摘要:

AbstractExpression ofc‐fosimmunoreactivity was investigated in rat brain after unilateral application of a weak anodal direct current (anodal polarization) to the sensorimotor cortex of rats. Increases in Fos‐immunopositive neurons were observed transiently in the neocortex, cingulate cortex, piriform cortex, and hippocampal formation, which were ipsilateral to the polarization, as a function of the duration and intensity of the currrent applied. It is likely that anodal polarization enhances the neuronal activities in the cortex dependent on polarization paradi

ISSN:1323-1316    

DOI:10.1111/j.1440-1819.1995.tb01905.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

摘要:

AbstractWe investigated the effects of human corticotropin‐releasing hormone (hCRH) on the sleep structure and body temperature rhythms of seven healthy young men. Polysomnographic recordings were obtained and body temperatures were monitored continuously for 48 h in each subject following the intravenous administration of saline or of 100 μg hCRH. The administration of hCRH was associated with a significant phase‐advancement in body temperature rhythmvsthe saline control. The administration of hCRH affected non‐rapid eye movement (NREM) sleep by reducing significantly slow wave sleep (SWS) and sleep efficiency, whereas the percentage of sleep stages 1 and 2 were increased significantly. These changes in body temperature rhythms and sleep structure induced by hCRH resembled those observed in patients with endogenous depression, except for the findings during rapid eye movement (REM) sleep. We hypothesize that a hypersecretion of hCRH in patients with endogenous depression may help to explain the changes in body temperature rhythms and sleep structure often reported in such pa

ISSN:1323-1316    

DOI:10.1111/j.1440-1819.1995.tb01906.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

摘要:

AbstractA 32 year old male patient suffered from recurrent hypersomnia for 12 years was successfully treated with vitamin B12. Episodes of hypersomnia lasting a few days occurred repeatedly a few times each year. Furthermore, the frequency of episodes had increased during the last 2 years. During the administration of vitamin B12, the patient had no episodes of hypersomnia for 6 months. In addition, he did not have any episodes during a follow‐up observation period of 17 months after cessation of the treatment. Thus, this case suggests that vitamin B12may be effective for preventing recurrent hypersomni

ISSN:1323-1316    

DOI:10.1111/j.1440-1819.1995.tb01907.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:1323-1316    

DOI:10.1111/j.1440-1819.1995.tb01909.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:1323-1316    

DOI:10.1111/j.1440-1819.1995.tb01892.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:1323-1316    

DOI:10.1111/j.1440-1819.1995.tb01893.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:1323-1316    

DOI:10.1111/j.1440-1819.1995.tb01894.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY