摘要:

AbstractAs a possible alternative to spectral analysis of biological processes the method of thresholding the recorded function is reconsidered. The frequencies of the section length for a finite set of levels form the frequency surface which is the starting point for inference and reasoning. The paper presents ideas and examples to stimulate the development and use of a suitable electronic equipment.

ISSN:0323-3847    

DOI:10.1002/bimj.4710260302

出版商:WILEY‐VCH Verlag    

年代:1984

数据来源: WILEY

ISSN:0323-3847    

DOI:10.1002/bimj.4710260304

出版商:WILEY‐VCH Verlag    

年代:1984

数据来源: WILEY

摘要:

AbstractWe present two truncated proportional hazards tests. The first, which is applicable to those cases in which the time of action of an agent or treatment is known, was studied in two forms: One uses expected Fisher information and the other observed Fisher information. In this case the expected information statistic,C1(a0), had properties superior to the observed information statistic and is recommended. The use of theX2distribution with one degree of freedom for percentiles appears to be satisfactory. When the time of action is unknown, a statistic based on the maximum of theC1(a) statistics is used. A simulation study gives empirical percentiles for the MaxC1(a) statistic which agree with those given in a study by Muenz, Green and Byar (1977).

ISSN:0323-3847    

DOI:10.1002/bimj.4710260305

出版商:WILEY‐VCH Verlag    

年代:1984

数据来源: WILEY

摘要:

AbstractFor the modely=β0+ β1x +e(model I of linear regression) in the literature confidence estimators of an unknown positionx0are given at which either the expectation ofyis given (see FIELLER, 1944; FINNEY, 1952), or realizations ofyare given (see GRAYBILL, 1961). These confidence regions with level 1—α need not be intervals. The occurrence of interval shape is a random event. Its probability is equal to the power of thettest for the examination of the hypothesisH: β1= 0. The papers mentioned above claim to provide confidence intervals with level 1 − α. But because of the restriction of (1 —α)—confidence regions to intervals the true confidence probability is the conditional probabilityWc:Wc=P(the confidence region coversx0| the region has interval shape). Here this conditional probability is shown to be less than 1 —α. Evidence on the possible deviations from 1 —α has been obta

ISSN:0323-3847    

DOI:10.1002/bimj.4710260306

出版商:WILEY‐VCH Verlag    

年代:1984

数据来源: WILEY

ISSN:0323-3847    

DOI:10.1002/bimj.4710260307

出版商:WILEY‐VCH Verlag    

年代:1984

数据来源: WILEY

摘要:

AbstractThe paper outlines a method of analysis of intricically non‐linear regression functions. The nonlinear model is first approximated by a cubic spline function. Thereafter, the standard methods of analysis in linear models are applied to obtain estimates and test statistic

ISSN:0323-3847    

DOI:10.1002/bimj.4710260308

出版商:WILEY‐VCH Verlag    

年代:1984

数据来源: WILEY

摘要:

AbstractThe covariance matrix of the least‐squares‐estimator for the coefficients of the mixed model of linear regression is deduced. This serves as a base to work out procedures experimental design for point and confidence estimations of the regression coefficients and the regression function. So it was shown, that the C‐, A‐, D‐ and G‐optimal designs in the mixed model are the same as in model I. Further an assertion for sample size determination is proved especially for point estimation of the regressi

ISSN:0323-3847    

DOI:10.1002/bimj.4710260309

出版商:WILEY‐VCH Verlag    

年代:1984

数据来源: WILEY

ISSN:0323-3847    

DOI:10.1002/bimj.4710260310

出版商:WILEY‐VCH Verlag    

年代:1984

数据来源: WILEY

摘要:

AbstractWe find the general form of the proper Gaussian Markov chains of second order and give an example for them. Comparing with the Gaussian Markov processes they can be used as an improved growth model.

ISSN:0323-3847    

DOI:10.1002/bimj.4710260311

出版商:WILEY‐VCH Verlag    

年代:1984

数据来源: WILEY

摘要:

AbstractA reasonable and computationally straightforward method is proposed for use to analyze clustered samples in medical research. Results are illustrated with examples in ophthalmology and otolaryngology.

ISSN:0323-3847    

DOI:10.1002/bimj.4710260312

出版商:WILEY‐VCH Verlag    

年代:1984

数据来源: WILEY