ISSN:1784-3286    

DOI:10.1080/17843286.1992.11718224

出版商:Taylor&Francis    

年代:1992

数据来源: Taylor

摘要:

SummaryIn this study, the immediate and short-term outcome of 9 consecutive patients aged 80 years or older undergoing percutaneous transluminal coronary angioplasty (PTCA) are reported. Of these 9 patients, 8, despite optimal medical therapy, had unstable Class IV anginal symptoms and 6 had multivessel coronary artery disease. Primary success at PTCA (successful dilation of all attempted lesions without any complications) was achieved in 8 of the 9 (89%) patients. The one patient with unsuccessful PTCA had subsequent successful elective coronary bypass graft surgery. The 8 patients with primary success at PTCA have been followed up for a mean of 27±15(range: 6 to 45) months. During follow-up, no patient died, required a further revascularization procedure or had a myocardial infarction. Indeed, 7 of these 8 patients have, following PTCA, remained entirely asymptomatic with no decrease in their activity level. Angina has recurred in 1 patient but it is mild and does not restrict his activities. Based on our encouraging experience we suggest that PTCA should be considered favourably in the treatment of selected octogenarian patients with severe angina poorly controlled by medical therapy.

ISSN:1784-3286    

DOI:10.1080/17843286.1992.11718225

出版商:Taylor&Francis    

年代:1992

数据来源: Taylor

摘要:

SummaryThe«largc cell anaplastic lymphoma, Ki–1 posili ve»is a recently described lymphoma subtype (about 1–8% of all NHL).Distinction from Hodgkin’s disease and true histiocytic lymphoma/malignant histiocytosis is not always possible, even by experienced pathologists. It was recently incorporated in the updated Kiel Classification of lymphomas. Classical histologic appearance is a sinusoidal growth pattern in lymph nodes and presence of large bizarre anaplastic cells. Use of cellmarkers LCA, EM A and Ki-1 or Ber-H2 is essential for diagnosis.The mean age of patients is 50 years. Approximately 50% of patients have an advanced stage (III-IV). Prognosis depends on age and tumor localisations. Cutaneous involvement only is usually associated with a good prognosis. Median survival for patients with extra-cutaneous disease is 13 months. Treatment with intensive chemotherapy is usually needed. Long term remissions are more frequently seen in children and adolescents.

ISSN:1784-3286    

DOI:10.1080/17843286.1992.11718227

出版商:Taylor&Francis    

年代:1992

数据来源: Taylor

摘要:

SummaryIt is well established that Tamoxifen is an excellent adjuvant therapy in cases of breast cancer, with very few side effects. After menopause this drug can act as a weak estrogen at the level of the genital tract and cases of endometrial hyperplasia and adenocarcinomas have been reported. During premenopausal years its action depends on the mode of administra-tionxontinue or cyclical, during proliferative or luteal phase. The occurrence of ovarian cysts seems more frequent than in a control group. It should thus be advised to consider Tamoxifen as a good antioestrogen at the level of the breast but as an active hormonal substance at the gynaecological level, and to offer the patient the adequate follow-up which seems necessary.

ISSN:1784-3286    

DOI:10.1080/17843286.1992.11718228

出版商:Taylor&Francis    

年代:1992

数据来源: Taylor

摘要:

SummaryExtracorporeal shock wave lithotripsy of gallstones is a safe and well-tolerated procedure. Patients are now treated without general anesthesia and, increasingly, on an outpatient basis. Skin petechiae and transient hematuria are the most common side effects. Episodes of biliary colic are common in the follow-up period, but more serious adverse side effets such as cholecystitis and pancreatitis are distinctly uncommon. It is estimated that only 15 % to 20 % of all patients with symptomatic cholelithiasis are suitable lithotripsy candidates. As our knowledge of the procedure grows, it seems clear that the best results arc obtained in patients with solitary radiolucent stones<20 mm, with stone-free rates at 12 months above 80 %, for this selected group of patients. Adjuvant oral bile-acid dissolution therapy should be used in conjunction with gallstone lithotripsy. Gallstone recurrence remains to be established by clinical studies.Therapy forgallstones in 1991 has to be reevaluated by an interdisciplinary approach, taking into account not only open cholecystectomy, but also other modalities such as medical dissolution, laparoscopic surgery, percutaneous cholecystolithotomy and extracorporeal shock wave lithotripsy. The appeal of the laparoscopic approach will substantially reduce the pool of patients for lithotripsy. Nevertheless, lithotripsy will continue to be a viable treatment option for patients with a single radiolucent stone. It is an outpatient procedure and doesn’t require any incision or general anesthesia.

ISSN:1784-3286    

DOI:10.1080/17843286.1992.11718229

出版商:Taylor&Francis    

年代:1992

数据来源: Taylor

摘要:

SummaryThe hepatotoxicity of tetracyclines is well known. If microvesicular steatosis due to a high dose of tetracycline has virtually disappeared, it can also be observed with otherdrugs belonging to the tetracycline family. To our knowledge, hepatotoxicity induced by doxycycline has never been reported.In our patient, the abrupt onset of hepatic failure, five days after the start of doxycycline and the rapid normalization after the drug was stopped, leads to suspect acausal relationship between doxycycline and liver insufficiency. We must however be careful before concludi ng, because our patient received also acety Isalicylic acid and paracetamol, two other potential hepatotoxic drugs.Acta Clin Belg 47, 3 205–8

ISSN:1784-3286    

DOI:10.1080/17843286.1992.11718230

出版商:Taylor&Francis    

年代:1992

数据来源: Taylor

摘要:

SummaryA case of chronic biliary fasciolasis is reported, which was confirmed by endoscopic retrograde cholangiography. After unsuccessful attempts of treatment with classic antiparasitic drugs, cure was obtained with triclabendazole the absorption of which was studied.

ISSN:1784-3286    

DOI:10.1080/17843286.1992.11718231

出版商:Taylor&Francis    

年代:1992

数据来源: Taylor

ISSN:1784-3286    

DOI:10.1080/17843286.1992.11718232

出版商:Taylor&Francis    

年代:1992

数据来源: Taylor

ISSN:1784-3286    

DOI:10.1080/17843286.1992.11718233

出版商:Taylor&Francis    

年代:1992

数据来源: Taylor

ISSN:1784-3286    

DOI:10.1080/17843286.1992.11718234

出版商:Taylor&Francis    

年代:1992

数据来源: Taylor