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1. |
No Widespread Psychological Effect of the Fragile X Premutation in Childhood: Evidence from a Preliminary Controlled Study |
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Journal of Developmental & Behavioral Pediatrics,
Volume 22,
Issue 6,
2001,
Page 353-359
GWEN MYERS,
MICHÈLE MAZZOCCO,
ANNE MADDALENA,
ALLAN REISS,
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摘要:
This study was designed to examine the effect of the fragile X premutation (pM) on cognitive function and behavior. Participants included 14 children (7 males, 7 females) with the fragile X pM and 14 children without the fragile X pM (and without the fragile X full mutation [fM]), each of whom was matched by age and gender with one of the participants from the pM group. The children ranged in age from 3 years, 1 month, to 17 years, 11 months. Participants were individually administered measures of intellectual functioning, academic achievement, and visual motor integration. Parent rating scales of problem behaviors were completed. Group differences were examined using nonparametric statistics. No statistically significant differences were found between the premutation and nonpremutation groups. The results from this study are consistent with the hypothesis that the premutation does not, in general, have an effect on a child's development. However, this does not preclude cases where specific factors may lead to a specific phenotype.
ISSN:0196-206X
出版商:OVID
年代:2001
数据来源: OVID
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2. |
Parental Influence on Children: Baseball at the Kearns House |
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Journal of Developmental & Behavioral Pediatrics,
Volume 22,
Issue 6,
2001,
Page 359-359
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ISSN:0196-206X
出版商:OVID
年代:2001
数据来源: OVID
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3. |
Psychosocial Development in Adolescents with Turner Syndrome |
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Journal of Developmental & Behavioral Pediatrics,
Volume 22,
Issue 6,
2001,
Page 360-365
ELIZABETH,
MCCAULEY PENELOPE,
FEUILLAN HARVEY,
KUSHNER JUDITH,
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摘要:
Turner syndrome is a genetic condition in which part or all of the second X chromosome is missing. Our goal in this study was to examine the psychosocial adjustment of a sample of adolescent girls with Turner syndrome. Subjects included 122 girls with a diagnosis of Turner syndrome (TS) and a control group of 108 girls with no genetic disorder or chronic illness. Subjects were 13 to 18 years of age. A battery of questionnaires assessing social, academic, school, and behavioral functioning was administered. TS girls were seen as having significantly more problems in terms of social relationships and school progress and were more likely to meet criteria for attention-deficit hyperactivity disorder than control girls. The TS girls were also rated by a parent as less socially competent (e.g., fewer friends, less time with friends) than the control group. Social difficulties appear to be an area of vulnerability for TS girls. Counseling individuals with Turner syndrome and their families about the need to carefully develop and nurture social skills and relationships may prove useful in advancing the social adaptation of these young women.
ISSN:0196-206X
出版商:OVID
年代:2001
数据来源: OVID
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4. |
Differential Patterns of Development: The Interaction of Birth Weight, Temperament, and Maternal Behavior |
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Journal of Developmental & Behavioral Pediatrics,
Volume 22,
Issue 6,
2001,
Page 366-375
KATHLEEN,
GORMAN ANDREA,
LOURIE NASEEM,
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摘要:
A short-term longitudinal study of 83 families compared patterns of development between full-term small for gestational age (SGA) and normal birth weight (NBW) infants. Data were collected on infant temperament and maternal interaction at 3 and 6 months, and infant developmental outcomes at 6 months in order to investigate relationships between infant and maternal behavior, and developmental outcomes as a function of birth weight. Findings revealed few differences between SGA and NBW groups. However, the relations between infant temperament and maternal behavior varied as a function of birth weight and home environment. Specifically, more positive home environments were associated with higher ratings of maternal behavior and lower levels of infant negative reactivity for SGA but not for NBW infants. In addition, higher negative reactivity was related to lower performance on both the mental and psychomotor scales of the Bayley Scales of Infant Development (BSID), with stronger associations reported for SGA infants than for NBW infants.
