ISSN:1323-1316    

DOI:10.1111/j.1440-1819.1989.tb02922.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

ISSN:1323-1316    

DOI:10.1111/j.1440-1819.1989.tb02923.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

ISSN:1323-1316    

DOI:10.1111/j.1440-1819.1989.tb02924.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

Abstract:Positron emission tomography (PET) was performed with the18F‐fluoro‐deoxy‐glucose method on 29 patients with epilepsy (generalized epilepsy, 4; partial epilepsy, 24; undetermined type, 1). The subjects were restricted to patients with epilepsy without focal abnormality on X‐CT. All the patients with generalized epilepsy showed a normal pattern on PET. Fourteen out of the 24 patients with partial epilepsy and the 1 with epilepsy of undetermined type showed focal hypometabolism on PET. The hypomeiabolic zone was localized in areas including the temporal cortex in 11 patients, frontal in 2 and thalamus in 1. The location of hypometabolic zone and that of interictal paroxysmal activity on EEG were well correlated in most patients. The patients with poorly controlled seizure showed a higher incidence of PET abnormality (12 out of 13) than those with well‐controlled seizures (2 out of 11). The incidence of abnormality on PET and MRI and the location of both abnormalities were not necessarily coincident. These results indicated that the PET examination in epilepsy provides valuable information about the location of epileptic focus, and that the findings on PET in patients with partial epilepsy may be one of the good indicators about the intractability of partial epilepsy, and that PET and MRI provide complementary information in the diagnosis of

ISSN:1323-1316    

DOI:10.1111/j.1440-1819.1989.tb02925.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

ISSN:1323-1316    

DOI:10.1111/j.1440-1819.1989.tb02926.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

Abstract:Magnetic resonance imaging (MRI) and computed tomography (CT) were performed on 45 patients with intractable complex partial seizures. MRI was performed with a super conducting whole‐body scanner operating at 0.5 tesla (T) and 1.5 T. In patients with temporal lobe epilepsy, 8 of 24 patients had abnormal CT, but 16 of 24 patients showed abnormal MRI. 1.5 T MRI detected more abnormality than 0.5 T MRI when CT was normal. In patients with frontal lobe epilepsy, 5 of 7 patients had normal CT and MRI. In 2 other patients, MRI demonstrated an arachnoid cyst and increased signal intensity area on the T2‐weighted images, which were not detected by CT. In patients with occipital lobe epilepsy, 5 of 6 patients show abnormal CT and MRI. In patients with tuberous sclerosis, MRI revealed some increased signal intensity areas on the T2‐weighted images in the occipital and temporal lobe, which were not detected by CT. Most surface EEG foci corresponded with the side of MRI abnormality. These data indicate that MRI is more informative than CT in complex partial seizures. MRI is the imaging technique of choice in the diagnosis of complex partial sei

ISSN:1323-1316    

DOI:10.1111/j.1440-1819.1989.tb02927.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

SUMMARYWe reported two kinds of dynamic topographies. In one, an inters pike interval histogram and a computerized topography of the EEG basic activity were composed. In the other, spike and sharp wave characteristics were composed of an isopotential topography. These topographies enabled us to observe serial changes in epileptic discharge dynamically by 1 msec.

ISSN:1323-1316    

DOI:10.1111/j.1440-1819.1989.tb02928.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

Abstract:In 31 patients with temporal lobe epilepsy, the precise site of epileptogenic focus was determined by means of a depth EEG recording as one of the presurgical evaluations. In 13 patients, a CT scan revealed focal lesions; 7 in the left temporal lobe and 6 in the right temporal lobe. In 5 of the 7 patients and in 5 of the 6 patients the epileptogenic foci were determined in the temporal lobe on the side of a CT lesion. However, in 2 of the patients with a CT lesion in the left temporal lobe, independent epileptogenic foci were found in both the temporal lobes, and in the other patient with a CT lesion in the right temporal lobe, they were found in the right frontal and left temporal lobes. Thus, the CT lesions agreed in lateralikeation and focality with the epileptogenic foci in 10 of the 13 patients (77%), but they disagreed in 3 (23%). A CT lesion disclosed in the temporal lobe does not necessarily indicate the side and/or site where the epileptogenic focus may be localized. Although exceptions may be made, spatial disagreement was exemplified between the CT lesion and epileptogenic focus. Therefore, extreme caution has to be taken on the side and/or site of the epileptogenic focus when functional surgical indication is to be made.

ISSN:1323-1316    

DOI:10.1111/j.1440-1819.1989.tb02929.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

ISSN:1323-1316    

DOI:10.1111/j.1440-1819.1989.tb02930.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

SUMMARY123I‐ZMP‐SPECT scans at the interictal stages in 13 epileptic patients with normal X‐ray CT findings were reexamined at intervals of 1.9 ± 0.8 years. Interictal scalp EEGs were recorded a few hours after each SPECT scan. All of the SPECT abnormalities indicated focal hypo fixation images of123I‐IMP, i.e. zones of a decreased rCBF reflecting a functional inactivation. Among 11 patients with the SPECT abnormalities in the first SPECTs, eight cases had the complete or partial regional reproduction of the abnormalities in the second SPECTs. As changes in the SPECT findings, an alteration from the abnormal SPECT

ISSN:1323-1316    

DOI:10.1111/j.1440-1819.1989.tb02931.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY