ISSN:0022-4790    

DOI:10.1002/jso.2930230202

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1983

数据来源: WILEY

摘要:

AbstractA case of Ewings sarcoma arising in the soft tissue of the thumb is described. This appears to be the first case of digital extraskeletal Ewings sarcoma. The soft tissue location, the primary rather than metastatic nature, and the tumor type in this case were well documented.

ISSN:0022-4790    

DOI:10.1002/jso.2930230203

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1983

数据来源: WILEY

摘要:

AbstractThe charts of 285 patients diagnosed as metastatic cancer from an undetermined primary site were reviewed. An attempt was made to characterize this disease entity more specifically, and to evaluate the various modes of therapy utilized in such patients. Adenocarcinoma is the most common histologic type overall; squamous cell carcinoma is most common in 5‐year survivors. Lymph nodes are the most common metastatic site overall and in 5‐year survivors. The mean overall survival is 8.69 months with 8.7% 2‐year survivors and 2.8% 5‐year survivors. Surgery alone, radiation alone or in combination, and chemotherapy alone or in combination were utilized in these patients with 5‐year survivals of 11, 3.7, and 1.1%, respectively. The 5‐year survivors all had therapy initiated immediately after histologic diagnosis and medical workup, and all of their tumors were less than 8 cm in diameter. In view of this data, patients with metastatic cancer from an undetermined primary site should always be considered for early, aggress

ISSN:0022-4790    

DOI:10.1002/jso.2930230204

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1983

数据来源: WILEY

摘要:

AbstractFifty‐one of 256 patients underwent a palliative procedure for advanced carcinoma of the stomach (TNM stage IV). The resection was classified as palliative if metastatic disease was left behind in the lymph nodes, if involvement of organs elsewhere in the abdominal cavity was present, or if microscopy revealed tumor tissue in the resection lines. Twenty‐six patients underwent a resection for palliation. There were 14 total and 12 partial gastrectomies. There were 2 deaths after total gastrectomy because of anastomotic leakage. The mean survival time after operation was 9.5 months. In 13 patients (50%) palliation was good with preoperative symptomatic relief without initiating new symptoms, acceptable body weight, and solid food intake. In 7 patients (27%) palliation was moderate, and in 4 (15%) poor. The results after gastroenterostomy in 25 patients were poor. The study shows that palliative total and partial gastrectomy can produce palliation in advanced gastric can

ISSN:0022-4790    

DOI:10.1002/jso.2930230205

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1983

数据来源: WILEY

摘要:

AbstractA product, Osto‐Zyme, was clinically tested at our Institute for the elimination of odor. Thirteen clients were chosen by enterostomal therapists to be tested. The product was sprayed directly into pouch, peristomal skin, and into night drainage units. This product proved very effective in the elimination of odor. The manufacturer of Osto‐Zyme is the Richard C. Shelton Co., Wright Brothers Branch, Dayton, O

ISSN:0022-4790    

DOI:10.1002/jso.2930230206

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1983

数据来源: WILEY

摘要:

AbstractComputed tomography (CT) has shown to be of great value in the treatment of cancer with radiation therapy. It is used more and more in the estimation of tumor volume and for treatment planning, with the aid of the computerized treatment unit. At the James Graham Brown Cancer Center, Department of Radiation Oncology, CT has been used routinely for the treatment planning. From October 1, 1981 to June 30, 1982, we performed 180 CT scans for the treatment planning, 380 simple dose calculations, 237 complex treatment plans, and 42 intracavitary dosimetry using the treatment planning unit. This is a review of our experience with some illustrations. Accurate tumor dose can be delivered with reducing the complications with the use of CT and the computerized treatment unit.

ISSN:0022-4790    

DOI:10.1002/jso.2930230207

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1983

数据来源: WILEY

摘要:

AbstractAlthough abdominal metastasis from lung cancer are not unusual postmortem findings, they are rarely of clinical significance. Our patient's clinical course was complicated by intestinal obstruction secondary to metastatic lung cancer. With the current epidemic of lung cancer, we can expect more patients with abdominal complaints secondary to metastatic disease. In these patients, survival time averaged less than 60 days.

ISSN:0022-4790    

DOI:10.1002/jso.2930230208

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1983

数据来源: WILEY

摘要:

AbstractTransformation of well‐differentiated thyroid adenocarcinoma to anaplastic cancer has been occasionally reported. Two new cases of such transformation are now described. The time interval from diagnosis to the development of anaplastic cancer was 15 years in the first patient and 10 years in the second. Both patients ultimately developed extensive bilateral pulmonary metastases and died within 6 months from the diagnosis of the transformation. Hypotheses concerning the pathogenesis of the transformation and the literature were reviewed. We believe that histopathological confirmation of recurrent and rapidly progressive thyroid tumors is necessary prior to initiation of therap

ISSN:0022-4790    

DOI:10.1002/jso.2930230209

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1983

数据来源: WILEY

摘要:

AbstractTwenty‐six patients with adenocarcinomas of the rectum, rectosigmoid, or sigmoid colon given adjuvant pre‐ or postoperative pelvic radiation therapy followed at least 5 years were retrospectively reviewed to evaluate late tumor control and complication rates. The overall 7‐year survival rate was 80 ± 8% with B2,3, patients faring better than C2,3(94 ± 6% versus 43 ± 19%, p<0.005). Local pelvic tumor control was achieved in 23/26 patients (88%); patients with high‐stage (C2,3) or poorly‐differentiated adenocarcinomas had a higher postirradiation pelvic relapse rate (3/11) versus low stage, well or moderately‐well differentiated tumors (0/15). A major complication (none fatal) occurred in 2 of 26 patients (8%) and was not correlated with either irradiation dose nor volume.Long‐term follow‐up is now available on patients who received adjuvant pelvic irradiation for rectal or sigmoid carcinomas and indicates a high pelvic tumor control rate. The 8% major complication rate may be decreased in the future by more sophisticated irradiation

ISSN:0022-4790    

DOI:10.1002/jso.2930230210

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1983

数据来源: WILEY

摘要:

AbstractRecent advances in the biology of the epidermis increase our understanding of skin cancer. Epidermal tissue culture demonstrates that cells from epidermal malignancies retain their malignant characteristics. Some epidermal tumors contain a low molecular weight keratin as a major structural protein; a low molecular weight keratin is a characteristic of fetal epidermis as well. Certain epidermal cell‐surface antigens, such as the pemphigus antigen, may be absent in skin cancers. A population of long‐lived skin cells may be the site for genetic alterations that eventually produces skin cancers. A population of basal “dark” cells is increased after treatment with tumor promoting agents such as phorbol esters. Two‐stage (initiation, promotion) epidermal carcinogenesis can now be studied in tissue culture. Several components of the complex multilayered basement membrane zone are produced by epidermal cells. Malignancies of epidermal cells may extend beyond the basement membrane zone by disordered synthesis of the zone or by producing enzymes including collagenases that alter

ISSN:0022-4790    

DOI:10.1002/jso.2930230211

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1983

数据来源: WILEY