摘要:

An experimental study on rabbit sclerosing cholangitis (SC) secondary to direct injection into the biliary tract of the chemical substances commonly employed for intraoperative sterilization of the hydatid cyst content is reported. Among the various substances utilized, 10% formalin and 30% hypertonic solution caused gross and microscopic lesions compatible with less advanced forms of sclerosing cholangitis. The authors present their hypothesis on the development of SC in operated hydatid cysts of the liver.

ISSN:0014-312X    

DOI:10.1159/000128786

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

The role of the adrenergic system in the duodenal mechanisms that inhibit gastric acid secretion (GAS) after duodenal acidification (DA) was studied. In 12 mongrel dogs, with gastric and duodenal fistulas, six experiments were carried out evaluating penta-gastrin-stimulated GAS and serum secretin levels: DA (HC12 ml/min) for 1 h (group A); DA (HC12 ml/min) for 1 h plus propranolol (group B); DA (HC1 2 ml/min) for 1 h plus phentolamine (groupt C); duodenal instillation of saline (2 ml/min) for 1 h (group D); (duodenal instillation of saline (2 ml/min) for 1 h plus propranolol (group E), and duodenal instillation of saline (2 ml/min) for 1 h plus phentolamine (group F). Significantly (p < 0.05) high percentages of inhibition of GAS (49–70.5%) paralleled with increases of serum secretin levels (48.4–84%) were noted in group A and C experiments. However, DA did not inhibit GAS nor did it increase the levels of secretin in group B and D-F experiments. It is concluded that the inhibition of GAS after DA is controlled, at least in part, by the action of the β-adrenorecep

ISSN:0014-312X    

DOI:10.1159/000128787

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

Regional cerebral blood flow (rCBF) was studied in anesthetized dogs subjected to acute left ventricular failure and its treatment with enalaprilat (MK-422). When failure was induced a reduction in rCBF paralleling the reduction in systemic blood pressure was observed. After treatment rCBF did not change in spite of further blood pressure reduction. The results are explained by changes in vascular resistance of larger cerebral arteries. Vasoconstriction in these vessels during failure was counteracted by enalaprilat through reduction in circulating angiotensin II.

ISSN:0014-312X    

DOI:10.1159/000128788

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

The two-component tissue adhesive system where the one component is a concentrated human fibrinogen solution and the other component is a thrombin solution containing Ca2+ is becoming increasingly important in surgery. In the commercially available tissue adhesive, the fibrinogen is separated from pooled plasma. The risk of transmitting foreign immunogens and viruses, always present when foreign biological materials are used, will be eliminated if the fibrinogen is separated from the patient’s own blood. A method using ethanol precipitation is described for preparing a concentrated fibrinogen solution from plasma separated from small amounts of blood. The method is fast, the final product can be obtained within 30–60 min after collection of the blood. The recovery is compared with the recovery obtained by separating the fibrinogen with ammonium sulfate precipitation and with cryoprecipitation. The method using ethanol is by far the most profitable, and the product is evaluated by experimental liver surgery in p

ISSN:0014-312X    

DOI:10.1159/000128789

出版商:S. Karger AG    

年代:1988

数据来源: Karger

ISSN:0014-312X    

DOI:10.1159/000128790

出版商:S. Karger AG    

年代:1988

数据来源: Karger

ISSN:0014-312X    

DOI:10.1159/000128791

出版商:S. Karger AG    

年代:1988

数据来源: Karger

ISSN:0014-312X    

DOI:10.1159/000128792

出版商:S. Karger AG    

年代:1988

数据来源: Karger

ISSN:0014-312X    

DOI:10.1159/000128793

出版商:S. Karger AG    

年代:1988

数据来源: Karger

ISSN:0014-312X    

DOI:10.1159/000128775

出版商:S. Karger AG    

年代:1988

数据来源: Karger