摘要:

Comment: Fluid loading before aortic unclamping during abdominal aortic aneurysm surgery is the usual practice in most situations. Measurement of the efficacy of this can be via several modalities–blood pressure, venous pressure, pulmonary capillary wedge pressure, or right ventricular end-diastolic volume. This study suggests that right ventricular end-diastolic volume

ISSN:0039-6206    

出版商:OVID    

年代:1994

数据来源: OVID

摘要:

Comment: There certainly is little room for argument with this article. Universal agreement exists, which asserts that propofol is a much better drug than thiopental for laryngeal mask insertion. This article is included to emphasize the point

ISSN:0039-6206    

出版商:OVID    

年代:1994

数据来源: OVID

摘要:

Comment: There has been considerable controversy for years concerning the “best” solution for resuscitation of hemorrhagic shock victims. Colloid versus crystalloid and iso-osmolar vs. hyperosmolar have had advocates and their day in the sun. Dextrans (of all molecular weights) have never appealed to me as much as crystalloid solutions. The major issues are platelet function inhibition, clearance of the foreign substance, and limitations of dose. For now, I will stay with crystalloid solutions. This article tends to agree with my use.

ISSN:0039-6206    

出版商:OVID    

年代:1994

数据来源: OVID

摘要:

Comment: Calcium signal transduction in endothelial cells in response to various mediators is a major pathway in determining vasoactive physiologic and pharmacologic responses. Because halothane and isoflurane have very different blood pressure effects, it is logical to hypothesize that they may have different effects on the peripheral vascular endothelium. This study demonstrates that halothane interferes with the calcium pathway stimulated by bradykinin but isoflurane does not. The actual mechanism for this interference was not determined. Whether this interference actually accounts for the different peripheral vascular effects of the inhalation anesthetics will require further investigation.

ISSN:0039-6206    

出版商:OVID    

年代:1994

数据来源: OVID

摘要:

Comment: This investigation is the first in vivo study of transdermal iontophoresis on fentanyl and sufentanil pharmacokinetics coupled with acute nociceptive properties. However, because iontophoresis was applied for only 1 hr, steady-state plasma levels were not attained, making it impossible to compare the results with transdermal fentanyl and sufentanil delivery systems not dependent on iontophoresis. Also, there is no mention of the number of animals included in the study, the mode of evaluation, and the number of blood samples collected. Therefore, one should be cautious in extrapolating these results to humans

ISSN:0039-6206    

出版商:OVID    

年代:1994

数据来源: OVID

ISSN:0039-6206    

出版商:OVID    

年代:1994

数据来源: OVID

摘要:

Comment: The interesting aspect of this article for me was not the results, which displayed no differences in the two groups, but the statement of the mechanism for how a difference might occur. Could we extrapolate this thought process to state that drinking a carbonated cola drink is painful? I doubt it

ISSN:0039-6206    

出版商:OVID    

年代:1994

数据来源: OVID

ISSN:0039-6206    

出版商:OVID    

年代:1994

数据来源: OVID

ISSN:0039-6206    

出版商:OVID    

年代:1994

数据来源: OVID

ISSN:0039-6206    

出版商:OVID    

年代:1994

数据来源: OVID