摘要:

Disturbances in testicular function develop in uraemic patients, but the effect of haemodialysis on them has not been determined definitively. Because of this, 22 patients with chronic renal failure who were receiving regular dialysis treatment underwent studies of the hypothalamo-pituitary-testicular axis before, during and after a dialysis. On all these occasions, serum testosterone concentrations were lower than the values found in 26 normal men. In contrast, serum concentrations of FSH and LH were higher than normal. 13 of these patients showed a normal response of the hypothalamo-pituitary system to the clomiphene stimulation test and a diminished response of Leydig’s cells to the human chorionic gonadotropin stimulation test. It is concluded that haemodialysis does not affect the impaired gonadal function of male uraemic patient

ISSN:1660-8151    

DOI:10.1159/000182066

出版商:S. Karger AG    

年代:1981

数据来源: Karger

摘要:

We analyzed 50 consecutive cadaver renal transplants to ascertain what benefit, if any, accrued from pre-transplantation splenectomy. Because antithymocyte globulin was administered in a random fashion to some patients, its effects were also analyzed. Recipient modification with either modality enhanced graft survival in first transplants when compared to no modification (splenectomy versus no modification 62 versus 27%, p = 0.06; ATG versus modification 75 versus 27%, p = 0.01). The collective experience with splenectomy, its rationale, and its complications are discussed.

ISSN:1660-8151    

DOI:10.1159/000182067

出版商:S. Karger AG    

年代:1981

数据来源: Karger

摘要:

Glucose intolerance in uremia has been recognized for over 70 years. While its importance is unclear, study of this phenomenon has led to wider understanding of the complicated pathophysiology of renal failure.

ISSN:1660-8151    

DOI:10.1159/000182068

出版商:S. Karger AG    

年代:1981

数据来源: Karger

ISSN:1660-8151    

DOI:10.1159/000182069

出版商:S. Karger AG    

年代:1981

数据来源: Karger