摘要:

AbstractPartant de Ba13CO3, K13CN ou de phtalimide, nous décrivons la synthèse et la purification d'acides gras, d'amines grasses et de N acyl amino acides marqués spécifiquement au13C ainsi que d'amines grasses marquées à l'azote 15. L'identification et la pureté de ces composés ont été effectuées par SM

ISSN:0362-4803    

DOI:10.1002/jlcr.2580190902

出版商:John Wiley&Sons, Ltd.    

年代:1982

数据来源: WILEY

摘要:

The syntheses of 2‐13C and 3‐13C indoles and indolizines and 1‐13C indolizine are described. They are obtained from 1‐13C bromoacetaldehyde on (2‐pyridyl) ethylacetate for 2‐13C indolizine, and through cyclisations of suitably labelled intermediates:o‐formotoluidide for 2‐13C indole, o,β‐dinitrostyrene for 3‐13C indole, and 3‐(2‐pyridyl)‐1 propanol for 3‐13C and for 1‐13C indolizines. Every position

ISSN:0362-4803    

DOI:10.1002/jlcr.2580190903

出版商:John Wiley&Sons, Ltd.    

年代:1982

数据来源: WILEY

ISSN:0362-4803    

DOI:10.1002/jlcr.2580190904

出版商:John Wiley&Sons, Ltd.    

年代:1982

数据来源: WILEY

摘要:

AbstractDie Synthese von14C‐Ring‐markiertem 8‐Methoxypsoralen (MELADININE) wird beschrieben. Auf die säulenchromatographische Reinigung der einzelnen Produkte sowie auf die radiodünnschichtchromatographische Reinheit und Identitätskontrolle besonders des Endproduktes wird eingegangen. Ausgehend von (2‐14C)‐Chloressigsäure und Pyrogallol werden 860 mg (4 mMol) (2′‐14C)‐8‐Methoxypsoralen mit einer spezifischen Radioaktivität von 1,3 mCi/mMol, [6,0 μCi/mg; 2,2 × 105Bq/mg] in einer 8‐Stufen‐Synthese hergestellt. Die Ausbeute, präparativ und radi

ISSN:0362-4803    

DOI:10.1002/jlcr.2580190905

出版商:John Wiley&Sons, Ltd.    

年代:1982

数据来源: WILEY

摘要:

AbstractA simple synthetic procedure has been developed for the preparation of deuterated zomepirac. The deuterium was incorporated into the aromatic ring which is a metabolically stable position.

ISSN:0362-4803    

DOI:10.1002/jlcr.2580190906

出版商:John Wiley&Sons, Ltd.    

年代:1982

数据来源: WILEY

摘要:

AbstractThis report describes the synthesis of carbon‐13 labeled n‐octyltrichloro silane from13C‐barium carbonate. The product is labeled at the 8‐position of the alky

ISSN:0362-4803    

DOI:10.1002/jlcr.2580190907

出版商:John Wiley&Sons, Ltd.    

年代:1982

数据来源: WILEY

摘要:

AbstractThe base‐catalysed exchange of a proton of the methyl groups in acetanilides can be used to incorporate deuterium into these amides. 4′‐Hydroxy‐2[2H]acetanilide (acetaminophen, paracetamol) can be prepared by the demethylation with boron tribromide of 4′‐methoxy‐2[2H]acetamide obtained by this base‐cat

ISSN:0362-4803    

DOI:10.1002/jlcr.2580190908

出版商:John Wiley&Sons, Ltd.    

年代:1982

数据来源: WILEY

摘要:

AbstractMethyl [1‐14C]docosa‐7,10,13,16‐tetraenoate was prepared from [1‐14C]arachidonic acid by two successive Arndt‐Eistert syntheses which also can be used for the step‐wise homologation of other labeled fatty acids. After purification by gas chromatography the specific activity was 6.16 mCi/mmol, and the radiochemical pur

ISSN:0362-4803    

DOI:10.1002/jlcr.2580190909

出版商:John Wiley&Sons, Ltd.    

年代:1982

数据来源: WILEY

摘要:

By the exchange of the central atom of ferrocenes with191OsCl4in the presence of HCl labelled osmocenes were gained with radiochemical yields up to 45 %. The organ‐distribution of the labelled osmocenes were compared with that of the homologous ruthenocenes and that of the OsCl4and RuCl

ISSN:0362-4803    

DOI:10.1002/jlcr.2580190910

出版商:John Wiley&Sons, Ltd.    

年代:1982

数据来源: WILEY

摘要:

Abstract2‐Naphthalene‐d7‐sulfonic acid, required as an internal standard for the analysis of organic compounds in water by gas chromatography/mass spectrometry, was synthesized in one step from commercially available naphthalene‐d8and sulfuric acid‐d2. A high‐performance liquid chromatographic method was developed to separate 1‐ and 2‐naphthalene‐d7‐sulfonic acids. The electron impact mass spectrum and isotopic purity of the 2‐naphthalene‐d7‐sulf

ISSN:0362-4803    

DOI:10.1002/jlcr.2580190911

出版商:John Wiley&Sons, Ltd.    

年代:1982

数据来源: WILEY