ISSN:0196-206X
出版商:OVID
年代:2001
数据来源: OVID
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5. |
The Influence of Etiology and Treatment Factors on Intellectual Outcome in Congenital Hypothyroidism |
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Journal of Developmental & Behavioral Pediatrics,
Volume 22,
Issue 6,
2001,
Page 376-384
SOON-IL,
SONG DENIS,
DANEMAN JOANNE,
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摘要:
To determine the effects of hypothyroidism and hormonal patterns on outcome, we tested 65 7- to 12-year-old children with congenital hypothyroidism using standardized tests of intelligence, neuropsychological functioning, memory, and achievement. Results were analyzed by etiology, time to thyrotropin normalization, and hormone levels at testing. Children with athyreosis scored below other etiologies on visuospatial, attention, and arithmetic indices. Children whose thyroid-stimulating hormone levels normalized by 1 to 2 months of age scored higher than later normalizers on indices of visual memory, attention, and arithmetic. Normalization of thyroid-stimulating hormone by 3 months of age was associated with better memory and learning abilities than later normalization. Thyroid hormone levels at testing were correlated with indices of sensorimotor, spatial, and language abilities. Two children with persistently elevated thyrotropin levels were not adversely affected. Present findings signify the need to establish etiology, normalize thyrotropin early, and maintain hormone levels in the normal range throughout childhood in children with congenital hypothyroidism.
ISSN:0196-206X
出版商:OVID
年代:2001
数据来源: OVID
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6. |
Effects of Colostrum in Newborn Humans: Dissociation Between Analgesic and Cardiac Effects |
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Journal of Developmental & Behavioral Pediatrics,
Volume 22,
Issue 6,
2001,
Page 385-390
ELLIOTT,
BLASS LISA,
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摘要:
This study evaluates the effects of colostrum, delivered via syringe or on a pacifier, on the pain and heart rate reactions of newborns undergoing routine heel-lance. This was achieved by following a quasi-randomized, controlled trial in which 60 newborn infants at Boston Medical Center, Boston, MA, were randomly assigned to receive colostrum, sucrose, or water, by syringe or on a pacifier, for a total of 6 groups (n = 10 per group). The effectiveness of an intervention was determined by comparing crying, grimacing, and heart rate differences among groups during and following blood collection. We report that colostrum, delivered by syringe or on a pacifier, did not reduce crying or grimacing relative to control infants who received water. As has been previously reported, sucrose markedly reduced both crying and grimacing, and attenuated the rise in heart rate that normally accompanies blood collection (p< .002). Water, via syringe or on a pacifier, did not prevent the increase in heart rate, nor did colostrum via syringe. In contrast, colostrum delivered on a pacifier prevented the increase in heart rate despite pain reactivity and extreme crying. The implications of this dissociation are discussed.
ISSN:0196-206X
出版商:OVID
年代:2001
数据来源: OVID
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7. |
Maternal Feeding Practices and Beliefs and Their Relationships to Overweight in Early Childhood |
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Journal of Developmental & Behavioral Pediatrics,
Volume 22,
Issue 6,
2001,
Page 391-408
AMY,
BAUGHCUM SCOTT,
POWERS SUZANNE,
JOHNSON LEIGH,
CHAMBERLIN CINDY,
DEEKS ANJALI,
JAIN ROBERT,
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摘要:
To better explore possible factors that may lead to childhood obesity, we developed and analyzed two new instruments that assess maternal feeding practices and beliefs. The Infant Feeding Questionnaire (IFQ) assesses feeding during the entire first year of life and was administered to 453 mothers of children 11 to 23 months old. The Preschooler Feeding Questionnaire (PFQ) assesses feeding of young children between the ages of 2 to 5 years and was administered to 634 mothers of children this age. Each questionnaire was factor analyzed and mean factor scores were calculated and linked with the children's measured and mothers' self-reported weight and height. Mean factor scores from the IFQ and PFQ were compared between mothers who were obese (body mass index ≥30 kg/m2) and those who were nonobese, between those who did and those who did not have an overweight child (weight-for-height ≥90th percentile), and between those who had a low income (≤185% of the poverty level) and those who had a high income. To control for confounding variables and to detect interaction among variables, hierarchical linear regression was used. Results from this study did not suggest that there is a particular "feeding style" that is associated with overweight in young children; however, there were differences found in feeding behaviors between high and low income mothers.
