摘要:

The clinical history and the pathohistological findings of both eyes of a homosexual man with AIDS and cytomegalovirus (CMV) infection are reported. A CMV panuveitis with cytomegalic transformation of vascular endothelium was present in the posterior and anterior uvea as well as a typical CMV retinitis. In addition, a CMV infection of smooth muscle cells in the iris and ciliary body as well as of endothelial cells of the cornea and the aqueous drainage system were found for the first time.

ISSN:0030-3755    

DOI:10.1159/000309939

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

The patient, who is now 60, had a nevus and areas of cystic changes in the conjunctiva in her right eye, which had been present from birth to the age of 59. In 1987, rapid tumor growth aroused suspicion that malignant change could be occurring and so the nevus as well as the area of the conjunctiva containing cystic changes were excised. Histological finding: conjunctival malignant melanoma, containing compressed (densely arranged) atypical cells with pleomorphic hyperchromatic nuclei and prominent nucleoli. The biopsy specimen of the conjunctiva showed a typical nevocellular nevus with large inclusion cysts of the conjunctival epithelium.

ISSN:0030-3755    

DOI:10.1159/000309940

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

20 eyes of 11 patients suffering from most severe eye burns of grade 4 or worse were treated in addition to various other drugs with epiderm growth factor (EGF) or placebo in a double-blind test. Among 10 eyes treated with EGF, 6 achieved complete regeneration of the corneal epithelium, and 1 additional case, of the conjunctival epithelium. Among the eyes receiving placebo, only 3 out of 10 healed; all of them were also treated with fibronectin. Although in these very difficult cases EGF could not be investigated as a single therapy, and various other undefined factors may have been effective, in the extended course of the disease the period of EGF treatment was marked by a significant better regeneration of the epithelium.

ISSN:0030-3755    

DOI:10.1159/000309941

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

Six persons with retinitis pigmentosa and exudative vasculopathy were observed within a group of 110 patients with retinitis pigmentosa seen during 5 years. Two new hypotheses are formulated in order to explain the origin of this relationship.

ISSN:0030-3755    

DOI:10.1159/000309942

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

Detection of inflammatory lesions of the optic nerve by magnetic resonance imaging requires a special imaging technique. In 3 patients with persisting visual loss due to retrobulbar neuritis we scanned the optic nerve with a short inversion recovery sequence. In each of the 3 patients magnetic resonance imaging revealed inflammatory lesions in the intracanalicular portion of the optic nerve. It is supposed that the unfavorable location of the lesions in the optic canal is responsible for the poor recovery of visual acuity. In another patient with a bilateral optic nerve atrophy demyelination of the optic nerve could be made visible.

ISSN:0030-3755    

DOI:10.1159/000309943

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

Cystic fibrosis is characterized by an abnormally high electrolyte concentration in exocrine secretions. The authors performed the tear mucus ferning test in 26 eyes of children with cystic fibrosis and compared the results to those in an equal number of age-matched normals. The results suggest that the increased electrolyte concentration could be responsible for the increased hyperviscosity of mucus. The tear mucus ferning test appears to be a suitable diagnostic test for the assessment of cystic fibrosis.

ISSN:0030-3755    

DOI:10.1159/000309944

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

Using electron microscopy, we examined an eye obtained at autopsy in which a C-loop intraocular lens had been implanted into the posterior chamber 2 years and 4 months prior to the patient’s death. The lens was affixed with the superior loop outside the capsular bag and the inferior loop within the capsular bag. The two ciliary epithelial layers to which the superior loop was attached were thinned; the pigmented epithelial layer was completely absent and the nonpigmented epithelial layer was disrupted, suggesting breakdown of the blood-aqueous barrier. Proliferating lens epithelial cells, basement membrane-like material, collagen fibers and microfibrils were seen surrounding the inferior loop. The lens capsule, the zonular fibers and the ciliary epithelium adjacent to the inferior loop showed no pathological changes.

ISSN:0030-3755    

DOI:10.1159/000309945

出版商:S. Karger AG    

年代:1988

数据来源: Karger

ISSN:0030-3755    

DOI:10.1159/000309946

出版商:S. Karger AG    

年代:1988

数据来源: Karger

ISSN:0030-3755    

DOI:10.1159/000309947

出版商:S. Karger AG    

年代:1988

数据来源: Karger

ISSN:0030-3755    

DOI:10.1159/000309948

出版商:S. Karger AG    

年代:1988

数据来源: Karger