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21. |
DENIAL OF CHRONIC PAIN-A DISTURBING NEW MANAGEMENT PARADIGMA Commentary1 |
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American Journal of Physical Medicine and Rehabilitation,
Volume 78,
Issue 1,
1999,
Page 83-84
Robert Teasell,
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ISSN:0894-9115
出版商:OVID
年代:1999
数据来源: OVID
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22. |
WEANING FROM MECHANICAL VENTILATION IN A GENERAL REHABILITATION CENTERA Commentary1 |
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American Journal of Physical Medicine and Rehabilitation,
Volume 78,
Issue 1,
1999,
Page 85-86
Octave Merveille,
Martin Childers,
Mosbah Kreimid,
William George,
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ISSN:0894-9115
出版商:OVID
年代:1999
数据来源: OVID
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23. |
USE OF SEQUENTIAL MEDICAL TRIALS IN REHABILITATION RESEARCH1 |
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American Journal of Physical Medicine and Rehabilitation,
Volume 78,
Issue 1,
1999,
Page 87-97
Leigh Tooth,
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摘要:
Although randomized, clinical trial designs represent the pinnacle of research excellence, they are often difficult to implement in natural or clinical settings. An alternative approach to analysis of data collected during rehabilitation research is the sequential medical trial design. In a sequential medical trial, subjects are serially recruited and the results are continuously analyzed. The use of preconstructed sequential charts remove the need for clinicians to perform complicated statistical analyses and allow an immediate visual indication of the direction the results are taking. Benefits of sequential medical trials are as follows: as soon as enough data are collected to show treatment preference, the trial is stopped; a trial that is showing no beneficial or even harmful effects can be quickly terminated; fewer subjects are needed (without loss of statistical power); features such as randomization, blinding, and cross-over designs can be included; the design suits the serial nature of rehabilitation practice. Limitations to sequential medical trials are that in simple designs extraneous factors cannot be controlled for and that multiple dependent variables are difficult to assess. This article discusses the theory behind the sequential medical trial design and outlines how to plan a sequential medical trial, recruit subjects, construct and use a simple sequential chart, and analyze and interpret the results. Examples of sequential medical trials used in rehabilitation research are presented. It is hoped that this article will increase the exposure of this useful design and result in greater use of sequential medical trials by rehabilitation professionals.
ISSN:0894-9115
出版商:OVID
年代:1999
数据来源: OVID
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24. |
CME SELF-ASSESSMENT EXAM-ANSWERSAmerican Journal of Physical Medicine & Rehabilitation Vol. 78, No. 1, January/February 1999 |
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American Journal of Physical Medicine and Rehabilitation,
Volume 78,
Issue 1,
1999,
Page 97-97
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ISSN:0894-9115
出版商:OVID
年代:1999
数据来源: OVID
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25. |
News and Notes |
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American Journal of Physical Medicine and Rehabilitation,
Volume 78,
Issue 1,
1999,
Page 98-98
&NA;,
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ISSN:0894-9115
出版商:OVID
年代:1999
数据来源: OVID
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26. |
Calendar of Events |
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American Journal of Physical Medicine and Rehabilitation,
Volume 78,
Issue 1,
1999,
Page 99-99
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ISSN:0894-9115
出版商:OVID
年代:1999
数据来源: OVID
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