ISSN:1784-3286    

DOI:10.1080/22953337.1982.11718854

出版商:Taylor&Francis    

年代:1982

数据来源: Taylor

摘要:

SummaryContinuous subcutaneous insulin infusion (CSII) was performed in 3 totally insulin dependent diabetic patients (postprandial C peptide: 0.03±0.01 pmol/l) for periods lasting up to 9 months. During this period, each patient measured his capillary blood glucose 2 to 5 times per day with the Dextrosix(R)/Dextrometer(R)method. A good glycemic control was achieved at home, as assessed by a mean plasma glucose level of±140 mg/dl and a M value ranging from 9 to 24. The mean total glycosylated hemoglobin levels in the 3 patients were 9.3, 9.2 and 11.9% respectively. Hypoglycemic episodes were rarely observed; CSII did not affect the usual way of life of the patients. We did not observe any improvement of the conduction velocy of sciatic nerves, as assessed by electro-myography after a few months of CSII.We conclude that a good glycemic profile can be obtained at home in totally insulin dependent patients with CSII.

ISSN:1784-3286    

DOI:10.1080/22953337.1982.11718855

出版商:Taylor&Francis    

年代:1982

数据来源: Taylor

摘要:

SummaryTwo cases of Acanthosis Nigricans are presented. The first one is associated with a breast cancer. The rarety of this association is outlined. The paraneoplastic nature of the malignant form is admitted but the mechanisms of its apparition remain unknown. The second case illustrates the benign form associated with an endocrinopathy and chiefly with a very important obesity.

ISSN:1784-3286    

DOI:10.1080/22953337.1982.11718856

出版商:Taylor&Francis    

年代:1982

数据来源: Taylor

摘要:

SummaryThe in vitro activity of dibekacin, a new aminoglycoside, has been compared to that of tobramycin and other antibiotics, against over 500 clinical isolates ofEnterobacteriaceae, Pseudomonasand staphylococci. The activity of dibekacin was similar to that of tobramycin. About 40 % of the gentamicinresistantEnterobacteriaceaeremained susceptible to dibekacin.A pharmacokinetic cross-over study of dibekacin and tobramycin was conducted in 6 healthy volunteers. After IV bolus injection and IM administration of single doses of 75 mg the pharmacokinetic parameters of both aminoglycosides appeared to be very similar: half-life times between 1.9 and 2.0 h, mean peak serum levels of 2.5 and 2.3 ug/ml after IM administration with a bio-availability of 100%, and a mean urinary recovery in 24 h between 72 % and 84 % of the dose.

ISSN:1784-3286    

DOI:10.1080/22953337.1982.11718857

出版商:Taylor&Francis    

年代:1982

数据来源: Taylor

摘要:

SummaryA patient with endocarditis caused byCardiobacterium hominisis described. During the course of the illness, this patient developed a generalised bullous eruption, which appeared before he received any drug therapy. Skin biopsy showed evidence of vasculitis. To our knowledge a similar clinical appearance ofC. hominisendocarditis has not yet been described.

ISSN:1784-3286    

DOI:10.1080/22953337.1982.11718858

出版商:Taylor&Francis    

年代:1982

数据来源: Taylor

摘要:

SummaryWe report a case of group JK Diphteroids and Candida albicans sepsis in a leukaemic patient under chemotherapy.This case stresses the interest of identification of Diphteroids isolated repeatedly from blood cultures.

ISSN:1784-3286    

DOI:10.1080/22953337.1982.11718859

出版商:Taylor&Francis    

年代:1982

数据来源: Taylor

摘要:

SummaryAngiotensin-I-converting enzyme is responsible for the conversion of angiotensin I to the potent vasopressor angiotensin II and for degrading the vasodepressor bradykinin. Several converting-enzyme inhibitors have been synthesized of which captopril has been most widely used in human hypertension. This review deals with its pharmacology, haemodynamic effects, mechanisms of action, clinical usefulness and side-effects. It is concluded that converting-enzyme inhibitors are a new and interesting group of antihypertensive agents. However, the toxicity of the first molecule, captopril, remains a serious problem: prescription of this drug should be limited to specific forms of hypertension.

ISSN:1784-3286    

DOI:10.1080/22953337.1982.11718860

出版商:Taylor&Francis    

年代:1982

数据来源: Taylor

ISSN:1784-3286    

DOI:10.1080/22953337.1982.11718861

出版商:Taylor&Francis    

年代:1982

数据来源: Taylor

ISSN:1784-3286    

DOI:10.1080/22953337.1982.11718862

出版商:Taylor&Francis    

年代:1982

数据来源: Taylor

ISSN:1784-3286    

DOI:10.1080/22953337.1982.11718863

出版商:Taylor&Francis    

年代:1982

数据来源: Taylor