ISSN:1323-1316    

DOI:10.1111/j.1440-1819.1965.tb00038.x

出版商:Blackwell Publishing Ltd    

年代:1965

数据来源: WILEY

摘要:

SummaryThe case histories and anatomic alterations of two patients with the lumbosacral leg‐thigh type of spinal progressive muscular atrophy are presented. The course of the diseese was very rapid, and the patients died of bulbar palsy in 7 months (first case) and 18 months (second case), respectively.Cutaneous sensation was normal and pyramidal signs were not elicited in both cases. Electromyogram and biopsy specimens showed characteristic changes of lower motor neuron damage. Pathological examination revealed degeneration of the anterior horn cells with marked decrease in their numbers and demyelination of anterior roots. The giant pyramydal cells of Betz and pyramydal pathways were, nevertheless, intact. The second case generally demonstrated myasthenic syndrome clinically, and dystrophic changes of muscle fibers on pathological studies.There have been three clinical pictures simulating the lumbosacral leg‐thigh type of spinal progressive muscular atrophy. They are all atypical amyotrophic lateral sclerosis; the leg‐thigh form without spastic phenomena (Kahler, 1884), the pseudo‐polyneuritic form (Marie et Patrikios, 1918), and the peroneal form (Hemmer, 1951). Their characteristic findings were compared clinicopathologically with our tw

ISSN:1323-1316    

DOI:10.1111/j.1440-1819.1965.tb00039.x

出版商:Blackwell Publishing Ltd    

年代:1965

数据来源: WILEY

摘要:

SummaryFive cases of proximal occlusion and stenosis of the anterior cerebral artery being examined by the bilateral angiographic studies are reported. One case is non‐paralytic and four cases are paralytic. In the paralytic group three fourth of the cases involved upper‐extremities.The cases with a rather long history and remarkable dilatation of lateral ventricle show clinically psychiatric symptoms, such as dementia and confusion, but the case with a rather short history shows no ventricle dilatation.The bilateral carotid angiograms with each contralateral carotid compression are needed for exact diagnosis and also differentiation of the occlusion and the stenosis of the proximal portion of anterior cerebral artery.Proximal occlusion and stenosis of the anterior cerebral artery were discussed with five cases and the referen

ISSN:1323-1316    

DOI:10.1111/j.1440-1819.1965.tb00040.x

出版商:Blackwell Publishing Ltd    

年代:1965

数据来源: WILEY

ISSN:1323-1316    

DOI:10.1111/j.1440-1819.1965.tb00041.x

出版商:Blackwell Publishing Ltd    

年代:1965

数据来源: WILEY

摘要:

Summary1. Due to liver injury induced by carbon tetrachloride, the activities of GPT, GOT, arginase, tryptophan pyrrolase and δ4‐‐3‐ketosteroid reductase in rat liver and the ability of rat liver to inactivate estrogen decreased, while the activities of GPT and GOT in the brain were inversely increased. Decrease in the activities of GPT, GOT and arginase in the liver and the ability of the liver to inactivate estrogen were also to be brought on by forced running or immobilization.2. LSD increased the activity of hexokinase in the brain, but it had no effect on the enzyme activities of the liver or on estrogen inactivation by the liver.3. Stress conditions such as forced running, immobilization, exposure to cold, and the administration of chlorpromazine significantly increased the activity of tryptophan pyrrolase in rat liver. Removal of the adrenals did not affect the increase of enzyme activity, but ‘hypophysectomy’ completely abolished the enzyme

ISSN:1323-1316    

DOI:10.1111/j.1440-1819.1965.tb00042.x

出版商:Blackwell Publishing Ltd    

年代:1965

数据来源: WILEY

摘要:

SummaryEvoked potentials to the splanchnic stimulation were recorded from the ipsi‐lateral posterior funiculus and from the bilateral anterolateral funiculi in the spinal cord. The former had a short latency and the latter had a long latency. Evoked potentials of the splanchnic nerve were recorded from the nucleus cuneatus and lemniscus medialis in the medulla, which had a short latency since their origin was in the impulses ascended through the posterior funiculus of the spinal cord. Evoked potentials were also recorded from the tractus spino‐m‐thalamicus and nucleus reticularis ventralis in the medulla, which had a long latency corresponding with those from the anterolateral funiculi of the spinal cord.The splanchnic impulse, ascended through the anterolateral funiculus of the spinal cord, was influenced by the effect of the vagal stimulation as well as the stimulation of the somatosensory and proprioceptive systems through mediation of the activity of the brain stem reticular formation. The vagal stimulation also exerted an inhibitory effect on the splanchnic afferent impulse in the anterolateral funiculus through some other mechanism than mediation of the brain stem reticular form

ISSN:1323-1316    

DOI:10.1111/j.1440-1819.1965.tb00043.x

出版商:Blackwell Publishing Ltd    

年代:1965

数据来源: WILEY

ISSN:1323-1316    

DOI:10.1111/j.1440-1819.1965.tb00044.x

出版商:Blackwell Publishing Ltd    

年代:1965

数据来源: WILEY

ISSN:1323-1316    

DOI:10.1111/j.1440-1819.1965.tb00045.x

出版商:Blackwell Publishing Ltd    

年代:1965

数据来源: WILEY