摘要:

AbstractThe 60 patients of gastrointestinal cancer comprising this study were in the age range of 29–70 years with 39 males and 21 females. The primary sites of cancer were: gallbladder 19, colon 13, stomach 12, anorectum 8, and liver 8. The stage of tumor spread was localized in 32 and metastatic in 28 cases. Round cell infiltration scores were classified semiquantitatively from O‐V. Cellular immunity as expressed by the blood lymphocyte count and DNCB reactivity was also studied. Round cell infiltration was dense in the localized group (P<0.0005). The mean lymphocyte counts in all the primary sites of gastrointestinal cancer were significantly higher in the localized group as compared to metastatic group. The DNCB reactivity showed anergy in six cases and poor response in the remaining 22 cases of metastatic group. There was a statistically significant correlation between lymphoreticular infiltration, peripheral blood lymphocyte count, and the DNCB reactivity. Diminished round cell infiltration, lymphopenia, and depressed DNCB response indicate an advanced stage of gastrointestinal can

ISSN:0022-4790    

DOI:10.1002/jso.2930160302

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1981

数据来源: WILEY

摘要:

AbstractUrinary immunoglobulin A levels were measured in the urine of 13 patients with histologically diagnosed bladder cancer present, six patients with culture proven urinary tract infection, and 14 control individuals. There were statistically significantly higher immunoglobulin A levels in the urine of patients with bladder cancer than in either individuals with urinary tract infection or control individuals. Urinary immunoglobulin A may be a potentially useful test for the diagnosis and follow‐up of bladder cancer patient

ISSN:0022-4790    

DOI:10.1002/jso.2930160303

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1981

数据来源: WILEY

摘要:

AbstractThe filarial parasite Dirofilaria immitis (dog “heartworm”) is the cause of a progressive zoonosis among canine species in the United States; it is rarely transmitted to man, in whom it can present as a solitary lung nodule. There are currently no reliable clinical or radiologic features to distinguish it from other solitary necrotizing granulomas, and thoracotomy is currently the only means of establishing the diagnosis. D. immitis can be identified and properly classified by routine light microscopy despite being immature and partially necrotic. Canine Dirofilariasis may well assume even greater medical importance because of its expanding geographic range and the concomitant increase in the number of cases observed among hum

ISSN:0022-4790    

DOI:10.1002/jso.2930160304

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1981

数据来源: WILEY

摘要:

AbstractThe extent of surgery in the treatment of primary hyperparathyroidism should be based on the pathologic entity of the disease. In neoplasia (either the common adenoma or the rare carcinoma), excision of the diseases parathyroid will generally suffice to cure the disease, but in primary hyperplasia, the removal of all the diseased glands except for a small amount of glandular tissue is required. The pathologic diagnosis of primary hyperparathyroidism can usually be made by a macroscopic assessment of the parathyroid. It is further delineated by the density test and confirmed by Sudan fat‐frozen section examinatio

ISSN:0022-4790    

DOI:10.1002/jso.2930160305

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1981

数据来源: WILEY

摘要:

AbstractThe surgical oncologist is sometimes confronted with a patient who was surgically treated for cancer of the thyroid gland and now has recurrent disease. In most instances, additional surgical treatment is indicated. The magnitude of surgery is primarily determined by the amount of tissue removed at the original operation.Surgery for recurrent disease may include completion of total thyroidectomy with dissection of lymphatic tissues in the thyroid compartment or/and neck dissection, preferably modified. Several clinical situations are outlined and discussed.

ISSN:0022-4790    

DOI:10.1002/jso.2930160306

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1981

数据来源: WILEY

摘要:

AbstractPatient with goiter usually has benign disease. While investigation is important, clinical factors weigh heavily in the diagnosis of cancer. Aside from serum calcitonin and CEA, biochemical findings are of little help. Radioisotope scanning is of fundamental importance and has an implication in histology. Ultrasonography has a diminishing role although its use has led to the widespread acceptance of needle aspiration. Needle aspiration cytology is now the most important maneuver in preoperative assessment and management of the goiter patient. Its results permit refined operative selection, the institution of safe conservative management, and greater organization in surgical treatment. Persistent cooperation between clinician and pathologist can yield a high rate of reliable preoperative cytological diagnosis obtained by needle aspiration.

ISSN:0022-4790    

DOI:10.1002/jso.2930160307

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1981

数据来源: WILEY

摘要:

AbstractThe discovery of functioning metastases of thyroid carcinoma and their appropriate treatment with radioiodine are the keys to long‐term survival. Functioning metastases can be adequately found only if postsurgical residual normal thyroid tissue is ablated and total body scanning performed. Radioiodine treatment of functioning metastases following appropriate surgery is the treatment of choice, and long‐term follow‐up with total body scanning techniques is most impo

ISSN:0022-4790    

DOI:10.1002/jso.2930160308

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1981

数据来源: WILEY

ISSN:0022-4790    

DOI:10.1002/jso.2930160309

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1981

数据来源: WILEY

摘要:

AbstractSide‐effects to levamisole given as adjuvant to surgery in a consecutive series of 203 neoplastic patients are reported: Thirty‐four patients (16.7%) suffered gastric adverse reactions; 8 (3.9%) allergic; 6 (2.9%) intestinal; 6 (2.9% neurologic; 4 (1.9%) severe hyperthermia (more than 40.5°C); 3 (1.4%) flu‐like illness; 1 (0.4%) leucopenia; and 1 (0.4%) agranulocytosis. Withdrawal rate was 5.4% or 11 patients. Side effects appeared sex‐related (39.0% in females, 17.7% in males; with seven female dropouts out of 11), unrelated to other eventual adjuvant treatments, and reappearing at a new challenge with levamisole. The opportunity of very close control of patients taking levamisole for at least the first months is d

ISSN:0022-4790    

DOI:10.1002/jso.2930160310

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1981

数据来源: WILEY

摘要:

AbstractTwo Nb rat prostatic adenocarcinomas, 13 Pr‐12, an autonomous tumor, and 2 Pr‐128, an androgen‐dependent tumor, were transplanted into groups of congenitally athymic nude mice. The agents used for treatment of these tumors are agents characteristically not used in treatment of prostatic adenocarcinoma in humans. However, these have been efficacious in treating other solid malignancies. Both agents, BCNU and Actinomycin‐D, were efficacious in producing tumor regression and in causing at least a temporary decrease in tumor growth. The combination of the Nb rat prostatic adenocarcinoma model and nude mouse is presented as an appropriate system to screen therapeutic agents that have proved efficacious in treatment of other solid malignancies but have not been used in treating prostatic adenoca

ISSN:0022-4790    

DOI:10.1002/jso.2930160311

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1981

数据来源: WILEY