ISSN:0196-206X
出版商:OVID
年代:2001
数据来源: OVID
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8. |
The Behavioral Phenotype in Fragile X: Symptoms of Autism in Very Young Children with Fragile X Syndrome, Idiopathic Autism, and Other Developmental Disorders |
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Journal of Developmental & Behavioral Pediatrics,
Volume 22,
Issue 6,
2001,
Page 409-417
SALLY,
ROGERS ELIZABETH,
WEHNER RANDI,
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摘要:
This study was designed to explore the behavioral phenotype of autism in a group of young children with fragile X syndrome (FXS). Twenty-four children with FXS, ages 21 to 48 months, were compared with two well-matched groups: 27 children with autism (AD) and 23 children with other developmental delays (DD), on two standardized autism instruments, as well as on measures of development and adaptive behavior. Two FXS subgroups emerged. One subgroup (n = 16) did not meet study criteria for autism. Their profiles on the autism instruments and the developmental instruments were virtually identical to the other DD group. The other FXS subgroup (n = 8, or 33% of the total FXS group) met study criteria for autism. Their profiles on the autism instruments were virtually identical to the group with autism. The finding of two FXS subgroups raises a hypothesis of additional genetic influences in the FXS autism group, warranting further genetic studies.
ISSN:0196-206X
出版商:OVID
年代:2001
数据来源: OVID
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9. |
Learning About Pain in Preterm Newborns |
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Journal of Developmental & Behavioral Pediatrics,
Volume 22,
Issue 6,
2001,
Page 418-424
NATHALIE,
GOUBET RACHEL,
CLIFTON BHAVESH,
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摘要:
The first goal of the study was to explore whether preterm newborns can learn to predict painful stimulation. The second goal was to provide a description of physiological and behavioral responses to repeated heel-sticks over days. Preterm newborns, born between 28 and 32 weeks gestational age, were observed five times over a period of 2 weeks while undergoing heel-sticks. Infants' facial expressions, cardiac reactions, and movement durations were recorded before, during, and after the heel-stick procedure. On Tests 1, 3, and 5, the phlebotomist picked up the baby's leg and held it for 10 seconds before proceeding to the heel-stick. Infants showed significantly greater increase in heart rate during the leg pickup on Test 5 compared with Test 1. This increase in heart rate after 2 weeks of experience suggests that newborn infants learned to anticipate the painful stimulus. Infants also demonstrated reliable behavioral and cardiac reactions to the invasive part of the heel-stick, but no change was observed in reactivity over days. However, greater post-conceptional age (PCA) was associated with increased behavioral reactivity during heel-stick on Tests 4 and 5. The anticipatory heart rate increase during leg pickup highlights the preterm infant's early capacity to learn and react to experience in the neonatal intensive care unit. The lack of global change in reactivity to the invasive procedure over days illustrates the need to take into account specific factors such as PCA when investigating sensitivity to repeated pain experiences.
ISSN:0196-206X
出版商:OVID
年代:2001
数据来源: OVID
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10. |
Preparing a 3 Year Old and His Parents for an Elective Surgery |
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Journal of Developmental & Behavioral Pediatrics,
Volume 22,
Issue 6,
2001,
Page 425-429
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摘要:
Billy's pediatrician discovered an inguinal hernia and referred him to a pediatric surgeon for a herniorrhaphy. Plans were made for an elective surgery. The pediatrician then received a call from Billy's mother. Although she agreed that Billy (3 years old) needed the procedure, his mother inquired about the risk of general anesthesia. "I heard that some children have a horrible time when they are given anesthesia." She also read about some parents present at the time an anesthesia is given to a child. "Can I be with Billy when he goes to surgery?" In addition, after talking to several parents, she heard that the immediate postoperative period can be difficult for some children. She asked, "Wouldn't it make sense for me to be with Billy when he wakes up after surgery? I'd like to comfort him and let him know that I am there with him."The pediatrician, only a few years from her training, was comfortable answering the first question but was uncertain about a response to the latter two questions. She considered reviewing the literature in this area and investigating local options.
ISSN:0196-206X
出版商:OVID
年代:2001
数据来源: OVID
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