摘要:

We report fatal hepatocellular failure in two patients who had received cytotoxic therapy for skin disease. Both patients were found to be hepatitis B carriers when investigated during their illness. We feel this contributed significantly to their hepatic damage.

ISSN:0954-6634    

DOI:10.3109/09546639009086750

出版商:Taylor&Francis    

年代:1990

数据来源: Taylor

摘要:

Curly fingernails developed in a 35-year-old female during etretinate therapy (0.25 mg/kg per day) given for chronic palmoplantar pustulosis. Before treatment some of the fingernails showed slight distal onycholysis without dystrophy or irregularity of the nail plate. The suggested mechanism of this phenomenon is a stimulatory effect on nail growth rate expressed on normal matrix differentially from matrix with pre-existing pathology.

ISSN:0954-6634    

DOI:10.3109/09546639009086751

出版商:Taylor&Francis    

年代:1990

数据来源: Taylor

摘要:

Surgery is of significant benefit in regional metastases and in selected cases of solitary visceral metastasis. The chief use of radiotherapy is in central nervous system and osseous metastases. Chemotherapy and immunotherapy have, to date, been disappointing but perhaps have more hope for the future. It is important, however, that management is balanced, and that patients are not submitted to toxic and distressing regimes on the basis of unrealistic hopes.

ISSN:0954-6634    

DOI:10.3109/09546639009086752

出版商:Taylor&Francis    

年代:1990

数据来源: Taylor

摘要:

This paper discusses some of the steps which can be taken to try to prevent the development of skin cancer. These steps are relatively simple, and should not be so onerous as to restrict work or recreation outdoors.

ISSN:0954-6634    

DOI:10.3109/09546639009086753

出版商:Taylor&Francis    

年代:1990

数据来源: Taylor

摘要:

The focus of attention regarding the side-effects of PUVA therapy has mainly been its potential carcinogenesis. Short-term adverse effects are less commonly reported. A review is given of adverse effects reported in the literature. The majority of reports deal with psoralen-induced adverse reactions from 8-methoxypsoralen. A minority of the reports deal with actual PUVA-related adverse effects, requiring UVA irradiation as well as the ingestion of the drug. Prompt recognition of these phenomena is of importance to the patient as they may have immediate implications for continued photochemotherapy.

ISSN:0954-6634    

DOI:10.3109/09546639009086754

出版商:Taylor&Francis    

年代:1990

数据来源: Taylor

ISSN:0954-6634    

DOI:10.3109/09546639009086755

出版商:Taylor&Francis    

年代:1990

数据来源: Taylor

摘要:

Management of Blistering Diseases Eds. F Wojnarowska&RA Briggaman. Chapman and Hall Medical, London, 1990, 320 pages,£65.00, ISBN: 0-4122-8990-3.

ISSN:0954-6634    

DOI:10.3109/09546639009086756

出版商:Taylor&Francis    

年代:1990

数据来源: Taylor