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1. |
Title Page |
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Nephron,
Volume 33,
Issue 2,
1983,
Page 73-74
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ISSN:1660-8151
DOI:10.1159/000182914
出版商:S. Karger AG
年代:1983
数据来源: Karger
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2. |
Table of Contents |
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Nephron,
Volume 33,
Issue 2,
1983,
Page 75-75
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PDF (117KB)
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ISSN:1660-8151
DOI:10.1159/000182915
出版商:S. Karger AG
年代:1983
数据来源: Karger
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3. |
Dedication to Belding H. Scribner |
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Nephron,
Volume 33,
Issue 2,
1983,
Page 77-78
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PDF (340KB)
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ISSN:1660-8151
DOI:10.1159/000182916
出版商:S. Karger AG
年代:1983
数据来源: Karger
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4. |
Blind Hemodialysis: An Important Research Tool |
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Nephron,
Volume 33,
Issue 2,
1983,
Page 79-82
Suhail Ahmad,
Rex Gentry,
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摘要:
Results of clinical research which require subjective data collection can be influenced by expectations of patients and staff; thus, treatment variables should be easily, safely and effectively concealed. We describe a unique dialysis setup which enables us to conduct double- and single-blind variations in dialysis technique. Six studies involving over 4,700 dialyses are discussed to emphasize the significance of this approach to research.
ISSN:1660-8151
DOI:10.1159/000182917
出版商:S. Karger AG
年代:1983
数据来源: Karger
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5. |
Monoclonal Antibodies to Human Glomerular Cells: A Marker for Glomerular Epithelial Cells |
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Nephron,
Volume 33,
Issue 2,
1983,
Page 83-90
Wayne W. Hancock,
Robert C. Atkins,
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摘要:
A monoclonal antibody, PHM 5, directed against human glomerular epithelial cells, was prepared after immunisation of a mouse with isolated human glomeruli and fusion of spleen cells with a mouse myeloma. Binding of antibody to isolated glomeruli was detected by radioimmune indirect binding assay, and specificity for glomerular epithelial cells was shown using a four-layer peroxidase-antiperoxidase technique applied to epoxy resin sections of the human kidney cortex. PHM 5 appears to detect a human-specific cell surface carbohydrate antigen not previously described, and can be used to identify epithelial cells in renal biopsy sections and in culture outgrowths of isolated glomeruli.
ISSN:1660-8151
DOI:10.1159/000182918
出版商:S. Karger AG
年代:1983
数据来源: Karger
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6. |
Cardiac Arrhythmias in Patients on Maintenance Hemodialysis |
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Nephron,
Volume 33,
Issue 2,
1983,
Page 91-95
A. Blumberg,
M. Häusermann,
B. Strub,
H.R. Jenzer,
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摘要:
17 patients on maintenance hemodialysis were monitored for cardiac arrhythmias using ambulatory electrocardiographic recording. Atrioventricular dissociation was found in a patient with an elevated serum digoxin concentration, intradialytic supraventricular tachycardia had been present in a second patient during acute uremic pericarditis prior to the study. Ventricular premature beats (VPB) were absent or of low grade (occasional/uniform) in 14 patients and did not increase on dialysis. 3 patients had potentially dangerous VPB of higher grades (multiform, salvos or R on T) which occurred on or after dialysis in 2. 2 of these 3 patients were overdigitalized, and 2 had severe cardiac disease (amyloid, old myocardial infarction). Several other risk factors (age, hypertension, cardiac hypertrophy, smoking, hyperlipidemia, electrolyte changes) did not seem to be of importance for VPB. In these patients on maintenance hemodialysis, potentially dangerous VPB were rare and occurred mainly during or after dialysis in patients with preexisting heart disease and/or digitalization.
