摘要:

We measured autofluorescence of the macula with fluorophotometry to evaluate age-related changes in human retinal pigment epithelium. Examined in this study were 35 aphakic eyes of 25 patients, ranging in age from 52 to 87 years, after uneventful intracapsular cataract extraction and 21 normal phakic eyes of 20 patients, ranging in age from 9 to 29 years. Autofluorescence at the macula of aphakic eyes increased in an age-dependent manner (r = 0.514; p < 0.01) as follows: 15.0 ngEq/ml for the sixth decade (n = 1), 17.2 ± 4.2 for the seventh decade (n = 11), 21.3 ± 3.6 for the eighth decade (n = 16) and 24.6 ± 2.7 for the ninth decade (n = 7). We believe that the autofluorescence originates mainly from lipofuscin in the retinal pigment epithelium, and that the autofluorescence enhanced with age reflects the accumulation of lipofuscin.

ISSN:0030-3755    

DOI:10.1159/000310027

出版商:S. Karger AG    

年代:1989

数据来源: Karger

摘要:

Metastasis directly to the optic nerve head without choroidal involvement is rare. We report a case of metastatic adenocarcinoma of the optic nerve head and retina with vitreous seeds which was observed in a 45-year-old Japanese male. The primary site of the lesion was clinically the upper lobe of the left lung. Tumor emboli were observed in the central retinal vein. Vitreous seeds appeared to have arisen from a necrotic area and papillary projections of the tumor.

ISSN:0030-3755    

DOI:10.1159/000310028

出版商:S. Karger AG    

年代:1989

数据来源: Karger

ISSN:0030-3755    

DOI:10.1159/000310029

出版商:S. Karger AG    

年代:1989

数据来源: Karger