摘要:

SummaryThe therapeutic use of fructose can be justified in two acute conditions : serious liver failure and diabetic coma.Other clinical applications will certainly be found but are not yet fully demonstrated.Fructose should be administered intravenously for it is converted to glucose in the intestinal wall after its ingestion. Even if its therapeutic usefulness is limited for the present time, the biochemical and physiologic observations it has yielded so far, are of great value.

ISSN:1784-3286    

DOI:10.1080/17843286.1958.11717514

出版商:Taylor&Francis    

年代:1958

数据来源: Taylor

摘要:

SummaryArterial and venous ammonia were studied in different diseases by a modified Conway method.In cirrhosis, the correlation between mental state and arterial ammonia was good; with venous blood, the relationship was poor. In comæof other origin (uremia, cerebral thrombosis, etc.), blood ammonia remained quite normal. After abdominal paracentesis, blood ammonia did not rise. Ammonia concentration in ascitis was different from arterial or peripherical venous blood ammonia.The authors could confirm the existence of an important ammoniacal arterio-venous difference in impending hepatic coma and in hepatic coma. This difference did not completely disappear after warming of the leg. The significance of that arterio-venous difference, the physiopathology of hepatic coma, and the concomitant disturbances of the intermediary metabolism are discussed.The auhors stress the importance of arterial ammonia determination for the adjustment of protein intake to the individual tolerance of each cirrhotic patient.The cases studied here show that protein restriction is not only useful in the treatment of impending hepatic coma; it also improves the more chronic mental troubles which occur in some cases of severe cirrhosis.Nevertheless, food adjustment and antibiotherapy do not prevent the usual complications of cirrhosis, especially upper gastro-intestinal bleedings.

ISSN:1784-3286    

DOI:10.1080/17843286.1958.11717515

出版商:Taylor&Francis    

年代:1958

数据来源: Taylor

摘要:

SummaryThe analysis of 200 radioiodine diagnostic tests shows that the iodine collection curve gives results far more valuable than a single 24th hour determination that can ignore an early maximum of collection.The curves showing an early maximum and a significant fall at the 24th hour seem characteristic of hyperthyroidism, even if the values reached at the second and sixth hour are not up to 40 % of the ingested dose.The bell-shaped curves reaching a maximum of uptake superior to 40 % at the 24th hour are less characteristic. Beside cases of hyperthyroidism, the same type of curve can be obtained in euthyroid patients with familial goiters, in certain puberty and juvenile goiters and sometimes after antithy oid drugs.The same shape of curve is found in subjects submitted to a relative lack of iodine due to consumption of water from local sources or wells, what is not exceptional in rural areas.The complementary triiodothyronine test permits to depart the numerous cases where the collection test has given doubtfull results. In hyperthyroid patients, triiodothyronine is usually unable to reduce the high iodine uptake. In euthyroid subjects with goiter, on the contrary, the collection level falls at least of 30 % after 10 days.It is exceptional that this test is not able to provide a valuable answer. Some rare diffuse or nodular goiters in euthyroid patients may notwithstanding keep a high collection level inspite of the administration of triiodothyronine during 10 and even 20 days.

ISSN:1784-3286    

DOI:10.1080/17843286.1958.11717516

出版商:Taylor&Francis    

年代:1958

数据来源: Taylor

摘要:

SummaryHorton’s disease (also called temporal, cranial or giant cell arteritis) is a diffuse disease of the vessels, of unknown origin (bacterial allergy ?), affecting old people.It begins with non-specific symptoms (malaise, loss of weight, anorexia, fever) followed by severe head aches accompanied by inflammation of one or more of the temporal arteries.It is often complicated by severe ocular symptoms (amblyopia, amaurosis) and by other less frequent localizations (brain, myocardium, mesenterium, etc.).It is characterized by successive phases of progress and remission lasting, on the average, from 2 to 6 months.Prognosis quoad vitam is relatively good.Pathology evidences lesions of periarteritis with giant cells involving mainly the cranial arteries.Blood sedimentation rate is always much increased. Protidemia is perturbed with increase of theα2and theγglobulins and decrease of the albumins.Results of therapy associating antibiotics with ACTH or the corticosteroids appear to be most encouraging.

ISSN:1784-3286    

DOI:10.1080/17843286.1958.11717517

出版商:Taylor&Francis    

年代:1958

数据来源: Taylor

ISSN:1784-3286    

DOI:10.1080/17843286.1958.11717520

出版商:Taylor&Francis    

年代:1958

数据来源: Taylor