摘要:

Seven healthy older volunteers participated in a 33-day study consisting of three sample collection periods, a 10-day control, and two 10-day experimental periods. Subjects consumed their usual self-selected diets throughout and a daily wheat bran supplement (30 g) during the two experimental periods. Food intake was recorded daily by subjects and accuracy and completeness checked daily by personal interview. Apparent calcium absorption decreased significantly from 22.1 +/−5.6% (mean +/−SD) during the control to 8.6 +/−5.2% during the second bran period. The wheat bran supplement significantly increased wet and dry stool weights but had no effect on stool moisture or defecation frequency. Gastrointestinal transit time of a dose of chromium decreased significantly, from 75 +/−33 to 54 +/−19 hr; of a dose of polyethylene glycol insignificantly, from 98 +/−59 to 69 +/−46 hr. Mean recovery of 21 doses of chromium of 98.7 +/−5.0% verified that stool collection was complete. The results suggest that the ability of wheat bran to regulate bowel function in the apparently healthy older adult may be accompanied by increased fecal calcium losses similar to what has been reported for younger adults.

ISSN:0731-5724    

DOI:10.1080/07315724.1987.10720182

出版商:Routledge    

年代:1987

数据来源: Taylor

摘要:

Middle-aged and elderly females aged between 51 and 86 years volunteered for this study. In June and July, 147 females were studied; data collected through interview included general socioeconomic information, health history, use of medication, and a 7-day food intake. During the same 7-day period, physical activity level was measured for each person by use of a pedometer. On the 8th day, anthropometric measurements were conducted and fasting blood was analyzed for certain hormones and related metabolites. In the following January and February, the same group was surveyed again and the same measurements were repeated. Of the initial 147 subjects, 130 persons completed the winter survey. A comparison of the summer and winter data indicated some significant differences: mean body weight increased in winter from 70.4 +/−12.7 to 71.1 +/−13.5 kg (p less than or equal to 0.05); energy intake was raised from 1450 +/−384 to 1549 +/−372 kcal (p less than or equal to 0.01); physical activity decreased from 10.9 +/−8.2 to 8.5 +/−5.4 miles/week (p less than or equal to 0.01); and serum free thyroxine (T4) fell from 1.72 +/−0.27 to 1.64 +/−0.27 ng/dl. These results together with other data suggest that more attention should be addressed to seasonal fluctuations involved in body weight maintenance.

ISSN:0731-5724    

DOI:10.1080/07315724.1987.10720183

出版商:Routledge    

年代:1987

数据来源: Taylor

摘要:

There is some indication that change of seasons, from summer to winter, alters certain hematological parameters that could be indicative of hemodilution and hemoconcentration. To investigate this further, we studied adult females (n = 130) aged between 51 and 86 years during summer and winter to evaluate any seasonal variations in selected hematological and related parameters. Data included a 7-day food intake, anthropometry, and hematological analysis of fasting blood. Erythrocyte and leukocyte counts, hematocrit (HCT), and hemoglobin (Hb) increased significantly in the winter compared to summer (p less than 0.01), but intakes of folacin, vitamin B12, and iron did not change. No effects of age or race were observed on these changes. Significantly elevated leukocyte counts (p less than 0.002), HCT (p less than 0.03), and Hb (p less than 0.007) were observed among smokers; however, smoking had no effect on the seasonal changes in hematological values. The increase in HCT was greater for persons using diuretics than those who were not on diuretics (p less than 0.05). The seasonal changes in erythrocyte counts (p less than 0.01), HCT (p less than 0.01), and Hb (p less than 0.05) were significantly correlated to the changes in plasma protein concentration among the subjects, suggesting hemoconcentration in winter and hemodilution in summer to some extent. The present study suggests that seasonal variation may occur in hematological parameters and that these factors should be taken into consideration when evaluating survey data.

ISSN:0731-5724    

DOI:10.1080/07315724.1987.10720184

出版商:Routledge    

年代:1987

数据来源: Taylor

摘要:

A sex difference in nitrogen balance was investigated in 40 adults, 21 men and 19 women, undergoing chemoradiotherapy and marrow transplantation for leukemia and receiving total parenteral nutrition. Twenty-four hour collections of urine and mixed urine-stool were analyzed for total nitrogen daily through day 14 posttransplant. Nitrogen balance, corrected for changes in blood urea nitrogen, decreased significantly over time (p less than 0.005) in both men and women, but men experienced a greater negative nitrogen balance during the time period (p less than 0.001). Mean daily nitrogen balance in men was -6.0 g for week 1 and -9.2 g for week 2, corresponding to -3.3 g and -5.6 g in women for week 1 (p less than 0.005) and 2 (p less than 0.01), respectively. The differences remained after controlling for stress level and adjusting for total calorie intakes. There were no differences in age, disease status, or nitrogen intakes per kg ideal body weight, and no effects on nitrogen balance by arm muscle area at admission, cyclosporine use, or the branched-chain amino acid content of the parenteral solution. The average rise in 3-methylhistidine excretion was 23% in men and 11% in women. These results suggest higher per kg nutrient needs in males during stress and may indicate differing metabolic responses to stress. The possibility of gender differences should be considered in research evaluating nitrogen metabolism during severe stress.

