ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1981.tb01903.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1981.tb01905.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1981.tb01906.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

ABSTRACT.Forty‐five high risk infants were examined in a neonatal nursery with a real‐time ultrasound scanner. The relevant normal and abnormal intracranial features are described. There was a good correlation betwen the site and size of the 12 intraventricular haemorrhages (IVH) found on ultrasound scanning with subsequent computerised axial tomography (CAT) scans and postmortem results. There was also close agreement between CAT and ultrasound scan assessment of ventricular size. Our data suggest that IVH occurs within the first 48 hours of life. In the light of our experience and because of its convenience and safety we have largely abandoned CAT scanning in favour of real‐time ultrasound scanning in the investigation of neonatal IVH and hydroce

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1981.tb01907.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1981.tb01908.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

ABSTRACT.Cephamandole pharmacokinetics during the first week of life, in term neonates, have been defined. The results of these studies allow a dosage recommendation of 25 mg/kg 12 hourly intravenously or 8 hourly intramuscularly. Cephamandole when administered intramuscularly was shown to be bioavailable (80.9 ± 16.4%)

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1981.tb01909.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

ABSTRACT.In this study of the effects of death of a child from malignancy on the immediate family, it was found that 62 of 93 families wished to participate and that, in 50%, there was evidence of family dysfunction. Factors that appeared to be associated with dysfunciton included older parental age, lower educational achievement, previous social and psychological disturbances, poor family communication and lack of support from within the family by one or other of the parents. In 45% of the families, one or other sibling showed an abnormality of behaviour which was usually transient. The deceased children in the study had not been informed of their imminent death. In those families in which the parents perceived that their child knew that he was dying, there was a significantly higher incidence of family disturbance. In the absence of prospective clinical trials on the effects on the child and the family of informing the child that he was dying, it is not possible to draw conclusions on the above finding.

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1981.tb01910.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

ABSTRACT.Pancreatic extracts even in high doses usually fail to completely control steatorrhoea in cystic fibrosis (CF). Trypsin and lipase are rapidly and irreversibly inactivated by acid. Twenty‐two patients with CF entered a cross‐over trial where they received their usual dose of pancreatic extracts for four weeks, cimetidine plus pancreatic extracts for four weeks, and antacid plus pancreatic extracts for four weeks. There was a significant reduction (p<0.05) in mean faecal fat excretion of 15.36 ± 8.54 g/day, and an improvement of the coefficient of absorption 78.2 ± 12.1% (p<0.02) during the treatment period with pancreatic extracts alone to 12.48 ± 7.26 g/day and 83.2 ± 8.0% respectively with pancreatic extracts plus cimetidine. There was a significant improvement of the coefficient of absorption during the pancreatic extracts alone treatment period from 78.2 ± 12.1% to 82.6 ± 7.2% during the treatment period with pancreatic extracts plus antacid (p<0.05). None of the treatments differed in their effects on weight gain, stool frequency and subjective variables (stool odour and consistency, abdominal pain an

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1981.tb01911.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

ABSTRACT.Fifteen patients with broken, and one patient with retained, rectal thermometers were reviewed. All were below the age of five. Histories of struggling in older children and difficult insertion of the thermometers in infants were often present. Rectal examination was definite in identifying the foreign bodies in seven patients. X‐ray was diagnostic in eight patients. None had any peritonitis or perforation. Five patients had rectal bleeding which subsided in three days. In the three patients who had procto‐sigmoidoscopic examination, all showed abrasions of the anterior rectal w

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1981.tb01912.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

ABSTRACT.The effect of skilled transport on the condition of 100 infants referred for intensive care and the factors affecting their survival were analysed. Infants with respiratory failure who were not moribund showed significant increases in pH (P<0.01) and arterial/alveolar P02 ratio (P<0.001) with assisted ventilation. Less severely ill infants were transported without significant change in pH and blood gas status. Hypoxaemia (17%), hyperoxaemia (24%) and hyperglycaemia (14%) were not uncommon on admission to the newborn intensive care unit.Survival rate did not decrease significantly with decreasing birth weight or gestation. Factors significantly more common in infants who died were one minute Apgar score 0–3 (P<0.05), and pH<7.25 (P60 mmHg (P<0.005) on admission to the NICU. Infants mechanically ventilated before transport did not have a significantly higher mortality rate than those ventilated after admission, though moribund infants and those with untreated early onset bacterial pneumonia had high mortality rates.Pre‐transfer events were responsible for the death of 8 (38%) of the 21 infants who died and perhaps contributed to the death from intraventricular haemorrhage of a further 5 infants (2

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1981.tb01913.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY