摘要:

AbstractTwo surfactants, one containing a six and the other containing a nine unit polyoxyethylene glycol side chain attached to p‐(1,1,3,3‐tetramethylbutyl) phenol (TOPOH), were prepared with specific14C‐labeling. The radioactive label was introduced into the first ethylene oxide unit attached to the aryl moiety, TOPOCH2*CH2(OCH2CH2)nOH, by coupling chloroacetic‐14C‐l acid with TOPOH. A 4‐step reaction scheme was utilized in the synthesis, and all reactions gave excellent yields except for the final Williamson coupling reaction. A competing elimination reaction occurred in the final reaction to afford a vinylic by‐product, TOPOCHCHCl, which was identified by spectroscopic methods. The overall yields for TOP(OCH2CH2)6OH and TOP(OCH2CH2)9OH were 42 and 33 per cen

ISSN:0362-4803    

DOI:10.1002/jlcr.2580120112

出版商:John Wiley&Sons, Ltd.    

年代:1976

数据来源: WILEY

摘要:

AbstractTwo molecularly homogeneous nonionic detergents with specific‐14C labeling were prepared. Polyoxyethylene glycols of six and nine ethylene oxide units were coupled to 2,6,8‐trimethyl‐4‐nonanol (TMNOH). The radioactive label was in the first ethylene oxide unit attached to the alkyl moiety, TMNOCH2*CH2(OCH2CH2)nOH. All react ions employed in this synthesis gave good to excellent results. Two routes were developed for the reduction of an alkoxyacetic acid intermediate to the corresponding alcohol, and both methods gave excellent yields. The overall yields for TMN(OCH2CH2)6OH and TMN(OCH2CH2)9OH were 4Z and 33 per cent, respe

ISSN:0362-4803    

DOI:10.1002/jlcr.2580120113

出版商:John Wiley&Sons, Ltd.    

年代:1976

数据来源: WILEY

摘要:

AbstractRhodium‐catalyzed carbonylation of methanol at mild temperature and pressure has been developed for small‐ and large‐scale preparations of the carbon isotope isomers of acetic

ISSN:0362-4803    

DOI:10.1002/jlcr.2580120114

出版商:John Wiley&Sons, Ltd.    

年代:1976

数据来源: WILEY

摘要:

AbstractConvenient methods have been developed for the preparation of specifically tritiated arene oxides. K‐Region arene oxides of phenanthene, benzo[a]anthracene and benzo[a]pyrene were prepared from triatiated cis dihydrodiolsviathe methoxydioxolane route and the non‐K‐region arene oxides, benzo[a]pyrene 7,8‐ and 9,10‐oxide, were preparedviatriated halphydr

ISSN:0362-4803    

DOI:10.1002/jlcr.2580120115

出版商:John Wiley&Sons, Ltd.    

年代:1976

数据来源: WILEY

摘要:

AbstractLithiation of 4‐benzyloxy‐2‐bromotoluene and subsequent quenching of the lithiated product affords 4‐benzyloxytoluene‐2‐t which is oxidized directly to 4‐benzyloxybenzaldehyde‐2‐t with ceric ammonium nitrate. Transformation of the aldehyde6by standard procedures affords DL‐tyrosine‐2

ISSN:0362-4803    

DOI:10.1002/jlcr.2580120116

出版商:John Wiley&Sons, Ltd.    

年代:1976

数据来源: WILEY

摘要:

AbstractA convenient method for the synthesis of cyclopropyl cyanide‐2,2‐d2has been elaborated. Reduction of methyl 3‐cyanopropionate with lithium borodeuteride followed by reaction of the resulting alcohol with triphenylphosphine and carbon tetrachloride gave 4‐chlorobutyronitrile‐4,4‐d2. Conversion of the chloride to the iodide with sodium iodide followed by cyclization with sodium hydride afforded cyclopropyl cyanide‐2,2‐d2in 30% overall yield with deuterium incor

ISSN:0362-4803    

DOI:10.1002/jlcr.2580120117

出版商:John Wiley&Sons, Ltd.    

年代:1976

数据来源: WILEY

ISSN:0362-4803    

DOI:10.1002/jlcr.2580120118

出版商:John Wiley&Sons, Ltd.    

年代:1976

数据来源: WILEY

ISSN:0362-4803    

DOI:10.1002/jlcr.2580120119

出版商:John Wiley&Sons, Ltd.    

年代:1976

数据来源: WILEY

ISSN:0362-4803    

DOI:10.1002/jlcr.2580120101

出版商:John Wiley&Sons, Ltd.    

年代:1976

数据来源: WILEY