ISSN:1660-8151    

DOI:10.1159/000183919

出版商:S. Karger AG    

年代:1986

数据来源: Karger

摘要:

Digital intravenous angiography is a simple and safe procedure and can be performed on an outpatient basis. Poor function of a hemodialysis vascular access due to increased graft resistance, reduced arterial inflow or shunt steal can be evaluated by this technique. Complications of direct graft puncture or conventional arteriography can be avoided using digital angiography.

ISSN:1660-8151    

DOI:10.1159/000183920

出版商:S. Karger AG    

年代:1986

数据来源: Karger

摘要:

The platelet aggregation – enhancing action of heparin with adenosine diphosphate and epinephrine was tested in vitro in a group of volunteers. This action of heparin can be eliminated by protamine sulphate which has no effect on platelet aggregation. In dialyzed patients the aggregation effect of heparin manifested itself after haemodialysis and could also be abolished by protamine sulphate. We therefore assumed that the heparin used during dialysis was one of the factors accounting for the increased platelet aggregation after dialysi

ISSN:1660-8151    

DOI:10.1159/000183921

出版商:S. Karger AG    

年代:1986

数据来源: Karger

摘要:

Inorganic sulfate concentrations are markedly elevated in patients with chronic renal failure (CRF). During hemodialysis, sulfate is removed and circulating levels drop significantly, while chloride concentrations remain relatively constant. We measured sulfate and chloride in sweat from CRF patients collected by pilocarpine iontophoresis. Sweat sulfate concentrations in uremic patients were significantly increased (404 ± 43 vs. 105 ± 6 μM in 22 controls). The correlation between plasma and sweat SO4 concentrations in CRF patients was significant (r = 0.77, P < 0.01). However, the fractional excretion of sulfate in sweat (the sweat/serum ratio) was close to that of chloride (0.26 ± 0.01 vs. 0.19 ± 0.02) and was essentially the same before and after dialysis (0.20 ± 0.01 vs. 0.23 + 0.01) despite the significant absolute change in the extracellular SO4 concentration (from 2,018 ± 153 to 709 ± 21 μM) and no change in chloride concentrations. In patients with CRF, we conclude that the handling of inorganic sulfate by the sweat gland is not significantly different from that for chloride. Hemodialysis reduces absolute sulfate excretion markedly and thus may reduce the likehood of forming calcium sulfate complexes in the sweat secretions. This could be a significant factor in the dialysis-related pruritus that has been ascribed to excess calcium deposition in

ISSN:1660-8151    

DOI:10.1159/000183973

出版商:S. Karger AG    

年代:1986

数据来源: Karger

摘要:

The outcome and complications which developed in 8 hemodialysis patients who received 12 DiaTAP bioCarbon button vascular-access devices were reviewed. All patients had a poor vascular access history. Three of twelve devices have been replaced because of thrombosis and two because of infection. Four patients have had 10 episodes of reduced blood flow. Streptokinase infusion into the DiaTAP button led to improved blood flow in 8 of 10 episodes. The 6-month survival rate of the DiaTAP access device was 67% and the average functioning life was 9.4 months. It was a valuable form of access when others had failed.

ISSN:1660-8151    

DOI:10.1159/000183974

出版商:S. Karger AG    

年代:1986

数据来源: Karger

摘要:

Alport’s syndrome probably is a molecular disorder of basement membrane composition. Investigation of urine on basement membrane components such as hydroxylysine and its glycosides, glucosylgalactosylhydroxylysine and galactosylhydroxylysine, may be helpful for diagnosis of the disease. Urinary specimens of 33 patients and 12 siblings were investigated, and the results were compared with those of 14 healthy adults and of 29 healthy children. The urine of patients with glomerulopathies, occurring during childhood (IgA nephropathy, benign recurrent hematuria, poststreptococcal glomerulonephritis, Henoch-Schönlein nephropathy, membranoproliferative glomerulonephritis, and nephrotic syndrome due to minimal lesions), was also investigated. No marked differences between normal and diseased subjects could be demonstrated, with respect to excretion of hydroxylysine and its glycosides, in contrast to data reported in the literatu

