摘要:

A new oral amino acid preparation was given to two groups of patients: group 1, five patients on hemodialysis; and group 2, five patients with chronic renal failure (CRF). In group 1 significant pre- and postdiet changes were: BUN 93–37 mg% (p < 0.01); creatinine 13.0–9.7 mg% (p < 0.001); phosphorus 6.6–4.2 mg% (p < 0.05); uric acid 8.7–6.0 mg% (p < 0.01); C0216.3–21.3 mEq/l (p < 0.01); hematocrit 18.0–20.8% (p < 0.05). In group 2: BUN 93–66 mg% (p < 0.05); phosphorus 5.6–3.8 mg% (p < 0.05); hematocrit 27.3–30.7% (p < 0.05). Nitrogen balance was positive in all patients. It is concluded that this oral amino acid mixture is well-tolerated and can be utilized in CRF to attain

ISSN:1660-8151    

DOI:10.1159/000180474

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

The effect of the length of hemodialysis on the outcome of renal transplant was evaluated in 43 recipients of renal allograft. 22 out of 23 patients (95.7%) dialyzed for longer than one year had an excellent renal function at one year, while only 10 out of 20 patients (50%) dialyzed for less than one year had good renal function at one year. Only one kidney (4.3%) was lost due to rejection in the first group, while 10 kidneys (50%) failed to function because of severe rejection in the second group. The length of hemodialysis appears to have a beneficial effect on graft survival, but the mechanism by which it exerts this effect is not clear.

ISSN:1660-8151    

DOI:10.1159/000180475

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

A group of patients whose dietary potassium was unrestricted and who received 12–18 h of Kiil dialysis twice weekly against a bath containing no potassium, had body potassium concentrations (total body potassium/intracellular volume) of 7.6% lower than normal. Despite marked hypokalemia at the end of dialysis, surprisingly few electrocardiographic changes were seen. Another group of subjects, dialyzed for 5–6 h thrice weekly against a bath containing 1 mEq/liter of potassium in a Dow dialyzer, showed more marked electrocardiographic abnormalities despite smaller alterations in transmembrane potassium gradients. Rapidity of establishment of potassium gradients is important as well as magnitude. The following changes occur in a single dialysis: 100 mEq of cell potassium and 20 mEq of extracellular potassium leave the body; 100 mEq of extracellular sodium enter the cells and 415 mEq of extracellular sodium leave the body; 3.5 liters of water leave the extracellular fluid, 2.5 liters into the bath and 1 liter into the ce

ISSN:1660-8151    

DOI:10.1159/000180476

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

Rats were kept for 4 weeks on a dietary regimen with a low or high sodium intake to increase or reduce, respectively, the renin activity of the kidneys and plasma. Fibrinolysis was inhibited by intravenous injection of AMCA and thrombin was infused into the jugular vein, giving rise to heavy intravascular fibrin deposition in the kidneys. Shortly after the thrombin infusion the glomerular filtration rate (GFR) decreased equally in saline-loaded and normal rats. 48 h after the thrombin infusion the GFR was still markedly reduced in saline-deprived and normal rats but had returned to preinfusion values in the saline-loaded rats. The results might indicate that the renin-angiotensin system is involved in the persistence of the renal functional impairment after intravascular coagulation in the rat kidney.

ISSN:1660-8151    

DOI:10.1159/000180477

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

Renin secretion has been hypothesized to be inversely related to the tubular sodium concentration or load. Using rat kidney cortex slices, in vitro renin secretion was measured as a function of sodium concentration of the medium. We found, as have many others, that renin secretion increases with increasing medium sodium concentration. However, in the presence of 10-3m ouabain, renin secretion decreased with increasing medium sodium concentration. We also found that intracellular sodium concentration varied directly with medium sodium both in the presence and absence of ouabain. Furosemide, a known renin stimulator in vivo, had no effect on renin secretion from tissue slices. Although obvious differences exist between in vitro and in vivo results, no simple relationship may exist between intracellular sodium concentration and renin secretion.

ISSN:1660-8151    

DOI:10.1159/000180478

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

Removal of excessive fluid with a negative-pressure hydrostatic ultrafiltration technique using a partial vacuum was performed successfully in eight patients. The technique appears to be a satisfactory means of fluid removal.

ISSN:1660-8151    

DOI:10.1159/000180479

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

A 62-year-old woman gave clinical manifestation of liver cirrhosis. Urinary protein was false positive, no uremia was found and renal changes were entirely overlooked. Deposition of abundant lipids (globoside and ceramide trihexoside) was found in the kidneys; essentially degenerative changes of the tubular epithelia were noted. These renal changes were compared with those in Fabry’s diseas

ISSN:1660-8151    

DOI:10.1159/000180480

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

Analysis of 47 renal biopsies performed on adult patients with nephrotic syndrome in Bahia, Brazil, shows a peculiar distribution of the histologic types with a preponderance of membranoproliferative glomerulonephritis. The possibility of a regional influence is discussed, particularly with regard to Schistosoma mansoni infection which is endemic in this area and probably an important cause of glomerulopathy.

ISSN:1660-8151    

DOI:10.1159/000180481

出版商:S. Karger AG    

年代:1975

数据来源: Karger

ISSN:1660-8151    

DOI:10.1159/000180482

出版商:S. Karger AG    

年代:1975

数据来源: Karger

ISSN:1660-8151    

DOI:10.1159/000180483

出版商:S. Karger AG    

年代:1975

数据来源: Karger