摘要:

We report a patient with pityriasis lichenoides et varioliformis acuta (PLEVA) with atypical clinical features, which was treated successfully with PUVA therapy. A 23-year-old man had discrete multiple erythematous scaly papules and patches on the trunk and extremities. New lesions developed abruptly within 1 month, forming generalized annular erythematous plaques with yellowish scales on the border. Skin biopsy specimens showed the typical histopathological findings of PLEVA. The skin lesions completely resolved with 8 months of PUVA therapy.

ISSN:0954-6634    

DOI:10.3109/09546639609089542

出版商:Taylor&Francis    

年代:1996

数据来源: Taylor

摘要:

A patient affected by dermatomyositis, who did not respond to conventional therapies (steroids alone and in association with immunosuppressive drugs), developed necrotic lesions in the axillary and antecubital folds. The lesions did not improve after increasing the steroid dose. Treatment with intravenous immunoglobulin (IVIG) at a dose of 1 g/kg daily for 2 successive days every 4 weeks was started. Ten days after the first infusion of IVIG the cutaneous lesions disappeared and in the following months the muscle symptoms improved as well. The patient was treated with ten cycles of IVIG and then at a maintenance dose of 1 g/kg over one day every third month. This treatment has been demonstrated to be effective, but it is necessary to underline the need for an accurate selection of patients. The cost of nine months of therapy for a patient of 55 kg in body weight is about±41 350 (L. 100 000 000).

ISSN:0954-6634    

DOI:10.3109/09546639609089543

出版商:Taylor&Francis    

年代:1996

数据来源: Taylor

摘要:

A validated measure of psoriatic severity is needed for effective treatment and research of the disease. The absence of such a measure has led many investigators to create their own methods of assessing psoriasis, while many others use such popular measurement techniques as the psoriasis area and severity index (PASI). Though few studies have been conducted to investigate the accuracy and usefulness of the PASI, investigators worldwide continue to use it in the evaluation of treatment. Investigators in the psychological sciences use an established set of measurement criteria (referred to as psychometrics) to evaluate and modify scales that measure psychological constructs. However, these same criteria also can be utilized in determining how well the PASI, as well as the various other methods of psoriatic assessment, measure severity. In this paper, the scale of properties of validity and reliability are discussed, including a review of the research addressing these properties within the PASI. Finally, a discussion of the future research needed in the assessment of psoriasis is provided.

ISSN:0954-6634    

DOI:10.3109/09546639609089544

出版商:Taylor&Francis    

年代:1996

数据来源: Taylor

ISSN:0954-6634    

DOI:10.3109/09546639609089545

出版商:Taylor&Francis    

年代:1996

数据来源: Taylor

ISSN:0954-6634    

DOI:10.3109/09546639609089546

出版商:Taylor&Francis    

年代:1996

数据来源: Taylor

摘要:

Wound Healing and Skin Physiology: P Altmeyer, K. Hoffman, S el Gammal, J Hutchinson (eds), Springer, BerlinCosmetic Dermatology: R Baran&HI Maibach (eds), Martin Dunitz, London

ISSN:0954-6634    

DOI:10.3109/09546639609089547

出版商:Taylor&Francis    

年代:1996

数据来源: Taylor

ISSN:0954-6634    

DOI:10.3109/09546639609089548

出版商:Taylor&Francis    

年代:1996

数据来源: Taylor