ISSN:1660-8151    

DOI:10.1159/000183975

出版商:S. Karger AG    

年代:1986

数据来源: Karger

摘要:

A digoxin-like immunoreactive substance (DLIS) has been described in the sera of patients with renal impairment. To further investigate this problem, we measured digoxin in 50 patients with elevated serum creatinine using 4 commercial digoxin immunoassay kits (3 radioimunoassay methods and 1 fluorescence polarization immunoassay technique). Ten of the patients were receiving digoxin therapeutically, while the remainder were not receiving the drug. Two of the radioimmunoassay kits detected low amounts of DLIS in 23% of the subjects not receiving digoxin, the highest level being 0.5 nmol/l. No DLIS was detected by the other radioimmunoassay kit or by the fluorescence polarization technique. The majority of renal patients receiving digoxin had similar results by all 4 methods, although 2 patients differed by 0.6 nmol/l as measured by 2 of the radioimmunoassay kits. We conclude that the extent of interference by DLIS in digoxin immunoassays in patients with renal impairment is not as great as has been previously reported.

ISSN:1660-8151    

DOI:10.1159/000183976

出版商:S. Karger AG    

年代:1986

数据来源: Karger

摘要:

We analyzed long-term, 2- to 9-year results and risk factors in 13 patients treated with dialysis and transplantation for hypernephroma. Eight were dialyzed only, 6 died, 4 of them from metastatic disease that occurred in less than 8 months in 3. Five patients were also transplanted. Three died, 1 of metastatic disease. Two are alive, 1 with metastatic disease, 6 years after transplant, 3 years after diagnosis of metastasis. There were no differences in age and sex in those with early metastatic disease when compared to those without, but stage III-IV disease and time of less than 5 years between first and second nephrectomy were more common in those with early metastatic disease. These data indicate that a 7-month waiting time on dialysis is enough to avoid transplanting those with early recurrence, and that patients with stage III-IV and early reappearance of tumor in the second kidney are best treated with conservative management rather than a second total nephrectomy.

ISSN:1660-8151    

DOI:10.1159/000183977

出版商:S. Karger AG    

年代:1986

数据来源: Karger

摘要:

Clinico-histological features in 32 patients with nephrotic syndrome (NS) due to focal segmental glomerulosclerosis (FSGS) were examined. Thirteen (group A1 were diagnosed as cases of FSGS within 2 years of the onset of NS, and 8 (61%) showed progressive renal dysfunction. Ten (group A2) developed FSGS more than 2 years after the onset of NS and had a favorable prognosis. Nine (group B) differed from groups A1and A2 in that the remaining nonsclerosed glomeruli showed slight mesangial proliferation. All but 1 patient of group B developed FSGS within 2 years of the onset of NS, and the prognosis was poor. No patient studied showed a transition between groups A and B. In some patients, lipoid nephrosis preceded FSGS, in group A2. Thus, for an accurate prediction of the prognosis, FSGS should be divided into three subclasses, based on clinico-histological features.

ISSN:1660-8151    

DOI:10.1159/000183978

出版商:S. Karger AG    

年代:1986

数据来源: Karger

摘要:

In a comparative study of prevalence of asymptomatic bacteriuria in a Thai population, 1.4% of 955 apparently healthy adults (12 female and 1 male) were found to have positive urine culture. Of these, 6 individuals grew staphylococcal coagulase-negative, 3 grew E. coli, and the rest grew various other organisms. Among 176 patients with glomeruionephropathies (GNP), 20.5% (17 male and 16 female) yielded positive urine cultures. These included 18 positive for E. coli, 3 for staphylococcal coagulase-negative, 5 for Klebsiella and 3 for Enterobacter; the rest grew various other organisms. There was a higher overall prevalence of asymptomatic bacteriuria in GNP when compared to the controls. Heavy proteinuria is also a predisposing factor for an increase in the prevalence of asymptomatic bacteriuria in female GNP only.

ISSN:1660-8151    

DOI:10.1159/000184215

出版商:S. Karger AG    

年代:1986

数据来源: Karger