摘要:

Haan, E. A., Danks, D. M., Hoogenraad, N. J., and Rogers, J. G. (1979).Aust. Paediatr. J.,15, 142–146. Hereditary hyperammonaemic syndromes. A six year experience.Over a six year period (1973–1978) we have managed 13 children with hereditary hyperammonaemia. Nine of these had ornithine transcarbamylase deficiency. Early recognition and treatment of hyperammonaemia is necessary for salvage of infants capable of survival. In children whose disease is lethal, aetiologic diagnosis should be made for the purposes of genetic counselling, carrier detection and prenatal diagno

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1979.tb01212.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Yu, V. Y. H., James, B. E., Hendry, P. G. and MacMahon, R. A. (1979).Aust. Paediatr. J.,15, 147–151 Glucose tolerance in very low birthweight infants.The carbohydrate intake and incidence of hyperglycaemia were reviewed in 40 very low birthweight infants with a birthweight of less than 1200g who were randomly assigned to total parenteral nutrition (TPN) or oral (MILK) feeding regimens during the first two weeks after birth. With increasing glucose tolerance after birth, the carbohydrate intake was increased from a mean intake of 8g/kg.d on Day 1 to 17g/kg.d in the TPN group and 12g/kg.d in the MILK group by the second week; the lower intake in the latter group was due to a restricted intake rather than decreased glucose tolerance. Twenty‐seven per cent of the infants had moderate or severe hyperglycaemia in the first week compared with 13% in the second week, in spite of the higher carbohydrate intake in the latter period. All hyperglycaemic episodes were corrected promptly without obvious serious sequelae by decreasing the rate of carbohydrate intake. The rational approach to carbohydrate administration in the very low birthweight infant includes the calculation of carbohydrate intake in terms of g/kg.d (rather than arbitrary concentrations given at variable rates based on fluid requirement), a constant infusion at a steady rate, and the close monitoring of blood glucose to establish glucose tolerance limits which increase with postnatal

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1979.tb01213.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Yu, V. Y. H., and Hollingsworth, E. (1979).Aust. Paediatr. J.,15, 152–159. Respiratory failure in Infants weighing 1000 g or less at birth.The prognosis for infants weighing<1000 g has improved coincident with the improved ventilatory support in their neonatal management. There are many problems leading to respiratory failure which are particularly significant and peculiar to these infants. Of the 55 infants weighing<1000 g admitted in 1977 and 1978, 58% had hyaline membrane disease and 69% had preterm recurrent apnoea. Fifty‐one infants required assisted ventilation, or whom 28 were ventilated from birth. Though these infants could be ventilated successfully with low peak airway and positive end‐expiratory pressures, 52% of the ventilated infants required it for more than seven days, despite the use of intermittent mandatory ventilation and continuous positive airway pressure during weaning. The neonatal survival rate for assisted ventilation in infants weighing<1000 g was 57%. Seventeen of the ventilated infants developed pulmonary interstitial emphysema, a condition which was associated with an increased incidence of pneumothorax (four infants) and bronchopulmonary dysplasia (ten infants). Infants recovering from bronchopulmonary dysplasia required up to 76 days of assisted ventilation and 84 days of oxygen therapy. No major handicaps were detected on follow‐up except for one infant with retrolental fibroplasia. Optimal management of respiratory failure in infants weighing<1000 g can now result in increased survival with morbidity approaching those of larger preterm infants. As our knowledge, skills, techniques and equipment continue to improve, so will survival and morbidit

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1979.tb01214.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Tudehope, D. I., and Symth, Margaret H. (1979).Aust. Paediatr. J.,15, 160–165. Is “transient tachypnoea of the newborn” always a benign disease? Report of 6 babies requiring mechanical ventilation.A retrospective study in an intensive care nursery revealed that transient tachypnoea of the newborn (TTN) was the commonest cause of respiratory distress. This condition was frequently associated with marginal prematurity, hypoproteinaemia, birth asphyxia, Caesarean section, breech presentation and male babies. The signs associated with TTN abated by 48 hours in 74% of the babies; the remainder had a prolonged, often complicated course. Six of the nine babies with signs persisting more than 46 hours required mechanical ventilation; three because of hypoxaemia and three with severe respiratory acidosis. Babies with the clinical signs and radiographic features consistent with TTN may develop severe ventilation‐perfusion imbalance, fatigue and pulmonary hypertension with right to left shunting of blood across the ductus art

