ISSN:0038-4348    

出版商:OVID    

年代:1978

数据来源: OVID

ISSN:0038-4348    

出版商:OVID    

年代:1978

数据来源: OVID

ISSN:0038-4348    

出版商:OVID    

年代:1978

数据来源: OVID

摘要:

Sections from 879 consecutive breast biopsies performed for clinically and grossly benign disease between 1962 and 1966 were reviewed. Twenty-four cases of undiagnosed lobular carcinoma in situ or atypical lobular hyperplasia and six cases of intraductal papillary carcinoma were found. Only one patient later developed invasive carcinoma, an infiltrating lobular carcinoma in the ipsilateral breast, which was diagnosed seven years after the biopsy containing lobular carcinoma in situ. Invasive cancers have not been found in other patients who have a median follow-up period of eight years.

ISSN:0038-4348    

出版商:OVID    

年代:1978

数据来源: OVID

摘要:

Adenocarcinoma of the ampulla of Vater represents about 10% of periampullary neoplasms. This tumor is slow-growing, often amenable to radical surgical resection, and associated with a better prognosis than the other neoplasms which arise in the periampullary area. Correct identification of ampullary carcinoma may be difficult but is essential because of its better prognosis. A review of 31 patients with adenocarcinoma of the ampulla of Vater treated at our institution reveals that the classical history of fluctuating jaundice and the well known findings of a palpable gallbladder and occult blood in the stool may not be present. The treatment of choice for ampullary carcinoma in the absence of hepatic or distant metastases is pancreaticoduodenectomy. Our operative mortality for pancreaticoduodenectomy is 16%, and the five-year survival rate is 32%. The role of palliative procedures, the operative complications, and the survival rates are discussed.

ISSN:0038-4348    

出版商:OVID    

年代:1978

数据来源: OVID

摘要:

The case histories of three women with verrucous carcinoma of the vagina are presented. Verrucous carcinoma, in the female genital tract as elsewhere, is a relentlessly growing, destructive, but generally nonmetastasizing neoplasm of stratified squamous epithelium with a characteristic gross and microscopic appearance. It should be recognized and segregated from the usual type of squamous carcinoma so that appropriate therapy can be administered. Surgical excision is the treatment of choice. Radiotherapy is usually contraindicated. Two of the patients described here were treated by surgery alone with good results. The other received radiation only and died within a year with persistent disease.

ISSN:0038-4348    

出版商:OVID    

年代:1978

数据来源: OVID

ISSN:0038-4348    

出版商:OVID    

年代:1978

数据来源: OVID

摘要:

Although carcinoma of the testicle is a rare lesion, one family physician saw three cases in 18 months. He diagnosed all correctly and referred the patients for treatment immediately. All three patients are living and well. We believe his alertness is worthy of note because, given the rarity of the lesion, a low index of suspicion and delayed diagnosis often occur, with less than desirable results.

ISSN:0038-4348    

出版商:OVID    

年代:1978

数据来源: OVID

摘要:

Two cases of Hodgkin's disease associated with pregnancies are presented. Review of the literature failed to show that pregnancy had any deleterious effect on either the course or survival of patients with Hodgkin's disease; nor did therapeutic abortion alter the survival curves of these patients. There is only one report of Hodgkin's disease metastasizing to the products of conception. Both chemotherapy and irradiation are used to treat Hodgkin's disease, and both are potentially harmful to the growing fetus. Therefore, if therapy can be delayed without detriment to the patient, it should be postponed until after termination of the pregnancy.

ISSN:0038-4348    

出版商:OVID    

年代:1978

数据来源: OVID

摘要:

The pronounced predilection of bronchogenic carcinoma for tuberculous lobes of the lungs is not generally recognized. In this plus 11 other series of patients with coexisting disease, an average of 52% had the neoplasm in a tuberculous lobe. In the present study, tuberculosis was confined to one or two lobes in 24 of 27 patients (89%) with coexisting disease; 21 (88%) of these patients had the neoplasm in a tuberculous lobe. Diagnosis required an average of 1.8 months (one week to 18 months). A low index of suspicion can delay diagnosis of the carcinoma until hilar enlargement, tumor, or metastasis is apparent radiologically. By then, often the tumor has become inoperable. Our data suggest that carcinoma should be suspected in a tuberculous man of cancer age who smokes and who has a lesion which is enlarging, is in an unusual location, or is drug resistant. Cytologic study of sputum, bronchoscopy, and early thoracotomy are advocated.

ISSN:0038-4348    

出版商:OVID    

年代:1978

数据来源: OVID