ISSN:0023-852X    

DOI:10.1288/00005537-198503000-00001

出版商:John Wiley&Sons, Inc.    

年代:1985

数据来源: WILEY

ISSN:0023-852X    

DOI:10.1288/00005537-198503000-00002

出版商:John Wiley&Sons, Inc.    

年代:1985

数据来源: WILEY

摘要:

AbstractDuring the past 15 years a series of 25 middle ear implants was removed at the time of revision surgery and prepared for histological study. These revision operations were performed because of failure to control the disease and/or persistent or recurring hearing loss. The ossicular and cortical bone autografts showed similar behavior in that they underwent creeping substitution with vitalized bone in amounts varying from 0% to 83%. There was no correlation to duration of implantation. The four cartilage grafts, on macroscopic evaluation, showed a loss of rigidity. Two of three cartilage autografts showed a high rate of survival of chondrocytes. The two TORP prostheses showed extensive invasion of their porous spaces with foreign body giant cells. One of the latter, implanted for over four years showed fibrous replacement of plastic material. The two polyethylene tubes showed intraluminal foreign body reaction and new bone formation.

ISSN:0023-852X    

DOI:10.1288/00005537-198503000-00003

出版商:John Wiley&Sons, Inc.    

年代:1985

数据来源: WILEY

摘要:

AbstractThe immunologic explosion has now reached the field of otology. By having better techniques to measure the changes at cellular and molecular levels, it is now possible to devise experiments to show morphologic anatomic changes as well as functional changes.The demonstration in 1980 (M.S.) that tympanosclerosis could be induced immunologically represents a concrete advancement in immunologic thinking in conceptualization of otologic disease.In 1974, one of the authors (M.S.) published work dealing with the treatment of vasculitis of immunologic origin for sudden hearing loss. This was aimed at inhibiting the complement cascade from starting its destructive action. Recently, the immunologic challenge in animals demonstrated by changes in the inner ear was shown by one of the authors (T.J.Y.). Such changes were compatible with labyrinthine hydrops, or Meniere's disease, otosclerosis, and sensorineural hearing loss and vestibular dysfunction.

ISSN:0023-852X    

DOI:10.1288/00005537-198503000-00004

出版商:John Wiley&Sons, Inc.    

年代:1985

数据来源: WILEY

摘要:

AbstractAural cholestentomas may arise in the middle ear by a variety of mechanisms; in some cases it appears that cholesteatomas arise within or behind an intact tympanic membrane. We have observed that microcholesteatomas arise within the tympanic membrane of mongolian gerbils which have keratin accumulations on the lateral surface of the tympanic membrane. An ultrastructural study of the keratinizing epithelium of these animals showed that breaks in the basal lamina allow pseudopods of epithelial cells to extend into the lamina propria and form epithelial cones. The basal lamina later reconstituted itself. Keratinization may occur within these ingrowing cones forming microcholesteatomas. This sequence of events may explain the occurrence of intratympanic cholesteatomas in humans in the absence of invagination or perforation.

ISSN:0023-852X    

DOI:10.1288/00005537-198503000-00005

出版商:John Wiley&Sons, Inc.    

年代:1985

数据来源: WILEY

摘要:

AbstractBooks and monographs received are acknowledged in this column. This notice may be regarded as a return courtesy to the publisher or author. Reviews will be published later as the editor may elect.Notice of each book or monograph, including title, name of author, publisher, pagination, price, etc., will be presented in these notices so that our readers may have all data at their disposal for further inquiry.

ISSN:0023-852X    

DOI:10.1288/00005537-198503000-00006

出版商:John Wiley&Sons, Inc.    

年代:1985

数据来源: WILEY

摘要:

AbstractAn analysis is made of 134 patients with nasopharyngeal carcinoma treated from 1971‐1980 at the Cancer Control Agency of British Columbia.Incidence rate for Chinese born in the Orient was 20.5 per 100,000 per year compared to 1.32 per 100,000 for Canadian born Chinese. The Caucasian rate was .19 per 100,000 per year. These figures confirm a 15 times greater incidence of the disease in Chinese born in the Orient over those born in North America.The 86 Chinese patients were noted to have a 10% poorer survival than the 48 Caucasian patients on long‐term follow‐up.The main factor affecting survival was initial staging. Overall survival rates were 46.3% three year, no evidence of disease (NED) and 38.3% five year NED survival, but when disease was limited to the nasopharynx (T1, T2, N0) they were 73.9% three year NED and 66.6% five year NED survival.One‐third of the patients ultimately developed distant metastases below the clavicle. Although lower T and N stage cases had fewer of these, the overall correlation with staging was poor.Female patients showed statistically significant better survival which was not related to better initial staging. They did, however, have 11% fewer eventual distant met

ISSN:0023-852X    

DOI:10.1288/00005537-198503000-00007

出版商:John Wiley&Sons, Inc.    

年代:1985

数据来源: WILEY

摘要:

AbstractGlomus jugulure tumors are rather common in the middle ear and temporal bone. They are usually easy to diagnose and surgically remove.However, there are a comparatively large number of these growths which not only cause extensive local destruction, but can spread distally and even have endocrine manifestations. This group is difficult to diagnose and manage despite recent advances in diagnostic procedures and the advent of skull base surgery. There is a void in the literature of a large series of cases being followed for a long period of time.This paper presents a comprehensive detailed statistical ten‐year follow‐up of 231 glomus jugulare tumors. The results suggest that our present diagnostic procedures often are inadequate in finding small tumors, and our treatment and follow‐up are lacking because these tumors tend to recur often at a late date and in a different form.A comprehensive method of approach of diagnosis and treatment is described to manage all cases of glomus jug

ISSN:0023-852X    

DOI:10.1288/00005537-198503000-00008

出版商:John Wiley&Sons, Inc.    

年代:1985

数据来源: WILEY

摘要:

AbstractAcute epiglottitis may be fatal when diagnosis is delayed. The literature stresses data that does not help to predict impending airway obstruction in patients who present with a sore throat, the most consistent presenting symptom among patients with acute epiglottitis. In this review of 80 cases of epiglottitis in adults, almost all patients who presented within eight hours from onset of symptoms required airway intervention, while the majority of those who presented more than eight hours after onset of symptoms never developed acute upper respiratory obstruction and were treated medically or had supportive treatment only. Artificial airway was indicated in all patients who had drooling. There were no fatalities in this series, however, we recommend keeping all patients with acute epiglottitis in an intensive care unit for at least 24 hours after admission.

ISSN:0023-852X    

DOI:10.1288/00005537-198503000-00009

出版商:John Wiley&Sons, Inc.    

年代:1985

数据来源: WILEY

摘要:

AbstractAt least three clinical variations of idiopathic ulceration of the oropharyngeal cavity are recognized. Major (or giant) aphthous ulceration is uncommon but may affect the hypopharynx producing severe pain, dysphagia, and severe scarring. Healing with systemic prednisolone may require large and prolonged dosage. In 7 out of 14 patients with hypopharyngeal ulceration gastrostomy was performed to assist nutrition and by‐pass the cricopharyngeal region in an attempt at reducing subsequent scarrin

ISSN:0023-852X    

DOI:10.1288/00005537-198503000-00010

出版商:John Wiley&Sons, Inc.    

年代:1985

数据来源: WILEY