摘要:

AbstractSquamous cell carcinoma that developed in branchial cleft cyst in a 53‐year‐old male is described. The tumor was focally invasive. The tumor fulfilled criteria advocated by Martin for substantiating carcinoma as primary in the branchial cleft cyst.The patient has survived for 4.5 years after radical neck dissection and radiation without manifesting primary or recurrent tumor locally or elsewhere.One of the major critera in diagnosing squamous cell carcinoma as primary tumor in the branchiogenic cyst is to prove that it has arisen in normal epithelial lining [2, 3].In our case there is transition of the tumor from normal squamous epithelial lining of the cyst to maligna

ISSN:0022-4790    

DOI:10.1002/jso.2930200402

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1982

数据来源: WILEY

摘要:

AbstractThe present study dearly demonstrates that neurofibromas and neurofibrosarcomas are devoid of cytosol receptor for steroid. These observations are in sharp contrast to the significant incidence of receptors in soft tissue and osseous sarcomas and raise doubts that steroids exert a direct effect on the growth of these tumors.

ISSN:0022-4790    

DOI:10.1002/jso.2930200403

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1982

数据来源: WILEY

摘要:

AbstractFour common‐sense untoward factors (age over 60, pneumonectomy, microresidual disease, and postoperative empyema) were retrospectively evaluated in a consecutive series of 199 surgically apparently complete non‐oat cell lung cancer resections. By single‐factor analysis all factors showed a lower survival that was contingent for microresidual disease and age over 60. For stage I tumors the negative impact on survival was significant for all except empyema, and for stage II and III tumors only for empyema. Without confounding factors, microresidual disease and age over 60 were negative prognostic factors only for distant mortality, empyema a negative prognostic factor only for early mortality, and pneumonectomy a probable negative prognostic factor for both early and distant mortality. It is concluded that the scientific method used confirmed the prognostic assessment of common sense for these four fa

ISSN:0022-4790    

DOI:10.1002/jso.2930200404

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1982

数据来源: WILEY

摘要:

AbstractA new holographic technique is utilized to obtain in vivo three dimensional photographic records. The development of a holographic endoscopic camera (endoholoscope or holocamera) provides a unique method of diagnosis of internal organs and tissues. A hologram of the larynx of an anesthetized dog shows details which could not be observed by indirect laryngoscopy.

ISSN:0022-4790    

DOI:10.1002/jso.2930200405

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1982

数据来源: WILEY

摘要:

AbstractA rabbit brain tumor model is described using transplanted VX‐2 carcinoma. The mean survival time after tumor transplantation was 9.3 days, and the reproducibility rate was 90%. In addition, this new model offers significant advantages over previously reported brain tumor models in terms of ease of induction and shortened latency time

ISSN:0022-4790    

DOI:10.1002/jso.2930200406

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1982

数据来源: WILEY

摘要:

AbstractSera from patients receiving autologous cell immunization were shown to contain antibody specific for melanoma cells by immunofluorescence, microcomplement fixation, and mixed hemadsorption. These hyperimmune specific sera were used to define antigens shed into tissue culture media from human malignant melanoma cells. When supernatants from cultured melanoma cells were passed over a Sephadex G‐200 column, melanoma‐antigens were found in Peak 2. The active fraction was further purified by carboxymethylcellulose ion exchanger and found in the 0.4 M NaCl gradient. This fraction has been tested in four immunized patients and in one nonimmunized melanoma patient. All five patients developed lymphocytic vasculitis compatible with delayed hypersensitivity reaction. These antigens should be of benefit in studying delayed hypersensitivity in melanoma patients and as potential agents for specific immunother

ISSN:0022-4790    

DOI:10.1002/jso.2930200407

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1982

数据来源: WILEY

摘要:

AbstractThree patients who presented with a clinically solitary intraparotid metastasis from breast carcinoma are reported. The entity of metastatic disease in the parotid gland is reviewed. The importance of histologic distinction between primary and metastatic neoplasms of the parotid and the treatment approach are stressed.

ISSN:0022-4790    

DOI:10.1002/jso.2930200408

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1982

数据来源: WILEY

摘要:

AbstractAn improved technique for exposing a lymph vessel prior to cannulation is introduced. This involves one clean incision and minimal dissection. Utilizing this technique, a vessel can be exposed within a minute. Damage to the skin and subcutaneous tissue is minimal. Leaking and procedure failures are rare. Fast healing occurs due to minimal incision length and trauma.

ISSN:0022-4790    

DOI:10.1002/jso.2930200409

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1982

数据来源: WILEY

摘要:

AbstractForty‐three patients with Stage III or IV squamous cell carcinoma of the head and neck were treated with simultaneous hydroxyurea and bleomycin in four treatment levels and with full‐dose radiotherapy. Complete responses ranged from 28 to 50% (P = .47), and complete plus partial responses ranged from 57 to 84% (P = .50), in a total of 33 patients. The primary toxicity was moderate to severe mucositis and minimal leukopenia. Despite good initial response, long‐term survival duration was not greater than was that for historical con

ISSN:0022-4790    

DOI:10.1002/jso.2930200410

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1982

数据来源: WILEY

摘要:

AbstractWe review a series of 100 consecutive cases of malignancy treated for as cites with abdominal paracentesis. The results of treatment for ascites with intracavitary Thiotepa are reported for 23 patients. The temporary partial response rate was 8/23 (35%) patients. There were symptoms of intestinal obstruction in five patients (22%) treated with Thiotepa, and one of these patients died of intestinal obstruction. In 60% of autopsied patients there were abundant intestinal adhesions in the peritoneal cavity after Thiotepa. We concluded that Thiotepa is contraindicated for instillation into the peritoneal cavity. The median survival time for patients with carcinoma of the mammary gland was 47 days, carcinoma of the ovary 121 days, and carcinoma of the large intestine 54 days after the first abdominal paracentesis. We found that patients without clinical liver metastasis at the time of first abdominal paracentesis had almost three times longer median survival time than that of patients with metastatic liver. In four cases the immediate cause of death was a complication of an abdominal paracentesis.

ISSN:0022-4790    

DOI:10.1002/jso.2930200411

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1982

数据来源: WILEY