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1. |
Hemodialysis versus the Newer Techniques |
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Nephron,
Volume 27,
Issue 1,
1981,
Page 1-1
G.M. Berlyne,
S. Giovannetti,
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ISSN:1660-8151
DOI:10.1159/000182009
出版商:S. Karger AG
年代:1981
数据来源: Karger
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2. |
Progress from Haemodialysis |
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Nephron,
Volume 27,
Issue 1,
1981,
Page 2-6
S. Shaldon,
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PDF (957KB)
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ISSN:1660-8151
DOI:10.1159/000182010
出版商:S. Karger AG
年代:1981
数据来源: Karger
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3. |
Alternatives to Diffusion Dialysis: Is there a Need for a Better ‘Mousetrap’? |
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Nephron,
Volume 27,
Issue 1,
1981,
Page 7-8
Andrew P. Lundin,
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PDF (448KB)
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ISSN:1660-8151
DOI:10.1159/000182011
出版商:S. Karger AG
年代:1981
数据来源: Karger
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4. |
Activation of the Alternative Complement Pathway by Unidentified Substances in Human Glomerulonephritis |
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Nephron,
Volume 27,
Issue 1,
1981,
Page 9-14
F.P. Schena,
G. Pertosa,
E. Vox,
L. Bonomo,
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摘要:
Activation of the alternative complement pathway (AP) has been investigated in 79 serial serum samples obtained from 28 patients which had different types of glomerulonephritis. Serum factors activating the AP of the complement system have been detected in 12 patients with various forms of glomerulonephritis. Immune complexes (IC), levels of complement components of the classical and the alternative pathways and cobra venom factor activity were measured. Serum specimens were subcategorized as 2 study populations: (i) patients with serum factors activating AP and (ii) patients with both serum activators and IC. Although CoVF-AH50, properdin factor B and C3 concentrations were comparably depressed in these two groups, the levels of C1q and C4 were very low only in patients with circulating IC. These data were highly suggestive of AP activation due to serum factor. In contrast the patients also showing circulating IC had activation of both pathways. The presence of these factors suggests that renal damage can be determined by other immunological stimuli.
ISSN:1660-8151
DOI:10.1159/000182012
出版商:S. Karger AG
年代:1981
数据来源: Karger
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5. |
Post partumHaemolytic-Uraemic Syndrome Treated with Antithrombin-III |
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Nephron,
Volume 27,
Issue 1,
1981,
Page 15-18
Per Brandt,
Jørgen Jespersen,
Gunnar Gregersen,
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摘要:
A 34-year-old woman with a family history of pregnancy-associated thrombotic disease developed pre-eclampsia in her 8th month of pregnancy. A severe haemolytic-uraemic syndrome (HUS) developed within 24 h after spontaneous delivery. Because the plasma antithrombin-IΠ (AT-III) was only 15% of the normal concentration, an AT-III concentrate was given intravenously. When the normal level of plasma AT-III was reached, the clinical and biochemical signs of the syndrome disappeared. Renal function and biopsy were normal within 10 days. Because complete recovery is unusual in patients with post partum HUS and no previous reports have described a rapid recovery, the case reported here suggests that infusion of an AT-III concentrate should be tried when plasma AT-IIIis significantly decreased
ISSN:1660-8151
DOI:10.1159/000182013
出版商:S. Karger AG
年代:1981
数据来源: Karger
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6. |
Plasma Factor XIII Levels in Children with Renal Disease |
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Nephron,
Volume 27,
Issue 1,
1981,
Page 19-24
Kazuo Yoshioka,
Hiroshi Miyata,
Yoshihide Uraoka,
Sunao Maki,
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摘要:
Plasma levels of coagulation factor XIII determined quantitatively were found to have a tendency to be decreased in more severely affected cases of acute poststreptococcal glomerulonephritis and Henoch-Schönlein nephritis, and found to be decreased in patients with rapidly progressive glomerulonephritis and chronic renal failure in comparison with normal controls. It seems that the degree of decrease in factor XIII reflects the intensity of glomerular damage. In contrast, the patients with the nephrotic syndrome showed significant elevation of plasma factor XIII levels and it was closely correlated with the increase in serum triglycerides. The elevation of factor XIII levels in the nephrotic syndrome is suggested to be mainly attributed to enhanced protein synthesis in connection with urinary loss of proteins
ISSN:1660-8151
DOI:10.1159/000182014
出版商:S. Karger AG
年代:1981
数据来源: Karger
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7. |
Effect of Potassium Removal during Hemodialysis on the Plasma Potassium Concentration |
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Nephron,
Volume 27,
Issue 1,
1981,
Page 25-30
Peter U. Feig,
Alan Shook,
Richard H. Sterns,
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摘要:
The effect of potassium removal by hemodialysis on the plasma potassium concentration (PK) was observed during 20 studies on 7 anuric patients. The following was observed: (1) The pattern of change in PK is consistent with at least a two-compartment distribution; hence, in contrast to urea, PK shows a marked postdialytic rebound and the simple equation for solute removal from a single pool cannot predict postdialysis PK. (2) The magnitude of the fall in PK correlated with the predialysis PK; this was not only due to increased potassium removal, but also due to a dependence of the apparent volume of distribution of potassium on the state of potassium balance. The fractional decrement in plasma potassium concentration, contrary to that of urea, is a function of predialysis concentration, and prediction of the effect of dialysis on plasma potassium concentration can assume neither a single pool nor a constant distribution volume for this ion.
