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11. |
Neuropathic Pain in a Cancer Patient Responding to Subcutaneously Administered Lignocaine |
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The Clinical Journal of Pain,
Volume 9,
Issue 3,
1993,
Page 220-223
Jacques,
Raymond Devulder Lydie,
Ghys Willy,
Dhondt Georges,
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摘要:
Objective: To demonstrate difficulties encountered in alleviating neuropathic pain in a terminally ill cancer patient, with the very tentative diagnosis of postherpetic neuralgia.Setting: A multidisciplinary pain department in a university hospital.Patients: A patient with Hodgkin's lymphoma and leiomyosarcoma in the liver developed an unusual manifestation of neuropathic pain.Intervention: Oral drug treatment with morphine associated with amitriptyline, valproic acid, mexilitine, flufenazine, and methylprednisolone failed to suppress pain attacks. Only the subcutaneous instillation of lidocaine (2 mg/kg/h) could partially suppress pain. A dorsal root entry zone lesion intervention could only temporary stop the pain attacks. Infiltration and nervous stimulation techniques were not helpful.Outcome Measures: In determinating pain control, the visual analog scale rating scale and the number of attacks per hour were considered.Results: Only the subcutaneous administration of lignocaine could partially suppress pain. Because of the patient's poor hepatic circulation, variable lidocaine plasma concentrations were responsible for intolerable side effects.Conclusions: Subcutaneous lignocaine administration remains a useful method in treating neuropathic cancer pain. The poor metabolic condition of the patient can lead to deleterious high plasma levels. A dorsal root entry zone lesion could only temporarily stop the pain.
ISSN:0749-8047
出版商:OVID
年代:1993
数据来源: OVID
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12. |
American Chronic Pain Association Workbook Manual |
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The Clinical Journal of Pain,
Volume 9,
Issue 3,
1993,
Page 224-224
Janet,
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PDF (61KB)
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ISSN:0749-8047
出版商:OVID
年代:1993
数据来源: OVID
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13. |
Announcements |
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The Clinical Journal of Pain,
Volume 9,
Issue 3,
1993,
Page 225-225
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PDF (128KB)
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ISSN:0749-8047
出版商:OVID
年代:1993
数据来源: OVID
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