摘要:

For over a decade there has been concern about hepatitis related to halothane anesthesia. No dose relationship or other direct cause has ever been established, and jaundice has been found to occur after other anesthetics for surgical operations. Enflurane is a newer halogenated compound with a remarkable record of safety, yet a few cases of hepatitis are reported to be associated with its administration. We have compared effects on the liver of the two anesthetics by testing hepatic serum enzymes and sulfobromophthalein in 12 patients who received halothane and 12 who received enflurane. No significant differences between the two groups were found. Both had similar but minimal elevations of the hepatic serum enzymes and retention of sulfobromophthalein. More than half the patients had enzyme increases over normal levels but reasons for this were not obvious. Since hepatic change may take place in many postoperative patients, it is not surprising to have an occasional one develop hepatitis. The exact cause is unknown and therefore it is impossible to predict the patient who will develop the disease, regardless of the anesthetic.

ISSN:0038-4348    

出版商:OVID    

年代:1978

数据来源: OVID

摘要:

Considerable effort has been made to improve endotracheal tubes and make them safer than they have been in the past; yet complications continue to occur, due, in most' instances, to inherent defects in the tube. It is not possible to identify these defects in a routine preoperative examination. Three cases are presented illustrating how defects in anode endotracheal tubes almost caused fatalities during anesthesia. Other possible complications and contributing factors causing obstruction of endotracheal tubes are also reviewed. Until some way is devised for the automatic compensation of the increases in volumes and pressures in endotracheal tube cuffs, hourly deflation is recommended to prevent complications.

ISSN:0038-4348    

出版商:OVID    

年代:1978

数据来源: OVID

摘要:

Federal (FDA) regulations recently passed require physician clearance before hearing aid sales. Discussed herein are numerous evaluative and rehabilitative procedures necessary for proper hearing aid fittings. A program of total professional management of the hearing rehabilitation process, including the direct dispensing of hearing aids by the otology-audiology team, is described and advocated.

ISSN:0038-4348    

出版商:OVID    

年代:1978

数据来源: OVID

摘要:

Intraturbinal injection of steroid can yield rapid relief of nasal obstruction caused by severe allergic or vasomotor rhinitis, rhinitis medicamentosa, or acutely enlarged nasal polyps. This modality is not meant to replace the traditional means of therapy for these diseases. Despite previous reports of visual loss after intraturbinal steroid, thousands of such injections have been given with no such disastrous complications. The technic should include preliminary topical cocainization of the nasal mucosa, slow injection using a small gauge needle, and steps to allay apprehension and prevent a “needle reaction.” In a retrospective study comparing intraturbinal triamcinolone with intramuscular betamethasone, the intraturbinal steroid was judged much more effective. Side effects reported after intranasal steroid were minor in nature. No visual complications have occurred in this series.

ISSN:0038-4348    

出版商:OVID    

年代:1978

数据来源: OVID

ISSN:0038-4348    

出版商:OVID    

年代:1978

数据来源: OVID

摘要:

Each of the four general classes of laser (gas, solid, liquid, and semiconductor) emits a particular wavelength of light. This beam of light can be focused to a minutely accurate diameter and the depth of penetration can be controlled by the power input. Thus, there is minimal damage to surrounding tissue. A carbon dioxide laser was used to treat congenital hemangioma, verruca vulgaris, and condyloma acuminatum, and to remove tattoos. Of the four types of lesions treated, verruca vulgaris, condyloma acuminatum, and tattoos responded best.

ISSN:0038-4348    

出版商:OVID    

年代:1978

数据来源: OVID

摘要:

In our three-year experience with the use of flutamide for the treatment of carcinoma of the prostate, 20 patients with previously untreated stage D carcinoma of the prostate were enrolled in a 12-week double-blind study. Seven patients received 1.5 gm of flutamide daily, seven patients received 0.75 gm of flutamide daily, and six patients received 1.0 mg of diethylstilbestrol daily. Two patients receiving flutamide did not complete the 12-week study. Six patients receiving flutamide and three patients receiving diethylstilbestrol had objective evidence of improvement. Of the patients receiving flutamide, 50% were alive at one year, and 43% were alive at two years. Three of the original 14 patients started on flutamide are alive at 36, 33, and 24 months. In addition, we continued clinical evaluation of flutamide as an open study, enrolling six other patients (four with stage D and two with stage C carcinoma of the prostate). All except one of these patients had received previous hormonal therapy. At present, four are still being followed up at 13, 15, 20 and 24 months, demonstrating that flutamide can give positive results to some patients whose condition is deteriorating despite diethylstilbestrol therapy.

ISSN:0038-4348    

出版商:OVID    

年代:1978

数据来源: OVID

摘要:

A series of patients with 3,817 cutaneous carcinomas of different types observed in a private practice setting is reported. Preliminary computerized analyses indicate that 88% of these squamous cell and basal cell carcinomas were < 25 mm. Scalpel surgery, curettage and desiccation, or radiation therapy was used for most tumors and an overall cure rate of > 98% was obtained. A pretreatment biopsy allowed for selection of the most appropriate management and authoritative instructions for long-term follow-up visits and prophylaxis.

ISSN:0038-4348    

出版商:OVID    

年代:1978

数据来源: OVID

摘要:

Adenocarcinoma of the bladder is an uncommon malignancy comprising less than 2% of all bladder tumors. Eleven cases of adenocarcinoma of the bladder were seen from 1947 to 1977 at the Ochsner Medical Institutions. Six of the tumors were urachal in origin, and five involved the base and lateral walls of the bladder. Six patients were treated with total cystectomy, four with segmental cystectomy, and one with radiation therapy only. The average survival time for the patients with urachal adenocarcinoma was 2.8 years and for those with vesical adenocarcinoma, 2.4 years. Although segmental cystectomy is recommended by some, the authors recommend radical cystectomy for all patients with adenocarcinoma of the bladder.

ISSN:0038-4348    

出版商:OVID    

年代:1978

数据来源: OVID

摘要:

Four metastatic tumors of the foot, of colonic, renal and humeral origin, are described. They involved three calcanei and two tali. All four patients died within a few months after the appearance of metastasis to the foot. Bony destruction, pain, and swelling can closely resemble the clinical signs and symptoms of osteomyelitis. Diagnostic roentgenograms must be obtained to rule out the possibility of metastatic disease, and biopsies are usually required for accurate diagnosis.

ISSN:0038-4348    

出版商:OVID    

年代:1978

数据来源: OVID