摘要:

Pyoderma gangrenosum is a deep necrotizing, ulcerative skin disorder. Surgery is complicated not only by the primary disease process but also by the systemic treatment instituted for it. We report here the successful treatment by mastectomy and latissimus dorsi myocutaneous flap reconstruction of a lobular breast cancer in a patient who presented with acute pyoderma gangrenosum of the breast.

ISSN:0954-6634    

DOI:10.3109/09546639409080571

出版商:Taylor&Francis    

年代:1994

数据来源: Taylor

摘要:

Two patients with CREST syndrome were treated for their telangiectases of the face with a Candela SPTL-1 flash-lamp pulsed dye laser. The results were highly satisfactory in both patients. No side-effects were observed, and no patient displayed signs of disease activation.

ISSN:0954-6634    

DOI:10.3109/09546639409080572

出版商:Taylor&Francis    

年代:1994

数据来源: Taylor

摘要:

A group of 17 men and 3 women with genital warts in which DNA/RNA phenotyping was performed were treated with intralesional interferon alpha-2a (1 MU/cm2) three times weekly for 3 weeks. Treatment was followed by a 16-week observation period. Interferon alpha-2a treatment resulted in a highly significant reduction in the mean size of the warts, which decreased from an initial size of 37 mm2to 4–5 mm2by week 16 (P<0.05). The response appeared to depend on the human papillomavirus (HPV) genotype. Patients with types 6 or 11 showed good responses in 11 of the 12 cases. The response in HPV types 16 and 18 infection was poor in 4 of the 8 cases. During follow-up (mean 4 months) no recurrence was observed. Intralesional treatment showed minimal side-effects. We conclude that intralesional interferon alpha-2a is useful in the treatment of genital warts caused by HPV of types 6 and 11.

ISSN:0954-6634    

DOI:10.3109/09546639409080573

出版商:Taylor&Francis    

年代:1994

数据来源: Taylor

摘要:

An open study was performed on seven patients with delayed pressure urticaria. All the patients were submitted to a gluten-free diet. Dramatic results were obtained within 4 to 10 days in six patients with a recurrence of symptoms after gluten ingestion in five patients. Investigations for a relationship between gluten and delayed pressure urticaria were negative. We report here the preliminary results.

ISSN:0954-6634    

DOI:10.3109/09546639409080574

出版商:Taylor&Francis    

年代:1994

数据来源: Taylor

摘要:

Editorial commentDermatology trainees need to be familiar with azathioprine as this drug is an important immunosuppressive agent used in a variety of different dermatological conditions. This article covers both the licensed and unlicensed indications for azathioprine and outlines the metabolic fate of this drug in relation to safety and efficacy. Guidelines concerning pre-treatment counselling of patients, dosage and monitoring for side-effects are included. Trainees should be aware that long-term use of azathioprine has been implicated as a co-factor in the development of skin neoplasia and in non-cutaneous malignancy.

ISSN:0954-6634    

DOI:10.3109/09546639409080575

出版商:Taylor&Francis    

年代:1994

数据来源: Taylor

ISSN:0954-6634    

DOI:10.3109/09546639409080576

出版商:Taylor&Francis    

年代:1994

数据来源: Taylor

摘要:

Colour Guide—Dermatology: JD Wilkinson, S Shaw&DA Fenton, Churchill Livingstone, 1993, 158 pages,£8.95. ISBN: 0-443-04629-8.Cutaneous Drug Reactions: An Integral Synopsis of Today's Systemic Drugs, 2nd edn.: K Zurcher&A Krebs, Karger, Basel, 1992, 570 pp,£215.70. ISBN: 3-8055-4939-3.

ISSN:0954-6634    

DOI:10.3109/09546639409080577

出版商:Taylor&Francis    

年代:1994

数据来源: Taylor

ISSN:0954-6634    

DOI:10.3109/09546639409080578

出版商:Taylor&Francis    

年代:1994

数据来源: Taylor