摘要:

AbstractIn this paper we propose a class of distribution‐free tests for the treatments versus control setting using the partially sequential sampling technique. Expressions for the asymptotic distributions and power for the tests are provided and criteria for adapting a particular test to have asymptotic power restrictions against alternatives of interest are discussed. Comparative results of a Monte Carlo power study are also presente

ISSN:0323-3847    

DOI:10.1002/bimj.4710370302

出版商:WILEY‐VCH Verlag    

年代:1995

数据来源: WILEY

ISSN:0323-3847    

DOI:10.1002/bimj.4710370303

出版商:WILEY‐VCH Verlag    

年代:1995

数据来源: WILEY

摘要:

AbstractWhen conducting a statistical analysis of data from a designed experiment, an investigator is often interested in confidence intervals for contrasts of the fixed effects. If the analysis involves a mixed linear model, exact confidence intervals for contrasts of the fixed effects are not always available. In such cases, confidence intervals with approximate coverage probabilities must be used.As will be shown, this problem may be generalized to that of constructing a confidence interval for the parameter μ, whereXis a normal random variable with mean μ and variance ∑ Qg=1aqθq, wherea1…,aQare known constants,Uq= nqS 2q/θqis a chi‐squared random variable withnqdegrees of freedom, for eachq= 1,…,Q, andX,U1,…,UQare mutually independent. In this paper, we consider the case

ISSN:0323-3847    

DOI:10.1002/bimj.4710370304

出版商:WILEY‐VCH Verlag    

年代:1995

数据来源: WILEY

ISSN:0323-3847    

DOI:10.1002/bimj.4710370305

出版商:WILEY‐VCH Verlag    

年代:1995

数据来源: WILEY

摘要:

AbstractAssuming that the independent variables (factors) are quantitative, there exist besides the coding schemes generally used for the multivariate analysis of variance (dummy‐coded or effect‐coded design matrices) the so‐called polynomial models. The advantage of these polynomial models are the full rank design matrices, which allow a more comprehensible analysis, i.e. the unambiguous interpretation of tested hypotheses and simultaneous confidence inte

ISSN:0323-3847    

DOI:10.1002/bimj.4710370306

出版商:WILEY‐VCH Verlag    

年代:1995

数据来源: WILEY

摘要:

AbstractAssuming some general models for the HIV epidemic, in this paper I derive the HIV incubation distributions under AZT treatment. It is shown that under some conditions, these probability distributions are mixtures of some generalized Gamma distributions and products of generalized Gamma distributions.

ISSN:0323-3847    

DOI:10.1002/bimj.4710370307

出版商:WILEY‐VCH Verlag    

年代:1995

数据来源: WILEY

摘要:

AbstractThis paper presents an identifiability theorem in the theory of dependent competing risks and it applies the result by examining the effect of removing cancer from the United States population when cancer is correlated with the other causes of death. The paper shows how dependence can be modeled with copula functions and it shows that calculating the survival probabilities after cancer is removed is equivalent to solving a system of nonlinear differential equations.

ISSN:0323-3847    

DOI:10.1002/bimj.4710370308

出版商:WILEY‐VCH Verlag    

年代:1995

数据来源: WILEY

摘要:

AbstractIn this article, the spatial statistic known as theKfunction is adapted for temporal processes and patterns. The (optimal)K‐function estimator is used in a testing procedure to determine whether behavior patterns of exposed rats versus control rats are different. Specifically, the temporal analogue to theKfunction is given and an approximately optimal estimator is developed. Next, a testing procedure, to determine whether a group of point patterns is generated from complete temporal randomness, is given. Finally, a testing procedure, to compare pairwise two groups of point patterns to each other, is given. The testing procedures are illustrated with rat‐behavior data from both a control‐control experiment as well as an exposed‐control experiment, where in the latter case a difference in behavior is known t

ISSN:0323-3847    

DOI:10.1002/bimj.4710370309

出版商:WILEY‐VCH Verlag    

年代:1995

数据来源: WILEY

ISSN:0323-3847    

DOI:10.1002/bimj.4710370310

出版商:WILEY‐VCH Verlag    

年代:1995

数据来源: WILEY

摘要:

AbstractThe interval estimation of the ratio of two binomial proportions based on the score statistic is superior over other methods. Iterative algorithms for calculating the approximate confidence interval have been provided by, e.g., KOOPMAN (1984,Biometrics40:513–517) and GART and NAM (1988a,Biometrics44:323–338). This note presents the analytical solutions for upper and lower confidence limits in a closed form and gives examples for numerical illustration. The non‐iterative method is generally more desirable than the iterative m

ISSN:0323-3847    

DOI:10.1002/bimj.4710370311

出版商:WILEY‐VCH Verlag    

年代:1995

数据来源: WILEY