摘要:

Progressive hearing loss is a potential complication of Paget's disease, a metabolic disorder of accelerated bone formation and resorption. Calcitonin (Calcimar) is a recently introduced synthetic hormone used as a systemic treatment. Some studies have shown it to halt the progression of hearing loss. This is the first study of the effects of calcitonin on hearing loss to use a large number of patients with continuous use of the drug and long-term follow-up. It confirms that the drug is effective.We conducted chart reviews to compare the degree of hearing loss over time in 45 patients. Twenty-six patients have been taking salmon calcitonin for five to eight years to date and nineteen have received no treatment. Hearing loss was recorded at the initial examination (trial 1), one to four years later (trial 2), and then one to five years after the second evaluation (trial 3). Statistical analyses show a strong relationship between treatment and rate of hearing loss. The average hearing loss in the control group progressed from 47 dB in the first trial to 59 dB in the second trial to 75 dB in the third trial. Average hearing loss in the treated group remained at 47 dB over time. The difference in hearing loss over time between the two groups was less than 1 dB for the treated group and more than 28 dB for the control group.Results thus clearly show that calcitonin is effective in halting the progression of hearing loss in Paget's disease.

ISSN:0192-9763    

出版商:OVID    

年代:1986

数据来源: OVID

摘要:

A cochlear implant program was started in Jeddah, Saudi Arabia, in September 1983. Three totally deaf adult patients have received implants so far, with encouraging results. The problems of cochlear implantation in developing countries are discussed with regard to the patient, team, and device. The rationale, stages, and future of the program are outlined.

ISSN:0192-9763    

出版商:OVID    

年代:1986

数据来源: OVID

摘要:

Radical mastoidectomy has for years been the method chosen for the treatment of chronic middle ear disease. The numerous inflammatory problems linked to this cavity have been dealt with differently by various authors. We have examined the literature and refer to our own data, from a study carried out in twenty-four subjects, showing unsatisfactory results subsequent to a previous radical mastoidectomy.In ten of these subjects, middle ear cleft reconstruction was performed using a posterior canal wall prosthesis in Ceravital; in the remaining fourteen subjects complete obliteration with costal cartilage and a mixture of bone paté and fibrin glue (Tissucol) was carried out.In both groups the reconstruction of the conductive system was carried out by the insertion of total or partial ossicular replacement prostheses in Plastipore. The comparison of findings in the two groups revealed slightly better functional results in all two-stage procedures and in reconstructions performed with Ceravital. However, the one-stage procedure proved to be equally effective in resolving the inflammatory problems.

ISSN:0192-9763    

出版商:OVID    

年代:1986

数据来源: OVID

摘要:

This report focuses on auditory brain stem response (ABR) from the ear contralateral to large cerebellopontine angle (CPA) tumors. Specifically, eleven of fifteen patients with large CPA tumors demonstrated contralateral ABRs for which wave IV and/or V were abnormal, while waves I and III were normal. In some cases, waves IV and/or V were absent, while in other cases one or both waves were delayed. The clinical interpretation for this type of ABR finding and the possible implications in relation to generator sites of the various ABR waves are discussed.

ISSN:0192-9763    

出版商:OVID    

年代:1986

数据来源: OVID

摘要:

We report the case of a profoundly deaf 4-year-old boy with congenital deafness as a result of Mondini's dysplasia. The Mondini inner ear malformation is the result of arrested labyrinthine development during embryogenesis and is characterized by both bony and membranous anomalies of the inner ear. The dysplastic cochlear anatomy does not preclude successful cochlear implantation, and electrical threshold measurements are similar to those recorded in pediatric subjects deafened as a result of other causes.

ISSN:0192-9763    

出版商:OVID    

年代:1986

数据来源: OVID

摘要:

Magnetic resonance (MR) has been employed for the study of patients with peripheral and retrolabyrinthine otologic pathology. Its usefulness has been compared with that of computed tomography (CT). CT remains at present the best study for the assessment of patients with conductive hearing loss and sensorineural hearing loss or vestibular disorders of the peripheral type. However, MR is the study of choice of retrolabyrinthine pathology occurring in the internal auditory canals, cerebellopontine cisterns, and brainstem.

ISSN:0192-9763    

出版商:OVID    

年代:1986

数据来源: OVID

摘要:

Two hundred and two operations on patients with a congenital ear malformation are presented. Special emphasis is placed on those patients seen in the past three years. The goal of surgery is normal, or near normal, hearing in the operated ear. The surgical approach is direct to the middle ear, and the mastoid air cell system is not opened. Temporalis fascia is used for the new tympanic membrane and a center hole split-thickness skin graft is used to line the new ear canal. In the uncomplicated atresia patient, the postoperative speech reception threshold is routinely 15 to 25 dB.

ISSN:0192-9763    

出版商:OVID    

年代:1986

数据来源: OVID

摘要:

ABSTRACTAn erosive mucosal cyst of the mastoid process is reported. The endodermal lining contained both goblet and nonkeratinizing squamous metaplastic mucosa. Possible causes of cyst formation and its relationship to epidermoid and “motor oil” cysts are discussed.

ISSN:0192-9763    

出版商:OVID    

年代:1986

数据来源: OVID

摘要:

A case of progressive facial weakness associated with an anomaly of the internal auditory canal and labyrinthine segment of the facial nerve is documented with clinical, radiological, and surgical findings. Each portion of a double internal auditory canal (aberrant facial nerve canal) was found to contain a portion of the facial nerve, and each portion of the facial nerve was explored because a tumor was suspected to be the cause of the progressive weakness. However, no mass was found. The embryologic factors that may lead to such an abnormality and the pathophysiologic mechanisms that may have resulted in the facial weakness are discussed.

ISSN:0192-9763    

出版商:OVID    

年代:1986

数据来源: OVID

ISSN:0192-9763    

出版商:OVID    

年代:1986

数据来源: OVID