摘要:

SummaryAfter an analysis of the consequences of hypercorticism, the three causes of Cushing syndrome ate considered : adrenal tumour, paramoplasic syndrome and Cushing disease (hypereorticism of central origin).The Characteristics of hypereorticism in Cushing disease are described, as well as the changes in ACTH secretion, the anomalies of the feed-back ACTH-Cortisol system, the frequency, type and initial symptomatology of pituitary tumours. A physiopathologic concept is proposed : Cushing disease could be due to hypothalamic disturbance and primary central hypertonia of undetermined origin, responsible of pituitary stimulation, leading to adrenal hyperplasia.The created pituitary disturbance could be the site of single overactivity of micro-adenomas or of a single tumour which could make its appearance after adrenalectomy; the adrenals would show single diffuse or micro-adenomatous hyperplasia. The different histologic pictures of the pituitary or of the adrenals would constitute successive steps of a similar pathologic process.

ISSN:1784-3286    

DOI:10.1080/17843286.1969.11716710

出版商:Taylor&Francis    

年代:1969

数据来源: Taylor

摘要:

SummaryThe authors report two hundred cases of poisoning by narcotics or anti-depressive drugs. They review the major complications encountered in these patients : respiratory failure (of central origin or through airway obstruction) is one of the most frequent sign found in severe poisoning. Shock or cardiac arrhythmias are sometimes observed, mainly in the patients poisoned by imino-dibenzyl derivatives.After a short review of the first measures of resuscitation, the authors insist on the importance of intensive care in the treatment of poisoning. Respiratory assistance is primordial : 59 patients had to be artificially ventilated after endotracheal intubation. Massive infusions (of alkaline solution in barbiturate poisoning) enhance the urinary excretion of the poison and contribute in maintaining good circulatory conditions.Among these 200 patients, 198 recovered completely. Two died : they had been admitted to hospital in a decerebrated status or in irreversible coma.Patients suffering from acute poisoning should be rapidly transferred to an intensive care unit where adequate therapy will be applied until the patient awakes.

ISSN:1784-3286    

DOI:10.1080/17843286.1969.11716711

出版商:Taylor&Francis    

年代:1969

数据来源: Taylor

摘要:

SummaryKolar and Hots's technique has been applied by the authors to the cytology of cerebrospinal fluid in order 10 obtain a spontaneous sedimentation of the cells.The results show that this method brings a progress compared to previous procedures.The authors are conviced of the utility of this technique to demonstrate leukemic infiltration of the nevraxis.

ISSN:1784-3286    

DOI:10.1080/17843286.1969.11716712

出版商:Taylor&Francis    

年代:1969

数据来源: Taylor

摘要:

SummaryThe authors describe two cases of infectious mononucleosis with important thrombocytopenia, They comment the pathogenesis and the treatment of this rare complication.

ISSN:1784-3286    

DOI:10.1080/17843286.1969.11716713

出版商:Taylor&Francis    

年代:1969

数据来源: Taylor

摘要:

SummaryThe analysis of the ocular manifestations encountered in some inherited disorders of metabolism demonstrated their frequency and diagnostic values in this type of diseases. The inborn errors of metabolism analyzed are : cystinosis. Wilson, Hurler and Fabry diseases, galactosemia, haemocystnuria. alcaptonuria, albinism, familial amaurotic idiocy, Niemann-Pick disease, metachromatic leuco-dystrophy and Farber disease.

ISSN:1784-3286    

DOI:10.1080/17843286.1969.11735729

出版商:Taylor&Francis    

年代:1969

数据来源: Taylor

ISSN:1784-3286    

DOI:10.1080/17843286.1969.11716715

出版商:Taylor&Francis    

年代:1969

数据来源: Taylor