摘要:

SummaryEach hypertensive patient should have a thorough kidney investigation. A possible stenosis of the renal artery has to be considered, where the renal tissue seems normal.The purpose of this paper was to review the several methods of investigation, each with their utility : the suggestive signs of Poutasse, the total kidney functions, the TEAC test, the isotopic nephrogram, the comparison of the renal function and finally the aortorenography.The contraindications of these investigations are summarized. A few typical personal observations of renovascular pathology are described. In their conclusion, the authors suggest to reserve an aortorenography only for these cases, where the other screening tests indicate the probability of an arterial lesion.

ISSN:1784-3286    

DOI:10.1080/17843286.1962.11717714

出版商:Taylor&Francis    

年代:1962

数据来源: Taylor

摘要:

SummaryThe therapeutic action of 16-formylgitoxine has been evaluated in 33 patients. Four of these patients suffered from paroxystic tachycardia; all others were in congestive heart failure with sinusal rhythm in 17, atrial fibrillation in 10 and permanent flutter in 2.Conclusions drawn from the present studies are as follows:1. 16-formylgitoxine is a highly potent cardiotonic drug. The amount required for full digitalization per os averaged 2 to 3 mg given over a period of 3 to 4 days. The maintenance dosage ranged from 0.1 to 0.4 mg daily per os, which is slightly more than when digitoxin is used, but less than in case of use of digoxin or lanatoside C.2. Conversion of a permanent flutter into atrial fibrillation was achieved with 4 to IO mg 16-formylgitoxine given over 7 to 10 days.3. One mg 16-formylgitoxine injected intravenously exerts a near maximal effect in less than 40 minutes, which makes it comparable to digoxine or lanatoside C. The latter two drugs may thus be replaced by 16-formylgitoxine for emergency treatment of cardiac failure associated with tachyarrhythmia or of paroxystic tachycardias (auricular fibrillation, flutter, supraventricular tachycardia). In such cases, 1 mg should be given intravenously, and again one hour later if need be.4. The amount of drug required for full digitalization is 1.0 to 2 mg administered intravenously.5. Only 3 patients, out of 33, complained of gastric intolerance; this side effect is thus less frequently encountered than when digitoxine is prescribed.6. 16-formylgitoxine has a marked diuretic action, to be ascribed to hemodynamic changes rather than to a direct renal influence of the glycoside, since the drug failed to induce a diuresis in a case of constrictive pericarditis.

ISSN:1784-3286    

DOI:10.1080/17843286.1962.11717715

出版商:Taylor&Francis    

年代:1962

数据来源: Taylor

摘要:

SummaryAfter having reviewed the various biological tests utilized for the diagnosis of myocardial infarction and concluded to their lack of specificity, we report our experience with the determination in blood of phospho-creatin-kinase (P.C.K.) which is a specific muscular and myocardial enzymeWe have found an elevation of the blood level of P.C.K. only in diseases causing a necrosis of skeletal or heart muscles.By contrast, we have found a normal level of P.C.K. in a whole series of pathological conditions, including coronary sclerosis. The rise of the serum level of P.C.K. appears on the first day, as for SGOT, but does not persist more than 48 to 72 hours after myocardial infarction.Therefore we conclude that the determination of the serum level of P.C.K., in view of the specificity of P.C.K. for muscular tissue has a practical interest in the precocious detection of myocardial infarction. Nevertheless the determination of the sedimentation rate and the C.R.P. remains useful to follow the evolution of myocardial infarct.

ISSN:1784-3286    

DOI:10.1080/17843286.1962.11717716

出版商:Taylor&Francis    

年代:1962

数据来源: Taylor

摘要:

SummaryA case of hypercalcemic syndrome is reported in a patient with ovarian carcinoma without evidence of bone metastases. After surgical removal of the tumor, Ca and P metabolism returned to normal.Tubular reabsorption of phosphorus was studied before and after the intervention. The action of the ovarian tumor appears to be comparable to that of the parathyroid glands.

ISSN:1784-3286    

DOI:10.1080/17843286.1962.11717717

出版商:Taylor&Francis    

年代:1962

数据来源: Taylor

摘要:

SummaryDifferent types of congenital haemolytic anaemia are reviewed, with special reference to deficiency of glucose-6-phosphate dehydrogenase. Aetiolo-gical, hereditary and clinical aspects are briefly presented. After a short review of the structure and metabolism of the erythrocyte, the pathogenesis of haemolysis is dealt with in some detail : in the presence of certain definite compounds, G-6-PD deficiency leads to a fall in TPNH and reduced glutathion levels. The various theories put forward to explain the mechanisms of haemolysis and the origin of methaemoglobin and Heinz bodies, are discussed.Certain biochemical abnormalities observed in other congenital haemolytic syndromes are also presented.

ISSN:1784-3286    

DOI:10.1080/17843286.1962.11717718

出版商:Taylor&Francis    

年代:1962

数据来源: Taylor