ISSN:1660-8151
DOI:10.1159/000182015
出版商:S. Karger AG
年代:1981
数据来源: Karger
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8. |
Evidence for Patchy Renal Vasoconstriction in Man: Observation by CT Scan |
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Nephron,
Volume 27,
Issue 1,
1981,
Page 31-34
Isao Ishikawa,
Yasuhito Saito,
Akira Shinoda,
Zengoro Onouchi,
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摘要:
We report the first demonstration of patchy vasoconstriction of the kidney in man, together with temporary impairment of renal function. Observations were made by computerized tomography (CT scan). Such vasoconstriction might occur during the mild form or the recovery phase of acute renal failure.
ISSN:1660-8151
DOI:10.1159/000182016
出版商:S. Karger AG
年代:1981
数据来源: Karger
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9. |
Tissue and Blood Cell Concentration of Methylguanidine in Rats and Patients with Chronic Renal Failure |
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Nephron,
Volume 27,
Issue 1,
1981,
Page 35-39
Yoshimasa Orita,
Akio Ando,
Yoshihiro Tsubakihara,
Hiroshi Mikami,
Takeo Kikuchi,
Kazuhiro Nakata,
Hiroshi Abe,
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摘要:
Methylguanidine concentration in blood cell of nondialysed patients with chronic renal failure was quantitatively determined by the method of the present authors. We also determined tissue methylguanidine concentrations in the liver, blood cell, kidney, colon, muscle and brain of uremic rat experimentally produced by Platt’s method. Methylguanidine concentrations in blood cell and tissues except the brain of the uremic rats and in blood cell of the uremic patients were 5–7 times higher than those in their serums. An increased methylguanidine concentration in the liver of the uremic rat receiving 40% protein diet was observed. These results imply that methylguanidine acts as one of the important uremic toxins in the intracellular space except for the brain, and suggest that the liver specifically affects the formation of methylguanid
ISSN:1660-8151
DOI:10.1159/000182017
出版商:S. Karger AG
年代:1981
数据来源: Karger
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10. |
On the Effect of Magnesium on the PTH Secretion in Uremic Patients on Maintenance Hemodialysis |
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Nephron,
Volume 27,
Issue 1,
1981,
Page 40-42
M. Gonella,
F. Bonaguidi,
G. Buzzigoli,
V. Bartolini,
G. Mariani,
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摘要:
The Mg, Ca and immunoreactive parathyroid hormone (PTH) serum levels were determined in 22 uremic patients on chronic hemodialysis with different Mg concentrations in the dialysate. Baseline levels of PTH, Ca and Mg were obtained over a 4-month-period whilst on Mg dialysis of 1.5 mEq/l. Patients were then divided into three groups: 10 patients were dialyzed for 6 months with 0.5 mEq/l of Mg, 7 patients with 1.5 mEq/l, and 5 patients with 2.5 mEq/l Mg. At the end of the 6-month period with differentiated Mg dialysis the three groups were characterized by significantly different Mg serum levels. On the contrary, no significant changes were observed in the PTH or the Ca serum levels. The results of this study indicate that PTH secretion in uremic patients on regular hemodialysis is not appreciably influenced by the Mg serum levels.
ISSN:1660-8151
DOI:10.1159/000182018
出版商:S. Karger AG
年代:1981
数据来源: Karger
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