摘要:

Summary1. In six cases of myeloma, the blood proteins have been studied by the method of fractioned precipitation with potassium phosphat.According to Florkin and Duchâteau, this method reveals in the normal blood serum 5 protein fractions, of which I, II and III approximately correspond to the globulins.2. The abnormalities observed in the composition of the serum were as follows :—Fraction I was 10 to 12 times higher than normal in two cases; consequently, the total proteinemia was definitely increased (96 and 117 gr. of proteins per liter). In the four other cases, fraction I was much reduced, sometimes completely absent ; the total proteinemia was normal or lowered (80 and 46 gr. of proteins per liter).—Fraction II was obviously increased in two cases (2 to 3 times the normal value).—Fraction V was decreased in three cases and reduced to 1/2, 1/3 and 1/5 of the normal value.—The other fractions showed no significant changes.3. Four of the six studied patients showed Bence-Jones proteinuria. The solubility of the urinary proteins when increasing concentration of potassium phosphate were added has been established in three of them. In one case, the urinary protein was found to be homogenous and to behave as a globulin of low solubility. In the second case, two proteins were found in the urine : one albumin and one globulin of low solubility. In the third case, three proteins were demonstrated : one albumin and two globulins rather soluble.4. There is, in this group of six cases, a correlation between the abnormalities of fraction I of serum proteins and Bence-Jones proteinuria. In the 4 cases where this proteinuria was noticed, fraction I was much lowered or absent. In the two cases where no proteinuria was found, fraction I was much increased.The significance of this correlation is discussed.

ISSN:1784-3286    

DOI:10.1080/17843286.1949.11716516

出版商:Taylor&Francis    

年代:1949

数据来源: Taylor

摘要:

SummaryThe author emphasizes that a thrill in diffuse goitre always means toxicity when the goitre is not too large.However, in rare cases of larger goitres a thrill may be observed without toxicity.

ISSN:1784-3286    

DOI:10.1080/17843286.1949.11716517

出版商:Taylor&Francis    

年代:1949

数据来源: Taylor

摘要:

SummaryMuch work has been done about the function of the spleen, and hitherto our really positive knowledge has remained still incomplete. The different functions so far known are discussed.Detailed study of the influence of regular bloodtapping and of continued hæmolysis on the spleen. After a certain time of bloodtapping the spleen becomes smaller and becomes finally so small that the weight is reduced to less than 50 mgr. These spleens are so atrophic that it can scarcely be imagined that the normal hæmolysis of blood can be located in this atrophic organ. The various depotfunctions of the spleen have become superfluous. Of the other functions described are two dealing with bloodformation. The first is that the spleen should exercise a stimulating influence on the bloodformation in the bone marrow. A second conception presumes that the spleen should exercise a checking influence on the outgoings of the erythrocytes from their places of formation in the restituting blood. The spleen would prevent the bone marrow from functioning too actively. The first conception is hard to bring into accord with the almost entire disappearance of the spleen. For it is the very bone marrow which must be whipped up to maximal activity, and consequently an extra function of the spleen might be expected, On the other hand it is logical that with top-anemia the checking function will fall out. Here all bloodcells made, must be brought as quickly as possible in the blood channel.In a second group of experiments was shown that in anemic rabbits injection of splenic tissue recovering from the existing anemia is slower than normal.At the same time We see a reticulocytosis not as a temporary phenomenon, but persists in proportion to the existing anemia.Finally a new untill now unknown function of the spleen is discussed. In the bone marrow we can find anticomplementary factors which are regulated by the spleen.

ISSN:1784-3286    

DOI:10.1080/17843286.1949.11716518

出版商:Taylor&Francis    

年代:1949

数据来源: Taylor

摘要:

SummaryThe author has studied a patient with Fallot’s disease. Catheterism of the right cavities, Bing’s test, oxygen saturation test of arterial blood, metabolism suggested that the blood flow through the lungs was only moderately reduced. For this reason surgery did not seem indicated.The author emphasizes the necessity of such studies in order to avoid useless operations.

ISSN:1784-3286    

DOI:10.1080/17843286.1949.11716519

出版商:Taylor&Francis    

年代:1949

数据来源: Taylor

摘要:

SummaryAuthors report on a case of achrestic anemia with symptoms of intravascular hemolysis.The patient was a 49 years old man. He died when operated for intestinal obstruction.Post mortem examination showed on the distal part of the small bowel two sheathes of non inflammatory tissue resulting in thickening of the walls and narrowing of the bowel lumen.Authors discuss the possible relation between the anemia and the intestinal lesions. They suggest that the last are secondary to the anemia and, on the basis of microscopic observations, that they recognize an allergic origin.

ISSN:1784-3286    

DOI:10.1080/17843286.1949.11716520

出版商:Taylor&Francis    

年代:1949

数据来源: Taylor

摘要:

SummaryA case of Besnier-Boeck’s sarcoïdosis of lungs and lymph nodes is reported. The interest of this case was that bronchoscopy permitted biopsy of sarcoïdosic nodes. Under the microscope were observed intracellular hyaline inclusions of various forms.Streptomycin was tried, but without success. Recent data on sarcoïdosis are reviewed in this article.

ISSN:1784-3286    

DOI:10.1080/17843286.1949.11716521

出版商:Taylor&Francis    

年代:1949

数据来源: Taylor

摘要:

SummaryReport of a case of hysterical dyspnea in a female of 21 years, with moderate tachypnea and pseudo-spasm of the larynx. The patient was cured by isolation.Clinical and physiological analysis of the case prove the occurence of moderate overventilation of strictly limited sectors of the lungs (apex). Light and chronic acapnia and alcalosis result therefrom.To account for absence of cyanosis and true dyspnea, redistribution of the blood’s circulation within the lungs has been postulated

ISSN:1784-3286    

DOI:10.1080/17843286.1949.11716522

出版商:Taylor&Francis    

年代:1949

数据来源: Taylor

摘要:

SummaryThe author reviews experimental work on which existence of a collateral respiration is based. This has been observed only between pulmonary«segments»but not between pulmonary lobes where the lobes are well separated by the scissures.The author emphasizes the importance of the collateral respiration especially in the pathogeny of atelectasis following surgery or bronchitis localised to the median right lobe.

ISSN:1784-3286    

DOI:10.1080/17843286.1949.11716523

出版商:Taylor&Francis    

年代:1949

数据来源: Taylor

ISSN:1784-3286    

DOI:10.1080/17843286.1949.11716524

出版商:Taylor&Francis    

年代:1949

数据来源: Taylor