ISSN:1660-8151
DOI:10.1159/000182919
出版商:S. Karger AG
年代:1983
数据来源: Karger
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7. |
Control of Hypertension and Prolonged Survival on Maintenance Hemodialysis |
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Nephron,
Volume 33,
Issue 2,
1983,
Page 96-99
Bernard Charra,
Edouard Calemard,
Marc Cuche,
Guy Laurent,
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摘要:
52 patients started dialysis in our center prior to 1971. When this study ended in December 1980, 8 patients had been lost to follow-up, and 7 had died, none of stroke or myocardial infarction. The overall actuarial survival rate was 85% at 10 years. For all patients treatment consisted of a long (24–30 h/week) slow hemodialysis on standard Kiil dialysers throughout the 10 years. Good blood pressure (BP) control was achieved by a strict maintenance of dry weight alone (low salt diet, but no antihypertensive drug), even in 12 patients dialyzing only twice a week. This population remained completely free of both myocardial infarctions and cerebrovascular accidents. This experience suggests that if BP is well controlled, accelerated atherosclerosis is not the inevitable complication of long-term hemodialysis. The authors believe that the long, slow dialysis technique they use is the key to the good BP control achieved uniformly in this serie
ISSN:1660-8151
DOI:10.1159/000182920
出版商:S. Karger AG
年代:1983
数据来源: Karger
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8. |
Parathyroidectomy in Chronic Renal Failure |
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Nephron,
Volume 33,
Issue 2,
1983,
Page 100-105
J.K. Dawborn,
D.J. Brown,
M.C. Douglas,
H.H. Eddey,
W.F. Heale,
D.P. Thomas,
J.M. Xipell,
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摘要:
Parathyroidectomy was carried out in 26 patients over a 14-yεar period. Excellent results were obtained in patients with severe hyperparathyroidism. Vascular calcification, hypercalcaemia and pruritus did not justify surgery unless associated with unequivocal hyperparathyroidism. 13 patients required intravenous calcium infusion for up to 2 weeks to control post-operative hypocalcaemia. Calcium requirements could be predicted from the pre-operative plasma alkaline phosphatase level. Following operation continued treatment with vitamin D was necessary to prevent hypocalcaemia. Hyperparathyroidism recurred in 1 patient after 8 years and 4 patients developed osteomalacia. Since parathyroid hormone may have toxic effects other than those on bone, maintenance of normal levels should be a long-term objective in the treatment of patients with chronic renal failure. Where large parathyroid glands are present, surgical reduction in gland mass is a logical prelude to long-term suppression of parathyroid hormone with vitamin D and phosphate-binding agents.
ISSN:1660-8151
DOI:10.1159/000182921
出版商:S. Karger AG
年代:1983
数据来源: Karger
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9. |
A Hemodialysis Orientation Unit |
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Nephron,
Volume 33,
Issue 2,
1983,
Page 106-110
Joseph W. Eschbach,
Maureen Seymour,
Ann Potts,
Marcia Clark,
Christopher R. Blagg,
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摘要:
A separate dialysis unit was created within an existing large dialysis unit for the purpose of segregating all new hemodialysis patients into an environment that would provide optimum instruction about self-care. An educational curriculum was presented to each patient during each dialysis over the first 2 months of dialysis. Depending upon medical condition and response to the curriculum, patients were transferred either to the home hemodialysis training unit with or without a helper, to the limited care facility, or to the general dialysis area for medically unstable patients. An orientation unit not only improves patient participation in self-care, but appears to increase the number of patients interested in dialyzing at home.
ISSN:1660-8151
DOI:10.1159/000182922
出版商:S. Karger AG
年代:1983
数据来源: Karger
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10. |
Characteristics of Long-Term (14 Years) Survivors of Maintenance Dialysis |
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Nephron,
Volume 33,
Issue 2,
1983,
Page 111-115
Robert A. Gutman,
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摘要:
The characteristics of 25 men and women who have been maintenance dialysis patients for at least 14 years (average 15.7 years) were tabulated on the basis of a survey instrument. In addition to repeated problems with vascular access surgery, the most common medical problems surround difficulties with musculoskeletal system. The most severe manifestation of this was a fibrosing arthropathy and repeated pathologic fractures. Cardiovascular morbidity was less prominent. As a group, these patients were characterized largely as ‘independent, organized and cheerful’. The average calculated dose of dialysis for this group was 27 m2 · h/70 kg body weight per
ISSN:1660-8151
DOI:10.1159/000182923
出版商:S. Karger AG
年代:1983
数据来源: Karger
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