ISSN:0038-4348    

出版商:OVID    

年代:1983

数据来源: OVID

ISSN:0038-4348    

出版商:OVID    

年代:1983

数据来源: OVID

ISSN:0038-4348    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

We reviewed the records of 100 medical and surgical patients who received cimetidine while hospitalized. Cimetidine use was categorized by FDA criteria asjustified(23%),acceptable(40%), orunjustified(37%); prescribing patterns were similar in medical and surgical patients. Furthermore, intravenous cimetidine was often given when patients were receiving oral feedings, which resulted in unnecessary increases in hospital costs.

ISSN:0038-4348    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

One hundred fifty patients underwent surgery for mitral valve disease between January 1974 and May 1981. There were 98 female and 52 male patients with a mean age of 57 years (≤ 18.6). One hundred forty-six patients were in New York Heart Association functional class III or IV. Pathologic diagnoses included 67% rheumatic (55 calcified), 27% degenerative and fibrotic, 3.3% prosthetic valve malfunctions, and 2.6% acute papillary muscle dysfunction. Atrial biopsy material was normal in 72% (37/51) and Aschoff's bodies were present in 2% (1/51). Preoperative cardiac rhythm was regular sinus in 40%, atrial fibrillation in 59%, and pacemaker-induced in 1%. Valve replacement was performed in 119 patients, commissurotomy in 26, and annuloplasty in five. Left atrial thrombus was removed from 21 patients. Hospital mortality was 10%. The 135 survivors have been followed up for an average of 30.4 months. Of patients who were in regular sinus rhythm preoperatively, 90.7% maintained it postoperatively, and 9.3% converted to atrial fibrillation. Of patients in atrial fibrillation preoperatively, 33.8% converted to regular sinus rhythm postoperatively and 66.2% remained in atrial fibrillation. These data indicate that rheumatic mitral valve disease is still the most common finding in patients coming to surgery, followed by degenerative and fibrotic mitral valve disease. Acute papillary music dysfunction is uncommon. The chance of preserving preoperative regular sinus rhythm postoperatively is excellent (90.7%), and a 33% conversion rate of preoperative atrial fibrillation to postoperative regular sinus rhythm is encouraging.

ISSN:0038-4348    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

One hundred forty-one subjects with osteoarthritis completed this double-blind, multicenter, crossover trial comparing four nonsteroidal anti-inflammatory (NSAI) agents after single-blind aspirin stabilization. Preferences of both patients and physicians showed the following rank order from most to least preferable; tolmetin sodium, naproxen, ibuprofen, fenoprofen calcium. By all but three of more than 20 measures of efficacy, tolmetin sodium and naproxen were the more effective pair and fenoprofen calcium and ibuprofen the less effective pair of the four. Eight of nine measures of tolerability suggested the following rank order from best to worst tolerated: ibuprofen, naproxen, tolmetin sodium, fenoprofen calcium, aspirin. Few differences among the newer NSAI agents compared in this study achieved statistical significance. Nevertheless, the tolerability-efficacy relationships that emerge from studies of this type can help to define rational approaches to the use of these drugs in rheumatic diseases.

ISSN:0038-4348    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

This paper describes five patients with mitral valve prolapse (MVP) and intracranial aneurysms. Patients with MVP frequently have evidence of a more generalized disorder of connective tissue. An association of intracranial aneurysms and MVP could be related to mesodermal disturbances involving collagen and elastic tissue in the vasculature. Further study is needed to confirm this association and to elucidate the nature of any underlying connective tissue defect.

ISSN:0038-4348    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

The effect of erythromycin sterate (ES) on serum theophylline concentration (STC) was studied in 15 male adult subjects taking maintenance oral theophylline for clinically stable chronic obstructive lung disease. Steady-state trough STCs were measured before and after two-and seven-day courses of ES, 500 mg every six hours. For the group as a whole, there was no significant increase in trough STC after either course of ES therapy, but five of 15 subjects exhibited increases in trough STC ranging from 4 to 8 μg/ml (mean increase of 5.4 μg/ml (mean increase of 5.4 μg/ml) within 48 to 96 hours of beginning ES therapy. Clinical theophylline toxicity developed in one of these subjects. Based on this study and others in the literature, erythromycin preparations may induce a clinically significant and potentially toxic increase in STC in a variable proportion of patients taking maintenance theophylline therapy.

ISSN:0038-4348    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

In contrast to the generally accepted concept, I have classified congenital subglottic stenosis in a different way. During the first months of life, the abnormality may be recognized by its frequent association with acute respiratory infections, providing the opportunity to recognize it once the infection has been controlled. I emphasize the role of the radiologic examination of the larynx for diagnosis and follow-up of this disorder and its different evolution from that of pure subglottic laryngitis. A comparison with subglottic laryngitis and laryngotracheobronchitis emphasizes the seriousness of this retardation in the normal development of the larynx.

ISSN:0038-4348    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

Unmodified, commercially available, gray-scale ultrasound equipment has been used in a small community hospital to image various small organs. Seven examples are presented to emphasize the versatility of such equipment for obtaining clinically useful information.

ISSN:0038-4348    

出版商:OVID    

年代:1983

数据来源: OVID