ISSN:1660-8151    

DOI:10.1159/000180848

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

31 patients with a urinary infection were treated with a single oral dose (3 g for adults and 100 mg/kg for children) of amoxycillin; 23 (74%) were cured. 20 women and 26 children were then randomly allocated to either a single dose of amoxycillin or a 5- to 7-day conventional course of the same antibiotic. The results of both treatment regimens were comparable. Single-dose therapy for the treatment of urinary-tract infections was simple, effective and well tolerated. Patients preferred taking their treatment in this manner. Failure of single-dose therapy to eradicate bacteriuria may indicate which patients require subsequent investigations of their urinary tract.

ISSN:1660-8151    

DOI:10.1159/000180849

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

16 patients with membranoproliferative glomerulonephritis had a mean serum chloride level significantly higher than that in normal subjects or in comparable groups of patients with nephrotic syndrome secondary to either systemic lupus erythematosus or to other primary nephrotic glomerular diseases. Differences in the severity of histologic alterations of the renal interstitium did not correlate with the different levels of serum chloride seen in these groups. The increased chloride concentration may be partially explained as a compensating reaction for a decrease in protein anions. However, a renal tubular acidifying defect demonstrated in one of our patients may also contribute to the hyperchloremia in some cases.

ISSN:1660-8151    

DOI:10.1159/000180850

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

Renal blood flow (RBF), outer cortioal blood flow (OC-rbf) and inner cortical blood flow were determined by the microsphere method in water-drinking rats and chronic saline-drinking rats at 3, 12 and 24 h after injection of HgCl2 4.7 mg/kg body weight. RBF and OC-rbf were decreased in both groups at 3 h post HgCl2 injection. Persistent reduction of OC-rbf was noted in water-drinking rats at 12 and 24 h post HgCl2 even though the total RBF returned to normal by 24 h. These parameters were normal in chronic saline-drinking rats. Despite normal RBF in water-drinking and saline-drinking rats, serum creatinines were still significantly elevated 24 h post HgCl2. Therefore, alterations in total renal perfusion do not entirely account for the decreased renal function that occurs under these circumstances.

ISSN:1660-8151    

DOI:10.1159/000180851

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

Exaggerated natriuresis in response to hypertonic saline infusion occurs with great regularity in patients with documented previous attacks of poststreptococcal glomerulonephritis. Five patients were studied before and after 1 week of dietary sodium restriction in order to examine the possibility that increased extracellular fluid volume might play a role in the response to acute saline infusion. Plasma renin activity (PRA) and PRA responsiveness to sodium depletion were normal, suggesting that extracellular fluid volume was not increased. In all patients, extracellular fluid volume decreased during sodium restriction, as judged by weight loss, cumulative negative sodium balance, small decreases in measured plasma volume, and appropriate increases of PRA and plasma aldosterone concentration. Hypertonic saline infusion provoked exaggerated natriuresis in all patients equally as well after dietary sodium restriction as before. Exaggerated natriuresis in poststreptococcal glomerulonephritis occurs without evidence of chronic expansion of extracellular fluid volume and is not affected by reduction of extracellular fluid volume.

ISSN:1660-8151    

DOI:10.1159/000180852

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

The long-term efficiency of chronic peritoneal dialysis was investigated during a 10-months follow-up period in eight patients with indwelling Tenckhoff catheters by determining sequential urea, creatinine and glucose clearances. Dialysis was performed in the hospital with nurses changing commercially prepared 2-liter dialysate bottles. Mean ± SE urea clearance declined from an initial value of 23.6 ± 1.5 ml/min to 17.7 ± 1.2 at the termination of the study. The mean glucose and creatinine clearance also decreased from 14.1 ± 0.9 to 10.2 ± 0.7 and from 17.5 ± 1.9 to 12.9 ± 1.0, respectively. All of these decreases were statistically significant (p < 0.05) by paired t testing analysis. It is concluded that the efficiency of chronic peritoneal dialysis may decline during maintenance therapy and that sequential clearance measurements should be obtained in all chronic peritoneal dialysis pa

ISSN:1660-8151    

DOI:10.1159/000180853

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

In order to determine the effect of dialysis on hearing acuity, 20 patients on chronic maintenance hemodialysis or peritoneal dialysis were followed with hearing examinations every 6 months over a follow-up period of 1–4 years. While 70% of the study group had some measurable hearing loss at the beginning of the study, 75% of the patients showed no deterioration of hearing loss during the follow-up period. It is suggested that hearing deficits in chronic renal failure are common and multifactorial in etiology, and that most patients undergoing chronic dialysis show no further deterioration in hearing acuit

ISSN:1660-8151    

DOI:10.1159/000180854

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

Subdural hematoma has a higher mortality rate with hemodialysis patients than the normal population. One reason for this is the coagulation abnormalities of hemodialyzed patients. One case of a successfully treated subdural hematoma in a chronic peritoneal dialysis patient is presented. Changing the mode of dialysis from hemodialysis to peritoneal dialysis in a patient suspected of having a subdural hematoma may be beneficial in improving overall survival.

ISSN:1660-8151    

DOI:10.1159/000180855

出版商:S. Karger AG    

年代:1977

数据来源: Karger

ISSN:1660-8151    

DOI:10.1159/000180856

出版商:S. Karger AG    

年代:1977

数据来源: Karger

ISSN:1660-8151    

DOI:10.1159/000180857

出版商:S. Karger AG    

年代:1977

数据来源: Karger