ISSN:0731-5724    

DOI:10.1080/07315724.1987.10720185

出版商:Routledge    

年代:1987

数据来源: Taylor

摘要:

Resting energy expenditure (REE) was measured in 100 consecutive total parenteral nutrition (TPN) patients. Only forty-eight percent of the measured REEs were within 90-110% of the predicted Harris-Benedict values. A literature review revealed 191 published guidelines for non-protein caloric requirements of hospitalized TPN patients. These guidelines were appropriately matched and applied to the 100 individual TPN patients. The relationship between the recommended caloric supply and measured caloric expenditure was minimal. The recommendations exceeded measured REE by an average of 1076 +/−660 kcal/day. These published guidelines were substantially above and below caloric requirements based on measured REE for both fat maintained (130% REE) and fat depleted (150% REE) patients. Following published guidelines rather than standards based on measured REE results in the administration of 6947 excess liters of TPN per year. Improvement in the precision of TPN caloric prescription can be accomplished by using measured REE as a reference base. When published guidelines were compared to prescriptions based on measured REE it was found that published guidelines were inaccurate both overall and individually and a substantial cost savings justifies actual measurement of energy needs.

ISSN:0731-5724    

DOI:10.1080/07315724.1987.10720186

出版商:Routledge    

年代:1987

数据来源: Taylor

摘要:

Clostridium difficile diarrhea (CDD) is a frequent cause of hospital-associated infectious diarrhea and a common reason for nutritional consultation. Limited data are available on fecal nitrogen losses during infectious diarrhea in adults. Eleven patients with acute CDD were studied for stool volume and fecal nitrogen. The mean stool output was 630 +/−110 g/day and fecal nitrogen 2.5 +/−0.3 g per 24 hour period (mean +/−SEM). Fecal nitrogen loss was increased from the predicted 12.0 mg/kg BW/day to 38.0 +/−5.9 mg/kg BW/day. Fecal nitrogen loss in CDD can be an important source of nitrogen loss and should be measured in nitrogen balance studies in such patients.

ISSN:0731-5724    

DOI:10.1080/07315724.1987.10720187

出版商:Routledge    

年代:1987

数据来源: Taylor

摘要:

In this review, we first summarized the evidence from animals and man for and against a role for dietary sodium in the genesis and treatment of hypertension. The evidence for a role for dietary sodium in the genesis of hypertension is strongest in those subjects with impaired ability to excrete sodium due to organic renal disease or mineralocorticoid excess. Here restriction of dietary sodium promptly lowers arterial pressure. Its role in the genesis of essential hypertension is still controversial. Nevertheless, it appears that some patients with mild to moderate essential hypertension respond to moderate sodium restriction with a modest fall in blood pressure. This restriction also seems to reduce the amount of antihypertensive medication needed to keep blood pressure under control. We next considered the mechanism of the pressure response to dietary sodium chloride, concentrating upon the increase in extracellular fluid volume, potassium depletion, and increased plasma levels of prohypertensive sodium pump inhibitor and antihypertensive atrial natriuretic factor. We next summarized the evidence for a primary role for dietary potassium in the genesis of hypertension and pointed out that certain subsets of subjects with a high incidence of hypertension also have a lower dietary potassium intake. Some investigators find that dietary potassium supplementation lowers blood pressure in established hypertension. This may result from natriuresis and from vasodilation subsequent to stimulation of Na+, K+-ATPase in vascular smooth muscle and adrenergic nerve terminals. We then considered practical aspects of dietary sodium restriction and dietary potassium supplementation in the therapy for established hypertension. The review concludes with comments on their possible roles in the prevention of hypertension.

ISSN:0731-5724    

DOI:10.1080/07315724.1987.10720188

出版商:Routledge    

年代:1987

数据来源: Taylor

摘要:

The relation of alcohol use to calorie intake and adiposity was studied in 155 non-smoking, overweight men. Alcohol use and calorie intake were assessed by 7-day dietary record, and body composition was determined by hydrostatic weighing. Increased intake of food calories (i.e., non-ethanol calories only) on alcohol-drinking days was compensated for by decreased food consumption on non-drinking days of the week. Added alcohol calories were not offset during the week and resulted in a surplus intake of over 4,000 kcal/wk for men in the highest drinking group. Although alcohol calories were“added”to food intake, alcohol use was unrelated to level of adiposity. This finding was not accounted for by concomitant differences in exercise status. Basal metabolic rate, however, was elevated in men imbibing one or more“drinks”per day (as compared to abstainers and light-drinkers). Increased basal energy expenditure may have partially offset the alcohol calories of men at lower levels of alcohol intake, but it did not substantially offset the large calorie surplus seen at higher levels of consumption. Our results support recent speculation that alcohol consumption may not be as“fattening”as traditionally believed.

ISSN:0731-5724    

DOI:10.1080/07315724.1987.10720189

出版商:Routledge    

年代:1987

数据来源: Taylor

摘要:

The morbidly obese who undergo elective gastric partitioning surgery serve as models of surgical stress and subsequent severe protein calorie restriction. The short and long term effects of gastric partitioning surgery on circulating proteins and the specific micronutrients carried by the proteins were studied in 22 such patients (ages 23-56 years). Serum micronutrient values paralleled the levels of their carrier proteins. Mean concentrations of both short and long turnover proteins decreased significantly in the early postoperative period, whereas the acute phase reactant ceruloplasmin reached preoperative levels by the seventh postoperative day. Transthyretin and retinol binding protein remained depressed with long term reductions in protein and calorie intake, whereas ceruloplasmin and transferrin were somewhat less sensitive to prolonged protein-calorie restriction. Mean serum albumin, after an initial postoperative fall, rose to the baseline level by 1 month after surgery. Serum albumin levels remained within the normal range despite low protein and calorie intakes.

ISSN:0731-5724    

DOI:10.1080/07315724.1987.10720190

出版商:Routledge    

年代:1987

数据来源: Taylor

ISSN:0731-5724    

DOI:10.1080/07315724.1987.10738107

出版商:Routledge    

年代:1987

数据来源: Taylor