摘要:

A reversed-phase high-performance liquid chromatographic (HPLC) procedure using ultra-violet (UV) detection for the analysis of edetate disodium (EDTA) via complexation with iron, in an ophthalmic cleanser, is reported. The method is selective, accurate, and reproducible. The peak area versus EDTA concentration is linear over the range of 50–150% of its label claim of 0.30 mg/mL, with a detection limit of 200 ng/mL. The mean absolute recovery of EDTA, using the described method, is 102.7 ± 0.4% (mean ± SD, n = 10).

ISSN:1082-6076    

DOI:10.1080/10826079608007198

出版商:Taylor & Francis Group    

年代:1996

数据来源: Taylor

ISSN:1082-6076    

DOI:10.1080/10826079608007199

出版商:Taylor & Francis Group    

年代:1996

数据来源: Taylor

ISSN:1082-6076    

DOI:10.1080/10826079608007200

出版商:Taylor & Francis Group    

年代:1996

数据来源: Taylor