摘要:

AbstractThe hitherto isolated and identified cembrane derivatives from alcyonarians of the Gulf of Elat (Red Sea) are briefly reviewed, including the thus far unreported isolation of nephtenol and 16‐deoxysarcophine from several soft‐corals. The structure of a new sinulariolide derivative, 11‐episinulariolide acetate, isolated together with 11‐dehydrosinulariolide, from two (out of seven tested) sinularia species is illu

ISSN:0021-2148    

DOI:10.1002/ijch.197700002

出版商:WILEY‐VCH Verlag    

年代:1977

数据来源: WILEY

摘要:

AbstractOxidation of 1,2,3,4‐tetrahydro‐7‐hydroxy‐6‐methoxy‐3‐(4,5‐dimethoxy‐2‐vinylphenyl)‐2‐methylisoquinoline (10), derived from the corresponding berbine methiodide (8), with lead tetraacetate, followed by acidic treatments, gave 5,6‐dihydro‐8‐hydroxy‐2,3,9‐trimethoxy‐5‐methylbenzo[c]phenenthridine (20). By a similar procedure, 1,2,3,4‐tetrahydro‐7‐hydroxy‐6‐methoxy‐3‐(4,5‐methylenedioxy‐2‐vinylphenyl)‐2‐methylisoquinoline (11) was converted tocis‐8‐acetoxy‐4b,5,6,10b‐tetrahydro‐9‐methoxy‐5‐methyl‐2,3‐methylenedioxybenzo[c]phenanthridine (17), whose hydrolysis with hydrochlo

ISSN:0021-2148    

DOI:10.1002/ijch.197700003

出版商:WILEY‐VCH Verlag    

年代:1977

数据来源: WILEY

摘要:

AbstractChanges in human metabolism caused by physical or mental stress were examined by monitoring the rate of excretion of metabolites via the urine. Gas liquid chromatography and mass spectra analysis of urine revealed differences in the rate of metabolite excretion between mental stressed and unstressed persons: Emotional stress causes an increase in the DHEA excretion for a factor up to twenty. Physical stress does not change the steroid pattern, but is manifested in respect to a much greater increase in excretion of citric acid and isocitric acid and decrease in excretion of amino acid conjugates in untrained persons as compared to trained athletes.

ISSN:0021-2148    

DOI:10.1002/ijch.197700004

出版商:WILEY‐VCH Verlag    

年代:1977

数据来源: WILEY

摘要:

AbstractTwo compounds, tricin and a related new flavolignan have been isolated fromAegilops ovataL. dispersal units. Evidence leading to assignment of structure of this new compound is presented together with1H and13C‐NMR chemical shifts of related model compounds. These phenolics found together in the same plant species with a previously discovered lignan possessing activity as a germination inhibitor, raise the possibility of a new biogenetic lin

ISSN:0021-2148    

DOI:10.1002/ijch.197700005

出版商:WILEY‐VCH Verlag    

年代:1977

数据来源: WILEY

摘要:

AbstractFurther examination of the hexane extract of the root bark ofSimarouba amara(Simaroubaceae) has led to the isolation of two side chain oxygenated Δ7‐tirucallol‐type triterpenes in addition to the already reported compounds4and5. One has been found to be identical with the known melianone8and the second is a new compound and has been shown to be 21,20‐anhydromelianone11. The13C‐NMR spectra of nine Δ7‐tirucallol derivatives have been analysed and the data obtained have been applied to the confirmation of the structure of the new

ISSN:0021-2148    

DOI:10.1002/ijch.197700006

出版商:WILEY‐VCH Verlag    

年代:1977

数据来源: WILEY

摘要:

AbstractReciprocal crossbreeding betweenWithania somniferachemotype III (Israel) and chemotype Indian I (Delhi) were performed. The F1offspring of this cross was characterized by significant changes in the main steroidal lactone constituents of the parent plants. From the withaferin A (9) and the withanone (2) both present as major constituents in the parent Indian I, the former had disappeared in the hybrid and was replaced by withanolide D (10), whereas the latter was still present, though in about one third of the original quantity. It was accompanied by 17‐deoxy‐20‐hydroxy withanone (2) and by withanolide T (1); the enzymatic system leading to hydroxylation at C20(20αF‐OH) has a dominant character. Two new withanolides have been isolated from this F1offspring, namely withanolide T (1) (20αF‐hydroxy withanone) and withanolide U (5) (4β‐hydroxy‐withanolide G). The structures assigned to these two new compounds are based on spectral evidence (NMR, IR and UV) and analysis of their fragmentation under

ISSN:0021-2148    

DOI:10.1002/ijch.197700007

出版商:WILEY‐VCH Verlag    

年代:1977

数据来源: WILEY

摘要:

AbstractCondensation of 3‐ketobisnorcholenal (1) with malononitrile could be directed selectively to the aldehyde group to afford dicyanomethylene ketone3. Ketalization of3with ethylene glycol followed by alkaline hydrolysis gave the aldehydo dioxolane5, which served as starting material for the syntheses of 1,3‐propanediol derivatives7and10and their respective dicarbamates9an

ISSN:0021-2148    

DOI:10.1002/ijch.197700008

出版商:WILEY‐VCH Verlag    

年代:1977

数据来源: WILEY

摘要:

AbstractWarburganal and muzigadial are two new sesquiterpenes isolated from a medicinal plant. They are two of the strongest antifeedants against the monophagous African army worm; in addition they possess potent molluscicidal activity and other antibiotic properties. A general account is given on these aspects as well as the spectral data leading to determination of their structures.

ISSN:0021-2148    

DOI:10.1002/ijch.197700009

出版商:WILEY‐VCH Verlag    

年代:1977

数据来源: WILEY

摘要:

AbstractCurrent notions concerning the biogenesis of this large group of naturally occurring substances are discussed with emphasis on stereochemical aspects.

ISSN:0021-2148    

DOI:10.1002/ijch.197700010

出版商:WILEY‐VCH Verlag    

年代:1977

数据来源: WILEY

摘要:

AbstractWhile the flavonoids are biosynthetically and constitutionally a homogeneous group of compounds, the neoflavonoids, as presently defined, may be biosynthetically and are constitutionally a heterogeneous group. Biogenetic considerations which lead to these conclusions and reviews on occurrence, structural elucidation and synthesis are presented for 1,3‐diarylpropanes and flavans (flavonoids), as well as for cinnamylphenols and 2‐aryl‐3‐methylbenzofurans (neoflavonoids), with the purpose of providing addenda to the 1975 monograph,The Flavonoids, edited by Harborne, Mabry and Mabry for Chapman and Hall,

ISSN:0021-2148    

DOI:10.1002/ijch.197700011

出版商:WILEY‐VCH Verlag    

年代:1977

数据来源: WILEY