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1979.tb01215.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Kemp, A. S., and Holsman, P. D. (1979).Aust. Paediatr. J.,15, 166–167. Enumeration of mucus‐containing cells, mast cells and eosinophils in nasal smears from atropic children.The nasal smear cyctology from a group of immediate hypersensitivity skin test positive children with the symptom of recurrent wheeze was compared with that of a group of skin test negative children. Mucus‐containing cells, eosinophils and mast cells were quantitated. Eighteen of the twenty smears from the skin test positive children showed increased numbers of at least one cell type. It is concluded that abnormal nasal cytology is a common finding in atopic children with recurrent wheeze and that nasal pathology may be reflected in increased numbers of mucus‐containing cells, mast cells or eosi

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1979.tb01216.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Anyon, C. P., and Fletcher, T. G. (1979).Aust. Paediatr. J.,15, 168–169. Prevalence of wheezing in pre‐school children in Lower Hutt.An epidemiological study of pre‐school children in the Hutt Valley has been made. The prevalence of wheezing has been found to be 26%. Wheezing is a common cause of morbidity in Hutt Valley and, presumably, New Zealand chi

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1979.tb01217.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Reddihough, Dinah S. and Court, J. M. (1979).Aust. Paediatr. J.15, 170–172 Adolescents in Hospital.A study was undertaken to explore the needs of adolescents cared for in a large children's hospital. A questionnaire was given to one hundred teenaged patients, and time was also spent in discussion with them. Problems perceived by the adolescent patient in a children's hospital included disturbance at night by younger children, inadequate provision for secondary schooling, inadequate privacy, inappropriate meal times and insufficient recreational activities. Teenagers wanted a suitably furnished room set aside for recreation and also expressed need for opportunity to discuss their illness and treatment with staff.It is concluded that there should be greater awareness of the needs of adolescents in hospitals originally designed for younger children, and that even quite minor changes in ward design and hospital routine could meet these need

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1979.tb01218.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Hockey, Athel, and Bain, Jill (1979).Aust. Paediatr. J.,15, 173–176. The intellectually handicapped mother and her child.This paper presents information on the intellectually handicapped mother with regard to numbers, mode of ascertainment, diagnosis, intelligence, number of children born, intelligence and outcome for the child. It assesses the role of genetic counselling and its limitations in this field. It defines the most appropriate form early intervention for the offspring to offset or prevent handicaps. Cases are used to illustrate and discuss the effect of assortive mating: the difficulty of defining risk to a person, herself affected, and of expecting a reasoned decision; joint plans to follow up and assist in the care of the children by Child Health Services and the Division for the Intellectually Handicapped.Reasons are given for the conclusion that an eugenic approach is inappropriate here. Instead, genetic counselling and family planning, with practical training in child rearing are the main resource

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1979.tb01219.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Feery, B. J., Matthews, R. N., Evered, M. G., and Gallichio, H. A. (1979).Aust. Paediatr. J.,15, 177–180. Antibody responses to influenza virus vaccine in children with acute lymphocytic leukaemia.Antibody responses to influenza immunization in children with acute lymphocytic leukaemia in remission were studied in two successive years. Initial antibody levels, the response to immunization, and final antibody levels were lower than in a group of children with cystic fibrosis. The results indicate that both primary and anamnestic antibody responses are depressed in children with acute leukaemia when they are on immunosuppressive therapy. Despite this depression the majority of the patients reached protective antibody levels to the A/Victoria/3/75 and A/Texas/1/77 (H3N2) antigens but not to the recent A/USSR/90/77 (H1N1) antigen

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1979.tb01220.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Feery, B. J., Phelan, P. D., Gallichio, H. A., and Hampson, A. W. (1979).Aust. Paediatr. J.,15, 181–182. Antibody responses to influenza virus vaccine in patients with cystic fibrosis.Patients with cystic fibrosis were immunized with subunit influenza vaccine, and their haemagglutination‐inhibiting (HI) antibody responses were compared with responses in young healthy adults. There was no significant difference in the antibody levels reached after immunization and no evidence of any impairment of responses in the patient gr

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1979.tb01221.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY