ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1992.tb02705.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1992.tb02706.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1992.tb02707.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1992.tb02708.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

AbstractAt the Royal Children's Hospital, Melbourne, extracorporeal membrane oxygenation (ECMO) has been used in the treatment of newborn infants with life‐threatening respiratory or cardiac failure since May 1989. The main indications for the use of ECMO are that the disease is reversible, the surviving infant is likely to be normal and there is an 80% likelihood of death without ECMO. Sixteen of 22 (73%) newborn infants have survived at least 6 months after ECMO. Fourteen of 16 (87.5%) infants receiving ECMO (who did not have a congenital diaphragmatic hernia) were functionally normal survivors; the other two infants died. Two of six infants with congenital diaphragmatic hernia who received ECMO were discharged and survived to have normal neurological and respiratory function at 6 month follow up. These results are similar to results from other centres internationally. It would appear that ECMO is a useful therapy for near‐term newborn infants with otherwise fatal cardiorespiratory fail

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1992.tb02709.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

AbstractExtracorporeal membrane oxygenation (ECMO) has been used at the Prince of Wales Children's Hospital, Sydney for the treatment of newborn infants with life‐threatening respiratory or cardiac failure since August 1989. The main indications are that the disease is reversible, the surviving infant is likely to be normal and there is an 80% likelihood of death without ECMO. Eighteen of 19 newborn infants have survived at least 2 months after ECMO. The 15 infants receiving ECMO (nine with meconium aspiration, six with persisting pulmonary hypertension) who did not have a congenital diaphragmatic hernia were normal survivors. One death occurred at 5 months of age from chronic lung disease. Three of four infants with congenital diaphragmatic hernia were discharged following ECMO and appeared normal at 6,9 and 18 months of age. These results are similar to results from other centres internationally. It appears that ECMO is a useful therapy for near‐term newborn infants with otherwise fatal cardiorespiratory fail

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1992.tb02710.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

AbstractSerum osteocalcin was measured by radioimmunoassay in 200 normal children and adolescents, and seven growth hormone (GH) deficient and seven non‐growth hormone deficient (NGHD) short children. There was a sex‐ and age‐dependent change in the serum osteocalcin concentrations in normal children and adolescents with a pattern similar to the childhood height velocity curves. The serum osteocalcin concentration was in the low normal range in most patients with GH deficiency and NGHD short stature. GH therapy significantly increased the growth velocity in both groups of short children. GH treatment resulted in a significant rise in serum osteocalcin concentrations after 6 and 12 months in NGHD children but a more variable change was observed in GH‐deficient children. Although osteocalcin levels may give some biochemical indication of growth, these measurements should be used together with auxological and other biochemical measurements to assess growth r

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1992.tb02711.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

AbstractA new method of fixation of umbilical catheters is described. This method utilizes a purse‐string suture around the cord stump, which is then secured through the umbilical skin and fixed to the catheter with adhesive tape. This method avoids damage to the fragile skin, particularly of the preterm newborn, caused by the use of T piece strappin

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1992.tb02712.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

AbstractThe geographical distribution of child injury morbidity in Auckland between 1982 and 1987 was examined. Analysis of total injury, pedestrian injury and vehicle occupant injury, with the census area unit as the basic spatial entity revealed distinct variations in child injury morbidity by census area unit. Morbidity rates were above average in parts of the central urban area and South Auckland and below average on the North Shore. Total injury morbidity and pedestrian injury morbidity rates were strongly correlated with census area unit unemployment rates, which were used as a measure of socio‐economic deprivation. Geographical areas with high rates of child injury morbidity, to which injury prevention resources can be directed, were identified. In particular, the results suggest that injury prevention programmes should be targeted at socio‐economically disadvantaged communit

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1992.tb02713.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

AbstractThe efficacy of Ketotifen was examined in the treatment of 113 infants between 6 and 36 months of age presenting with a history of cough and/or wheeze in a multicentre randomized placebo‐controlled double‐blind study. A 4 week no‐medication baseline phase preceded the 16 week treatment phase in which infants took 2.5 mL twice daily of either placebo or Ketotifen (0.5 mg) syrup; this was followed by a 4 week wash‐out phase. Diary card evaluation was performed by the parent or guardian for the duration of the study and recorded wheeze and cough twice daily as well as medication used. The percentage of symptom‐free days decreased significantly in both groups (P<0.005) with placebo‐treated infants experiencing significantly more symptom‐free days compared with the Ketotifen group (P<0.01), although this difference was never more than 10% in any 4 week treatment period. Symptom severity scores and use of β‐agonist medication were also less in the placebo‐treated infants but did not reach statistical significance. This study was unable to show a therapeutic advantage of Ketotifen over placebo in this group of infants with chronic cough and/or wheeze and the apparent statistical advantage of placebo is not a clinicall

ISSN:1034-4810    

DOI:10.1111/j.1440-1754.1992.tb02714.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY