ISSN:1784-3286    

DOI:10.1080/17843286.1988.11717940

出版商:Taylor&Francis    

年代:1988

数据来源: Taylor

摘要:

SummaryBetween 1980 and 1985, 11 children (8 boys, 3 girls aged between 18 months and 16 years) with poor prognosis ALL (Acute Lymphoblastic Leukaemia) were treated with ablative therapy and allogeneic bone marrow transplantation. Six patients (55 %) are alive at the time of evaluation , one died in aplasia, two died of interstitial pneumonia and two died of bone marrow relapse.The median time to recover a neutrophil count of 0.5 x 109/1 was 19 days. The total number of lymphocytes reached normal values after 6 months. The percentage of OKT3 cells (mature T lymphocytes) was slightly depressed during the first 3 months. For at least 9 months, the number of OKT4 (helper lymphocytes) was low with a normal number of OKT8 (suppressor lymphocytes) resulting in an OKT4/OKT8 inverted ratio.As far as B lymphocytes function was concerned, there was a moderate decrease of the immunoglobulin levels. Normal values were obtained after 3 months for IgG, 6 months for IgA and IgM.All the immunological parameters tested returned to normal within one year after the bone marrow transplantation.

ISSN:1784-3286    

DOI:10.1080/17843286.1988.11717941

出版商:Taylor&Francis    

年代:1988

数据来源: Taylor

摘要:

SummaryDuring 8 months. From December 1986 unlil until July 1987. 200 clinical isolates of aminogly coside-resistani bacteria were tested for their production of aminoglycoside-modilying enzymes by means of a stepwise determination scheme, previously published.Enzymes, capable of inactivation of even the most stable aminoglycoside, were almost daily detectable and were closely, associated with nosocomial strains and nosocomial inlections.A higher restriction in antibiotic prescription is urgently required.

ISSN:1784-3286    

DOI:10.1080/17843286.1988.11717942

出版商:Taylor&Francis    

年代:1988

数据来源: Taylor

摘要:

SummaryA comprehensive survey allowed to describe the different trends in the treatment modalities of hyperthyroidism with radioiodine applied in Belgium in 1985. Ii whs found that the mean dose admiuistred was moderate (whether a standard dose or a ealeulaled one was used) and that the aim was to avoid the advent of late hypothyroidism. Not one eenter had chosen to use ablative doses. Antithyroid drugs were extensively used a adjunctive therapy. mainly altei radioiodine administration. An age limit was set at 40 years in 90 of the belgian centers. It is discussed that these modalities are mostly based on theoretical considerations and that the modalities of the treatment of hyperthyroidism with radioiodine should perhaps be reassessed.

ISSN:1784-3286    

DOI:10.1080/17843286.1988.11717943

出版商:Taylor&Francis    

年代:1988

数据来源: Taylor

摘要:

SummaryLeplospirosis is an million caused by a spirochete called Leptospira, frequently found in water and mud. A cosmopolitan zoonosis. it particularty affects rats. pigs. Cattle and dogs and is directly transmissible of man. although it is most frequently through indirect transmission. following contact with water contaminated by the urine infected animals, dial man coniracts the disease.The large majority of human clinieal forms is anieterie with or without symptoms of meningitis: in Belgium, a whole year can go by diagnosis being made or cases being deelared.We report 5 cases of the most serious form of the illness. namely a hepato-nephritis called“Weils disease”, which can be fatal.Discussion also emphasizes on the seasonal nature of the infection and the occupations most at risk and covers the improved diagnosis through the ELISA technique of an infection whcih often requires the patient to be admitted to intensive care.

ISSN:1784-3286    

DOI:10.1080/17843286.1988.11717944

出版商:Taylor&Francis    

年代:1988

数据来源: Taylor

摘要:

SummaryThe potential role of magnetic resonance imaging (MRI) as an unique noninvasive imaging modality in cardiovascular medicine is reviewed. The spatial resolution and anatomic detail of MRI rival or surpass those of other currently available imaging methods. MRI is well suited for the delineation of cardiovascular anatomy of the normal and abnormal heart and large vessels.Local variations in the relaxation parameters T1and T2providing the basis for the contrast of MR images, can be used to differentiate accurately normal and pathologic (e.g. ischemic) myocardial tissue. MRI also appears to be one of the most powerful noninvasive methods to quantify blood flow in vivo.Recent advances in MR technology have made it possible to increase the scope of spectroscopy to the assessment of the human cardiovascular metabolism and function in vivo.

ISSN:1784-3286    

DOI:10.1080/17843286.1988.11717945

出版商:Taylor&Francis    

年代:1988

数据来源: Taylor

摘要:

SummaryThis paper is a review (if the methods used in assessing the quality of medical care. In accordance with a previous classification scheme, five main groups of quality evaluation studies are examined, and current problems in evaluation are pointed out. The studies of the structure of care raise three problems: organizational features are possibly linked to mortality rates, cost-effective quality assurance settings remain to be selected, and the relationship between the physician performance and the quality of care is questionable. The studies of the process of care raise vexing issues of validity: auditing and peer review might lead to a deadly sameness, or might represent only attempts in containing utilization. There are stronger grounds for studying the outcomes of care. However, such studies are often limited to the medical aspects of outcomes. Gross measures of mortality are criticized: they are either valid, nor reliable measures of the quality of care. The studies combining process and outcome measures, e.g.«tracers», and the studies of strategies of care, e.g. decision-analysis-like audits, could provide strong foundations for quality assessment. There is a need for studying humanitarian aspects of care, that is, the art of care, and for developing patient-oriented measures of care, such as quality of life or satisfaction scales. The formulation of diseasespecific risks and prognoses could be a first step towards a common language between the physician and his patient.

ISSN:1784-3286    

DOI:10.1080/17843286.1988.11717946

出版商:Taylor&Francis    

年代:1988

数据来源: Taylor

摘要:

SummaryWe report the fortuitous discovery of a rigluatrial thrombus by two-dimensional echocardiography in a patient treated by repeated chemotherapy using a permanent intravenous catheter. Diagnosis, evolution and treatment of that right auricular thrombus arc briefly discussed. Performance of serial two-dimensional echocardiography in patients with permanent subcutaneously implanted catheters is suggested.»

ISSN:1784-3286    

DOI:10.1080/17843286.1988.11717947

出版商:Taylor&Francis    

年代:1988

数据来源: Taylor

摘要:

SummaryTwo eases of primary adenocarcinoma of the third part of the duodenum are reported. In the first patient, a possible association of the cancer with the sign of leser Trelat. was observed. In this patient, radiographical examination, perlormed two months prior to our investigation, was interpretated as normal. Only repeated Barium-studies. made because of persistant postprandial vomiting, provided definite diagnosis. In both cases.“curative”surgery consisted of segmental resection of a part of the duodenum. No recurrence is observed until now. twelve months and five years alter surgery.

ISSN:1784-3286    

DOI:10.1080/17843286.1988.11717948

出版商:Taylor&Francis    

年代:1988

数据来源: Taylor

ISSN:1784-3286    

DOI:10.1080/17843286.1988.11717949

出版商:Taylor&Francis    

年代:1988

数据来源: Taylor