘要:

AbstractThe adaptation of the principles of electrocoagulation to controlling symptomatic cutaneous metastatic disease is discussed. The technique permits minimal anesthesia, excellent hemostasis, local control, satisfactory cosmesis with reduced hospitalization. Two illustrative cases are reported of metastatic malignant melanoma and metastatic leiomyosarcoma.

ISSN:0022-4790    

DOI:10.1002/jso.2930110304

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

摘要:

AbstractEsophageal achalasia has not been reported in the literature as a complication of Hodgkin disease. Involvement of the esophagus is rare but when present, consists mostly of bleeding, ulceration or diverticuli. A case is reported in a fifty‐one year old female with achalasia of the distal third of the esophagus associated with Hodgkin disease, Stage II

ISSN:0022-4790    

DOI:10.1002/jso.2930110305

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

摘要:

AbstractPatients categorized according to tumor type were compared to a control nontumor population. Comparison of relative T cell values among the groups showed no significant differences; however, when absolute numbers of T cells/ mm3were compared, all cancer patients, whether from treated or untreated groups, had significantly depressed T cell values. No significant differences were observed in the relative or absolute numbers of B cells. Comparison of the total lymphocyte response to PHA showed no significant differences among the various cancer groups; however, response in all cancer groups whether from treated or untreated patients, was depressed by comparison to the control group. Patients categorized according to the type of treatment received showed significant depression in the white blood cell count, lymphocyte count, relative and absolute T cell counts and the absolute B cell count in the postsurgery, postadjunctive therapy group. The pretherapy group also showed significant depression in the absolute number of T cells/mm3when compared to the controls. Response to PHA correlated with the absolute T cell values.

ISSN:0022-4790    

DOI:10.1002/jso.2930110306

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

摘要:

AbstractIn a retrospective study, 58 patients with advanced colorectal carcinoma received one or more 5‐day infusions of 5‐FU at 20 mg/kg per 24 hours followed by weekly IV 5‐FU at 15 mg/kg. In 36 patients who received the infusion as first treatment (Group A), the response rate was 23% with a median duration of response of 8.0 months. No improvement in survival was noted. In 22 patients treated with the infusion after relapse on weekly 5‐FU (Group B), the response rate was 10.5% with a median duration of response of 4.5 months. Stable disease for 3‐6 months was seen in 21%. Survival in Group B was improved when compared with a similar group of patients treated by weekly 5‐FU without infusion (Group CB), but statistical significance was not obtained. Twenty percent of patients were alive two years after relapsing on weekly 5‐FU when given the five‐day infusion of 5‐FU and re‐initiated on weekly 5‐FU.Toxicity t o the five‐day infusion of 5‐FU was minimal. Three of 69 (4.3%) infusions were not completed because of toxicity.A separate review of procarbazine indicated that it was minimally active in colorectal carcinoma.Other patients with gastric and pancreatic carcinoma were reviewed but no statistical significance for 5‐FU infusion was seen for survival.A five day continuous infusion of 5‐FU is recommended for colorectal cancer patients who relapse on weekly 5‐FU therapy. Further study of the infusion in combination with

ISSN:0022-4790    

DOI:10.1002/jso.2930110307

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

摘要:

AbstractIn Rochester, New York, 606 women were treated with ionizing radiation for post‐partum mastitis, mostly between 1940 and 1955. Two‐thirds of all breasts were treated, the average dose per breast being 377 rads (at 2.5 cm breast depth). Mammographic examinations were performed on 265 of these women still residing in this vicinity. Two nonpalpable carcinomas (with no axillary node metastases) were found in the twelve breast lesions that have been biopsied. Some of the biopsies revealed premalignant changes. It is recommended that women in this high‐risk category have close medical supervision, as well as periodic mammographic evaluation, and that the importance of periodic breast self‐examinations should be emp

ISSN:0022-4790    

DOI:10.1002/jso.2930110308

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

摘要:

AbstractOf 49 patients with midgut and hindgut carcinoids, second primary distinct carcinomas occurred in 12. The most aggressive carcinoids were the 24 that arose in the distal small bowel and cecum. Of the patients affected, 15 had lymph node metastases and eight had liver metastases at the time of diagnosis. That only five patients were completely relieved of symptoms following resection was partially explained by autopsy findings in 15 patients, six of whom had metastatic extra‐abdominal carcinoid without liver metastases (most commonly, bone metastases

ISSN:0022-4790    

DOI:10.1002/jso.2930110309

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

摘要:

AbstractThe only effective therapy for non‐small‐cell lung cancers has been surgical resection. In the present study a patient with unresectable adenocarcinoma of the lung was treated by chemoimmunotherapy and surgery, and has been doing well for 19 months following surgery. The case is presented as an example of treatment of advanced lung cancer by combined modality appro

ISSN:0022-4790    

DOI:10.1002/jso.2930110310

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY

摘要:

AbstractFibroxanthosarcoma is a variant of malignant fibrous histiocytoma probably derived from the primitive tissue histiocyte. It occurs rarely in the head and neck. This lesion may be confused with the benign atypical fibroxanthoma. However, newer histologic criteria may allow definitive differential diagnosis which is important because of the aggressive biologic behavior of fibroxan‐ thosarcoma. Aggressive initial surgery with a consideration of regional lympha‐ denopathy offers the best chance for c

ISSN:0022-4790    

DOI:10.1002/jso.2930110311

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1979

数据来源: WILEY