摘要:

The physical work capacity of a population of older men and women living in rural municipalities of Eastern Ontario, Canada, was similar to the one observed on a group of Swedes living in the urban district of Uppsala. The physical work capacity test determined at 150 heart frequency per minute (PWC-150) in older men and women did not appear to be heart rate/age-related. There appeared to be no relationship between physical stature and heart rate response to physical exercise in the men and women tested.

ISSN:0304-324X    

DOI:10.1159/000212993

出版商:S. Karger AG    

年代:1989

数据来源: Karger

摘要:

Venous plasma noradrenaline (NA) kinetics, determined using steady-state intravenous infusions of subpressor doses of [3H] NA, were measured in 8 young, 13 middle-aged and 8 elderly subjects. Plasma NA concentrations were 0.71 nmol/l (0.25–0.98) in the young, 1.90 nmol/l (0.98–3.65) in the middle-aged and 3.03 nmol/l (1.15–3.85) in the elderly (young vs. elderly, p < 0.001). NA spillover rates were 2.07 nmol/l/m2 (1.05–4.91) in the young, 3.91 nmol/l/m2 (1.62–9.44) in the middle-aged and 7.57 nmol/l/m2 (4.38–24.0) in the elderly (young vs. elderly, p < 0.001). Plasma NA clearance was similar in young and elderly subjects. NA spillover was positively correlated with age (r = 0.58; p < 0.01) and was not independently related to blood pressure. The rise in plasma NA with age results from an increase in spillover rate rather than any alteration i

ISSN:0304-324X    

DOI:10.1159/000212994

出版商:S. Karger AG    

年代:1989

数据来源: Karger

摘要:

Addition of an antioxidant, sodium hypophosphite (SHP; 1 mM), to the diet of Zaprionus paravittiger (Diptera) results in depressed ATPase activity in both the sexes in comparison to the normal group. However, the rate of age-related decline in ATPase activity is lowered considerably in SHP fed group. Such changes in ATPase activity might be one of the important factors responsible for increased life span of flies with SHP feeding.

ISSN:0304-324X    

DOI:10.1159/000212995

出版商:S. Karger AG    

年代:1989

数据来源: Karger

摘要:

Alterations with aging in the responses of heart rate (HR) and blood pressure (BP) reactivity were investigated during mild mental stress induced by undergoing a psychometric test, in 52 women and men aged 18–73 years, with no history of cardiovascular, renal or neurological deficits. HR and BP responses were measured before, during and after the test. Resting HR and diastolic BP (DBP) were not age-related while resting systolic BP (SBP) was. HR and SBP were increased during test performance. HR reactivity, measured during task execution as well as during recovery, was significantly decreased in older subjects. DBP recovery variation was lowered with age. These results indicate that age is an important determinant of the magnitude of cardiovascular adjustment during minor mental stress in women and me

ISSN:0304-324X    

DOI:10.1159/000212996

出版商:S. Karger AG    

年代:1989

数据来源: Karger

摘要:

The identification of the rheological variables responsible for alterations in capillary blood flow caused by the aging process could help explain why the incidence of vascular disease increases with age. Using new techniques for the separation and micropore filtration of the haemocellular subpopulations in 110 subjects aged 21–84 years, the aim of this study was to show to what extent, if any, age influences blood cell deformability. The filterability of mononuclear leucocytes decreased with age (r = 0.25; p < 0.001), whereas the filterability of polymorphonuclear leucocytes or erythrocytes did not change significantly with ag

ISSN:0304-324X    

DOI:10.1159/000212997

出版商:S. Karger AG    

年代:1989

数据来源: Karger

摘要:

A rereading of The Rate of Living [Pearl, University of London Press, London 1928] shows that Pearl’s thoughts about the meaning of inheritance and heredity, about the relations of between and within populations measurements and about the ways in which life span should be measured are unclear. New ways in which the theory should, eventually, be tested are suggested and the genetic implications of these suggested experimental ways are given. A review is made, mainly in insects, accessorily in rodents, of the different manners in which the theory has been essayed, namely by relating life span with temperature, rate of energy expenditure, growth rate and activity. It is concluded that the theory rests on a weak theoretical basis and even on a series of highly nonplausible assumptions and that, furthermore, the evidence experimentally accumulated is, with a few odd exceptions, not in favor of the theor

ISSN:0304-324X    

DOI:10.1159/000212998

出版商:S. Karger AG    

年代:1989

数据来源: Karger

ISSN:0304-324X    

DOI:10.1159/000212999

出版商:S. Karger AG    

年代:1989

数据来源: Karger