摘要:

SummarySome dynamic tests which may he used by clinicians are studied. Hypo-thalamo-pituitary-somatotrophic axis can be stimulated by insulin hypoglycemia, pyrogens,ß-methylcholine and total neurohypophyseal extracts; it is inhibited hy hyperglycemia.FSH blood level is reduced by oestrogen therapy while it is increased after the injection of neurohypophyseal extracts or synthetic oxytocin in young male. Testosterone is without effect on FSH in men while estrogens decreases FSH levels. The LH secretion is lowered alter oestrogen or testosterone injection and is increased, following injection of neurohypophyseal extracts in young male.

ISSN:1784-3286    

DOI:10.1080/17843286.1969.11716704

出版商:Taylor&Francis    

年代:1969

数据来源: Taylor

摘要:

SummaryThe effect of short-term treatment with chlorothiazide or chlothialidone on blood glucose and on glucose utilization has been studied in 21 healthy male, non obese patients. These drugs, given either orally or intravenously, have no«diabetogenic effect»under the conditions of this study.

ISSN:1784-3286    

DOI:10.1080/17843286.1969.11716705

出版商:Taylor&Francis    

年代:1969

数据来源: Taylor

摘要:

SummaryHypercorticism in obese patients, whether they are diabetic or not, is more apparent than actual for it is proportional to body surface. The behaviour of the adrenal cortex towards stimulation or inhibition is entirely normal in obesity.

ISSN:1784-3286    

DOI:10.1080/17843286.1969.11716706

出版商:Taylor&Francis    

年代:1969

数据来源: Taylor

摘要:

SummaryIllustrated by two personal cases, the authors discuss the interest of simultaneous determinations of blood glucose and plasma insulin for the diagnosis of pancreatic islet-cells tumors in several conditions : basal determinations, prolonged starvation and pharmacological tests using tolbutamide or glucagon. They report the interest of diazoxide in the management of these patients and present data indicating that this drug acts, at least in part, by a decrease in insulin secretion. In one case, they have studied the insulin content of the tumor and of the surrounding pancreas. They report the results of in vitro incubation of fragments of the tumor in the presence of glucose, at two different concentrations, and in the presence of glucose (too mg/ioo ml) plus tolbutamide (100 /µg/ml) or glucagon (5 /µg/ml).

ISSN:1784-3286    

DOI:10.1080/17843286.1969.11716707

出版商:Taylor&Francis    

年代:1969

数据来源: Taylor

摘要:

SummaryThe findings in two cases of islet tells pancreatic tumors have been presented. In one case, aortography led to accurate localisation of the tumor before operation. In the other case, biological tests are discussed on a physiopathologicai basis. It seems that insulin production by the tumor is usually not stimulated by glucose but well by leucine. This fact could explain the phenomenon of leucine induced hypoglycemia in insulin secreting adenomas. It is also suggested that the insulin secreting capacity of the remaining non tumoral pancreas is depressed during hyperglycemia and diminished tolerance to glucide could he explained by this mechanism.

ISSN:1784-3286    

DOI:10.1080/17843286.1969.11716708

出版商:Taylor&Francis    

年代:1969

数据来源: Taylor

ISSN:1784-3286    

DOI:10.1080/17843286.1969.11716709

出版商:Taylor&Francis    

年代:1969

数据来源: Taylor