摘要:

SummaryNormal subjects tolerate total obliteration of internal carotid artery, owing to three collateral channels : external carotid artery, Willis' polygone and peripheral arteries.A 50 % drop in systemic blood pressure makes the collateral system ineffective.All cerebral arteries, and particularly those constituting the collateral system, adapt their diameter to their blood flow. When the local blood flow decreases, as a result of atheromatous lesions located up-stream or of removal of an arterio-venous angioma situated downstream, the arterial diameter decreases and the vessel becomes less tortuous. These changes take place within about three weeks.When the cerebral blood flow decreases, the functional capacities of the cerebral cortex are altered. This state is reversible as long as the blood flow is maintained above a critical level.With arterial seriography, it is possible to measure the cerebral circulation time, which is found constant in the normal individual.In cerebral trauma, tumours and atheroma, blood can circulate at reduced flow in the whole brain or in some part of it. The circulatory defect parallels the evolution of coma, focal signs and electro-encephalographic abnormalities.Total obliteration of an artery by thrombosis is generally better tolerated than progressive stenosis by atheroma. In the latter case, the development of collateral channels is not as extensive.The syndromes of thrombosis and stenosis are differentiated.

ISSN:1784-3286    

DOI:10.1080/17843286.1962.11717701

出版商:Taylor&Francis    

年代:1962

数据来源: Taylor

摘要:

SummaryThe immediate course of acute cerebral ischaemia is not markedly influenced by anticoagulant therapy.Long term anticoagulant therapy seems to prevent recurrences of cerebral thrombo-embolic accidents.

ISSN:1784-3286    

DOI:10.1080/17843286.1962.11717702

出版商:Taylor&Francis    

年代:1962

数据来源: Taylor

摘要:

Summary1. The nutrition of the peripapillary region of the retina depends in part on the blood vessels of the optic nerve.2. There is an axial nutrition system in the optic nerve.3. The central retinal artery is not responsible for the nutrition of the optic nerve.4. The chiasma is irrigated by II arteries and by a network of anastomotic arterioles (prcchiasmatic, arteriolar arcade).5.The optical tract has a double vascularisation system (the anterior choroidal artery and the posterior communicating artery). This can explain the frequent absence of homonyme hemianopsia after ligation of the anterior choroidal artery.

ISSN:1784-3286    

DOI:10.1080/17843286.1962.11717703

出版商:Taylor&Francis    

年代:1962

数据来源: Taylor

摘要:

SummaryAn accurate diagnosis of disturbances in circulation can be made by ophtalmoscopy. The vascular phenomena observed in the eye fundus occur certainly also in other organs where a direct observation of the circulation is not possible.

ISSN:1784-3286    

DOI:10.1080/17843286.1962.11717704

出版商:Taylor&Francis    

年代:1962

数据来源: Taylor

摘要:

SummaryAuditory disturbances due to loss of sounds perception may be provoked by a decreased blood flow to the internal ear or to the higher nervous center. Permanent damage to these structures may result from the impairment of circulation. It is therefore important to detect these circulatory disturbances by laboratory and clinical investigations in order to institute as soon as possible an effective therapy.

ISSN:1784-3286    

DOI:10.1080/17843286.1962.11717705

出版商:Taylor&Francis    

年代:1962

数据来源: Taylor

摘要:

SummaryCyclophosphamide was injected weekly, intravenously, in 26 cases of solid tumors and in 15 cases of malignant lymphomas and leukemias. Six patients of the first group and 10 patients of the second group showed an objective remission. Objective remissions were observed in patients with lung cancer (4 cases), malignant melanoma and ano-rectal carcinoma (1 case of each), Hodgkin's disease (5 cases), chronic lymphatic leukemia (3 cases) and reticulum-cell sarcoma (2 cases).With the dosage regimen used in this series, leukopenia was frequent and thrombocytopenia was uncommon. Nausea and vomiting were the most frequent side-effects. Drug toxicity was suspected to be the cause of death in one case.Cyclophosphamide seems to have the same spectrum of activity as othei alkylating agents.Cases of malignant lymphoma resistant to other alkylating agents may be responsive to cyclophosphamide.

ISSN:1784-3286    

DOI:10.1080/17843286.1962.11717706

出版商:Taylor&Francis    

年代:1962

数据来源: Taylor